The CD19-CD21 signal transduction complex of B lymphocytes regulates the balance between health and autoimmune disease: systemic sclerosis as a model system.
about
CD19 chimeric antigen receptor (CD19 CAR)-redirected adoptive T-cell immunotherapy for the treatment of relapsed or refractory B-cell Non-Hodgkin's LymphomasImmune-mediated animal models of Tourette syndrome.Inhibitory role of CD19 in the progression of experimental autoimmune encephalomyelitis by regulating cytokine responseB-lymphocyte depletion reduces skin fibrosis and autoimmunity in the tight-skin mouse model for systemic sclerosisCD19 expression in B cells is important for suppression of contact hypersensitivity.Polymorphism of immunoglobulin enhancer element HS1,2A: allele *2 associates with systemic sclerosis. Comparison with HLA-DR and DQ allele frequencyReference-free deconvolution of DNA methylation data and mediation by cell composition effects.A CD21 low phenotype, with no evidence of autoantibodies to complement proteins, is consistent with a poor prognosis in CLLCD19 regulates skin and lung fibrosis via Toll-like receptor signaling in a model of bleomycin-induced scleroderma.Development of an isoform-specific gene suppression system: the study of the human Pax-5B transcriptional element.B Cell in Autoimmune Diseases.The development and function of regulatory B cells expressing IL-10 (B10 cells) requires antigen receptor diversity and TLR signals.Regulatory B cells (B10 cells) have a suppressive role in murine lupus: CD19 and B10 cell deficiency exacerbates systemic autoimmunity.Basal B cell receptor-directed phosphatidylinositol 3-kinase signaling turns off RAGs and promotes B cell-positive selection.Analysis of complement biomarkers in systemic sclerosis indicates a distinct pattern in scleroderma renal crisis.Abnormal B lymphocyte activation and function in systemic sclerosis.Differential phosphorylation of functional tyrosines in CD19 modulates B-lymphocyte activation.Peripheral CD19hi B cells exhibit activated phenotype and functionality in promoting IgG and IgM production in human autoimmune diseasesAnalyses of 123 Peripheral Human Immune Cell Subsets: Defining Differences with Age and between Healthy Donors and Cancer Patients Not Detected in Analysis of Standard Immune Cell Types.
P2860
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P2860
The CD19-CD21 signal transduction complex of B lymphocytes regulates the balance between health and autoimmune disease: systemic sclerosis as a model system.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
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name
The CD19-CD21 signal transduct ...... c sclerosis as a model system.
@ast
The CD19-CD21 signal transduct ...... c sclerosis as a model system.
@en
type
label
The CD19-CD21 signal transduct ...... c sclerosis as a model system.
@ast
The CD19-CD21 signal transduct ...... c sclerosis as a model system.
@en
prefLabel
The CD19-CD21 signal transduct ...... c sclerosis as a model system.
@ast
The CD19-CD21 signal transduct ...... c sclerosis as a model system.
@en
P2093
P356
P1476
The CD19-CD21 signal transduct ...... c sclerosis as a model system.
@en
P2093
Jonathan C Poe
Karen M Haas
Manabu Fujimoto
Shinichi Sato
Thomas F Tedder
P356
10.1159/000082087
P577
2005-01-01T00:00:00Z