PrlA and PrlG suppressors reduce the requirement for signal sequence recognition
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Recognition of secretory proteins in Escherichia coli requires signals in addition to the signal sequence and slow folding.SPdb--a signal peptide database.The conformation of a signal peptide bound by Escherichia coli preprotein translocase SecAFolding and trimerization of signal sequence-less mature TolC in the cytoplasm of Escherichia coliProtein targeting to the bacterial cytoplasmic membrane.Signal peptides are allosteric activators of the protein translocase.PrlA4 prevents the rejection of signal sequence defective preproteins by stabilizing the SecA-SecY interaction during the initiation of translocation.The PrlA and PrlG phenotypes are caused by a loosened association among the translocase SecYEG subunits.Escherichia coli translocase: the unravelling of a molecular machine.Transport of preproteins by the accessory Sec system requires a specific domain adjacent to the signal peptideModeling the effects of prl mutations on the Escherichia coli SecY complex.Critical regions of secM that control its translation and secretion and promote secretion-specific secA regulation.Ring-like pore structures of SecA: implication for bacterial protein-conducting channels.Large-scale evolutionary analyses on SecB subunits of bacterial sec system.Carbon source-dependent synthesis of SecB, a cytosolic chaperone involved in protein translocation across Escherichia coli membranes.The bacterial Sec-translocase: structure and mechanism.Targeting of signal sequenceless proteins for export in Escherichia coli with altered protein translocase.A little help from my friends: quality control of presecretory proteins in bacteriaprl mutations in the Escherichia coli secG gene.Interactions that drive Sec-dependent bacterial protein transport.Tail-anchored membrane protein insertion into the endoplasmic reticulum.prlA suppressors in Escherichia coli relieve the proton electrochemical gradient dependency of translocation of wild-type precursors.Selective transport by SecA2: an expanding family of customized motor proteins.Investigating the SecY plug movement at the SecYEG translocation channel.SecB dependence of an exported protein is a continuum influenced by the characteristics of the signal peptide or early mature region.Suppression of signal sequence defects and azide resistance in Escherichia coli commonly result from the same mutations in secALeaderless polypeptides efficiently extracted from whole cells by osmotic shock.Differential translocation of protein precursors across SecY-deficient membranes of Escherichia coli: SecY is not obligatorily required for translocation of certain secretory proteins in vitro.The allele-specific synthetic lethality of prlA-prlG double mutants predicts interactive domains of SecY and SecE.Escherichia coli preprotein translocase.Defective translocation of a signal sequence mutant in a prlA4 suppressor strain of Escherichia coli.The Sec System: Protein Export in Escherichia coli.Conformational Changes That Coordinate the Activity of BamA and BamD Allowing β-Barrel Assembly.Both transmembrane domains of SecG contribute to signal sequence recognition by the Escherichia coli protein export machinery.Deregulation of the SecYEG translocation channel upon removal of the plug domain.Export and folding of signal-sequenceless Bacillus licheniformisβ-lactamase in Escherichia coli
P2860
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P2860
PrlA and PrlG suppressors reduce the requirement for signal sequence recognition
description
1994 nî lūn-bûn
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1994年の論文
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1994年学术文章
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1994年学术文章
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1994年学术文章
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1994年学术文章
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1994年學術文章
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name
PrlA and PrlG suppressors reduce the requirement for signal sequence recognition
@ast
PrlA and PrlG suppressors reduce the requirement for signal sequence recognition
@en
type
label
PrlA and PrlG suppressors reduce the requirement for signal sequence recognition
@ast
PrlA and PrlG suppressors reduce the requirement for signal sequence recognition
@en
prefLabel
PrlA and PrlG suppressors reduce the requirement for signal sequence recognition
@ast
PrlA and PrlG suppressors reduce the requirement for signal sequence recognition
@en
P2860
P1476
PrlA and PrlG suppressors reduce the requirement for signal sequence recognition
@en
P2093
A M Flower
R C Doebele
P2860
P304
P356
10.1128/JB.176.18.5607-5614.1994
P407
P577
1994-09-01T00:00:00Z