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Metabolic signatures of insulin resistance in 7,098 young adults.

Metabolic signatures of insulin resistance in 7,098 young adults.

http://www.wikidata.org/entity/Q35976648

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Metabolomics and Type 2 Diabetes: Translating Basic Research into Clinical Application The pathogenic role of persistent milk signaling in mTORC1- and milk-microRNA-driven type 2 diabetes mellitus TATN-1 mutations reveal a novel role for tyrosine as a metabolic signal that influences developmental decisions and longevity in Caenorhabditis elegans Prolonged sleep restriction induces changes in pathways involved in cholesterol metabolism and inflammatory responses.The Relationship between Branched-Chain Amino Acid Related Metabolomic Signature and Insulin Resistance: A Systematic Review Branched-chain amino acids in metabolic signalling and insulin resistance Intervention Trials with the Mediterranean Diet in Cardiovascular Prevention: Understanding Potential Mechanisms through Metabolomic Profiling Improved metabolic health alters host metabolism in parallel with changes in systemic xeno-metabolites of gut origin Metabolic signatures of adiposity in young adults: Mendelian randomization analysis and effects of weight change Mendelian randomization in cardiometabolic disease: challenges in evaluating causality.Pathophysiology and treatment of type 2 diabetes: perspectives on the past, present, and future.Random Survival Forest in practice: a method for modelling complex metabolomics data in time to event analysis.Activation of IRF1 in Human Adipocytes Leads to Phenotypes Associated with Metabolic Disease Urinary Metabolomics in Pediatric Obesity and NAFLD Identifies Metabolic Pathways/Metabolites Related to Dietary Habits and Gut-Liver Axis Perturbations.Gene-Diet Interactions in Type 2 Diabetes: The Chicken and Egg Debate Systems Epidemiology: A New Direction in Nutrition and Metabolic Disease Research Metabolomics in Prediabetes and Diabetes: A Systematic Review and Meta-analysis.Novel metabolic markers for the risk of diabetes development in American Indians.Effects of whole grain, fish and bilberries on serum metabolic profile and lipid transfer protein activities: a randomized trial (Sysdimet).Plasma and urine metabolic profiles are reflective of altered beta-oxidation in non-diabetic obese subjects and patients with type 2 diabetes mellitus.Relationship between insulin resistance and amino acids in women and men.Reliability of Serum Metabolites over a Two-Year Period: A Targeted Metabolomic Approach in Fasting and Non-Fasting Samples from EPIC.Plasma Free Amino Acid Profiles Predict Four-Year Risk of Developing Diabetes, Metabolic Syndrome, Dyslipidemia, and Hypertension in Japanese Population Association between insulin resistance and plasma amino acid profile in non-diabetic Japanese subjects Metabolomic Profiles of Body Mass Index in the Framingham Heart Study Reveal Distinct Cardiometabolic Phenotypes.Circulating metabolite predictors of glycemia in middle-aged men and women.Adipose Tissue Dysfunction and Altered Systemic Amino Acid Metabolism Are Associated with Non-Alcoholic Fatty Liver Disease Early Antenatal Prediction of Gestational Diabetes in Obese Women: Development of Prediction Tools for Targeted Intervention.Metabolic profiling of pregnancy: cross-sectional and longitudinal evidence.Global deletion of BCATm increases expression of skeletal muscle genes associated with protein turnover Metabolomics in childhood diabetes.Tyrosine Is Associated with Insulin Resistance in Longitudinal Metabolomic Profiling of Obese Children.Targeted metabolomics finds its mark in diabetes research Branched-chain amino acids alter neurobehavioral function in rats Branched-chain and aromatic amino acids are predictors of insulin resistance in young adults Weight loss is associated with plasma free amino acid alterations in subjects with metabolic syndrome.Regulation of adipose branched-chain amino acid catabolism enzyme expression and cross-adipose amino acid flux in human obesity.Circulating lysophosphatidylcholines are markers of a metabolically benign nonalcoholic fatty liver Metabolic Characterization of a Rare Genetic Variation Within APOC3 and Its Lipoprotein Lipase-Independent Effects.Metabolomics in diabetic complications.

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Metabolic signatures of insulin resistance in 7,098 young adults.

http://www.wikidata.org/entity/Q35976648

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2012年学术文章

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2012年学术文章

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2012年學術文章

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Metabolic signatures of insulin resistance in 7,098 young adults.

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Metabolic signatures of insulin resistance in 7,098 young adults.

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Jorma S Viikari

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Markku J Savolainen

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Olli T Raitakari

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Pasi Soininen

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Tapani Rönnemaa

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Taru Tukiainen

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Tuija Tammelin

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P2860

Discovery of sexual dimorphisms in metabolic and genetic biomarkers

Common missense variant in the glucokinase regulatory protein gene is associated with increased plasma triglyceride and C-reactive protein but lower fasting glucose concentrations

Genome-wide association analysis of metabolic traits in a birth cohort from a founder population

Homeostasis model assessment: insulin resistance and ?-cell function from fasting plasma glucose and insulin concentrations in man

The human plasma lipidome

A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance

Human metabolic individuality in biomedical and pharmaceutical research

Genome-wide association study identifies multiple loci influencing human serum metabolite levels

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

Mechanisms linking obesity to insulin resistance and type 2 diabetes

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Marjo-Riitta Järvelin

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