Sonic hedgehog-dependent activation of Gli2 is essential for embryonic hair follicle development. - Wikidata - wikimedia - TriplyDB

Sonic hedgehog-dependent activation of Gli2 is essential for embryonic hair follicle development.

Sonic hedgehog-dependent activation of Gli2 is essential for embryonic hair follicle development.

http://www.wikidata.org/entity/Q35963725

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Regulatory role for Krüppel-like zinc-finger protein Gli-similar 1 (Glis1) in PMA-treated and psoriatic epidermis.MIM/BEG4, a Sonic hedgehog-responsive gene that potentiates Gli-dependent transcription Indian hedgehog and beta-catenin signaling: role in the sebaceous lineage of normal and neoplastic mammalian epidermis EDA signaling and skin appendage development GLI2-specific transcriptional activation of the bone morphogenetic protein/activin antagonist follistatin in human epidermal cells Signalling in the epidermis: the E2F cell cycle regulatory pathway in epidermal morphogenesis, regeneration and transformation Wnt signaling induces epithelial differentiation during cutaneous wound healing Gorab Is Required for Dermal Condensate Cells to Respond to Hedgehog Signals during Hair Follicle Morphogenesis Gene Expression and Proteome Analysis as Sources of Biomarkers in Basal Cell Carcinoma Trps1 and its target gene Sox9 regulate epithelial proliferation in the developing hair follicle and are associated with hypertrichosis Role of epidermal primary cilia in the homeostasis of skin and hair follicles Planar cell polarity effector gene Intu regulates cell fate-specific differentiation of keratinocytes through the primary cilia Fibroblast growth factor signals regulate a wave of Hedgehog activation that is essential for coronary vascular development GATA-3: an unexpected regulator of cell lineage determination in skin Transcriptome analysis of tetraploid cells identifies cyclin D2 as a facilitator of adaptation to genome doubling in the presence of p53 Mice with a targeted mutation of patched2 are viable but develop alopecia and epidermal hyperplasia Abnormal hair development and apparent follicular transformation to mammary gland in the absence of hedgehog signaling Dual role of COUP-TF-interacting protein 2 in epidermal homeostasis and permeability barrier formation Network modeling of TGFβ signaling in hepatocellular carcinoma epithelial-to-mesenchymal transition reveals joint sonic hedgehog and Wnt pathway activation An essential role for dermal primary cilia in hair follicle morphogenesis.Hedgehog-dependent proliferation drives modular growth during morphogenesis of a dermal bone Cancer susceptibility and embryonic lethality in Mob1a/1b double-mutant mice.Early epithelial signaling center governs tooth budding morphogenesis Matrix rigidity induces osteolytic gene expression of metastatic breast cancer cells.Sustained Hedgehog signaling is required for basal cell carcinoma proliferation and survival: conditional skin tumorigenesis recapitulates the hair growth cycle Inhibition of hedgehog signaling decreases proliferation and clonogenicity of human mesenchymal stem cells.Exploiting the keratin 17 gene promoter to visualize live cells in epithelial appendages of mice.Transcriptional control of epidermal specification and differentiation.Primary cilia can both mediate and suppress Hedgehog pathway-dependent tumorigenesis.Key tumor suppressor genes inactivated by "greater promoter" methylation and somatic mutations in head and neck cancer.Small-molecule modulators of the Sonic Hedgehog signaling pathway.MicroRNA-214 controls skin and hair follicle development by modulating the activity of the Wnt pathway.The effects of Hedgehog on the RNA-binding protein Msi1 in the proliferation and apoptosis of mesenchymal stem cells.Sonic hedgehog-induced type 3 deiodinase blocks thyroid hormone action enhancing proliferation of normal and malignant keratinocytes.Highly upregulated Lhx2 in the Foxn1-/- nude mouse phenotype reflects a dysregulated and expanded epidermal stem cell niche.TGF-beta promotion of Gli2-induced expression of parathyroid hormone-related protein, an important osteolytic factor in bone metastasis, is independent of canonical Hedgehog signaling Hedgehog signaling regulates telomerase reverse transcriptase in human cancer cells Gli activity is critical at multiple stages of embryonic mammary and nipple development.GLI2 transcription factor mediates cytokine cross-talk in the tumor microenvironment.The critical roles of serum/glucocorticoid-regulated kinase 3 (SGK3) in the hair follicle morphogenesis and homeostasis: the allelic difference provides novel insights into hair follicle biology.

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P2860

Sonic hedgehog-dependent activation of Gli2 is essential for embryonic hair follicle development.

http://www.wikidata.org/entity/Q35963725

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Sonic hedgehog-dependent activ ...... nic hair follicle development.

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P2093

Andrzej A Dlugosz

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Chi-chung Hui

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Hong Fu

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Marina Grachtchouk

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Peter C W Kim

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Rong Mo

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P2860

Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb

Patched1 interacts with cyclin B1 to regulate cell cycle progression

Activating Smoothened mutations in sporadic basal-cell carcinoma

Induction of basal cell carcinomas and trichoepitheliomas in mice overexpressing GLI-1

Onset of keratin 17 expression coincides with the definition of major epithelial lineages during skin development

Mouse Gli1 mutants are viable but have defects in SHH signaling in combination with a Gli2 mutation

Specification of ventral neuron types is mediated by an antagonistic interaction between Shh and Gli3

Regulation of Gli2 and Gli3 activities by an amino-terminal repression domain: implication of Gli2 and Gli3 as primary mediators of Shh signaling

Molecular mechanisms regulating hair follicle development

Gene expression profiling leads to identification of GLI1-binding elements in target genes and a role for multiple downstream pathways in GLI1-induced cell transformation

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2

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17

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12533516

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195973

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