about
The influence of locked nucleic acid residues on the thermodynamic properties of 2'-O-methyl RNA/RNA heteroduplexesIntercalator conjugates of pyrimidine locked nucleic acid-modified triplex-forming oligonucleotides: improving DNA binding properties and reaching cellular activities.Advanced In vivo Use of CRISPR/Cas9 and Anti-sense DNA Inhibition for Gene Manipulation in the BrainNot so pseudo anymore: pseudogenes as therapeutic targetsThe lncRNA VELUCT strongly regulates viability of lung cancer cells despite its extremely low abundance.Functionalized 2'-amino-alpha-L-LNA: directed positioning of intercalators for DNA targeting.Microparticle-based delivery of oxytocin receptor antisense DNA in the medial amygdala blocks social recognition in female mice.Modulating Anti-MicroRNA-21 Activity and Specificity Using Oligonucleotide Derivatives and Length Optimization.Biophysical studies of DNA modified with conformationally constrained nucleotides: comparison of 2'-exo (north) and 3'-exo (south) 'locked' templatesIn vivo screening of modified siRNAs for non-specific antiviral effect in a small fish model: number and localization in the strands are importantComparative crystallization and preliminary X-ray diffraction studies of locked nucleic acid and RNA stems of a tenascin C-binding aptamer.Application of locked nucleic acids to improve aptamer in vivo stability and targeting functionPervasive transcription of a herpesvirus genome generates functionally important RNAs.Solution structure of a dsDNA:LNA triplex.Hydroxyproline-based DNA mimics provide an efficient gene silencing in vitro and in vivo.Quantum mechanical studies of DNA and LNA.Systematic analysis of enzymatic DNA polymerization using oligo-DNA templates and triphosphate analogs involving 2',4'-bridged nucleosides.Antisense tools for functional studies of human Argonaute proteins.A bridged nucleic acid, 2',4'-BNA COC: synthesis of fully modified oligonucleotides bearing thymine, 5-methylcytosine, adenine and guanine 2',4'-BNA COC monomers and RNA-selective nucleic-acid recognitionPeptide-mediated Cell and In Vivo Delivery of Antisense Oligonucleotides and siRNA.Locked nucleic acid and aptamers.Inhibition of EZH2 triggers the tumor suppressive miR-29b network in multiple myeloma.Single Locked Nucleic Acid-Enhanced Nanopore Genetic Discrimination of Pathogenic Serotypes and Cancer Driver Mutations.
P2860
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P2860
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
LNA-antisense rivals siRNA for gene silencing.
@ast
LNA-antisense rivals siRNA for gene silencing.
@en
type
label
LNA-antisense rivals siRNA for gene silencing.
@ast
LNA-antisense rivals siRNA for gene silencing.
@en
prefLabel
LNA-antisense rivals siRNA for gene silencing.
@ast
LNA-antisense rivals siRNA for gene silencing.
@en
P1476
LNA-antisense rivals siRNA for gene silencing.
@en
P2093
Jan Stenvang Jepsen
Jesper Wengel
P304
P577
2004-03-01T00:00:00Z