RNA surveillance is required for endoplasmic reticulum homeostasis. - Wikidata - wikimedia - TriplyDB

RNA surveillance is required for endoplasmic reticulum homeostasis.

RNA surveillance is required for endoplasmic reticulum homeostasis.

http://www.wikidata.org/entity/Q35991558

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Mechanism and regulation of the nonsense-mediated decay pathway The circadian clock regulates autophagy directly through the nuclear hormone receptor Nr1d1/Rev-erbα and indirectly via Cebpb/(C/ebpβ) in zebrafish.Nonsense-Mediated mRNA Decay: Degradation of Defective Transcripts Is Only Part of the Story Organizing principles of mammalian nonsense-mediated mRNA decay High-resolution profiling of NMD targets in yeast reveals translational fidelity as a basis for substrate selection.The unfolded protein response affects readthrough of premature termination codons Activation of the endoplasmic reticulum unfolded protein response by lipid disequilibrium without disturbed proteostasis in vivo Identification of SMG6 cleavage sites and a preferred RNA cleavage motif by global analysis of endogenous NMD targets in human cells.The unfolded protein response is shaped by the NMD pathway Endoplasmic reticulum stress preconditioning attenuates methylmercury-induced cellular damage by inducing favorable stress responses.Inhibition of SMG-8, a subunit of SMG-1 kinase, ameliorates nonsense-mediated mRNA decay-exacerbated mutant phenotypes without cytotoxicity.IRE1: ER stress sensor and cell fate executor.Uncovering buffered pleiotropy: a genome-scale screen for mel-28 genetic interactors in Caenorhabditis elegans.Molecular signal networks and regulating mechanisms of the unfolded protein response.Nonsense-mediated mRNA decay: from mechanistic insights to impacts on human health.Wnt-signaling and planar cell polarity genes regulate axon guidance along the anteroposterior axis in C. elegans.Endoplasmic reticulum quality control in cancer: Friend or foe.Proteostasis control by the unfolded protein response Stress and the nonsense-mediated RNA decay pathway.Interaction between quality control systems for ER protein folding and RNA biogenesis.Proteomic Analysis Reveals Branch-specific Regulation of the Unfolded Protein Response by Nonsense-mediated mRNA Decay.NeuCode Labeling in Nematodes: Proteomic and Phosphoproteomic Impact of Ascaroside Treatment in Caenorhabditis elegans.RNA metabolism: putting the brake on the UPR.Erratum: Proteostasis control by the unfolded protein response.Inhibition of nonsense-mediated RNA decay by ER stress.Endoplasmic Reticulum Stress in Mice Increases Hepatic Expression of Genes Carrying a Premature Termination Codon via a Nutritional Status-Independent GRP78-Dependent Mechanism.Nonsense-mediated mRNA decay: a 'nonsense' pathway makes sense in stem cell biology.Oncoprotein AEG-1 is an Endoplasmic Reticulum RNA Binding Protein Whose Interactome is Enriched In Organelle Resident Protein-Encoding mRNAs.The loss of SMG1 causes defects in quality control pathways in Physcomitrella patens.Targeting the spliceosome for cutaneous squamous cell carcinoma therapy: a role for c-MYC and wild-type p53 in determining the degree of tumour selectivity.Functional Interactions Between /S6K, /Notch, and Regulators of Fertility and Germline Stem Cell Maintenance

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RNA surveillance is required for endoplasmic reticulum homeostasis.

http://www.wikidata.org/entity/Q35991558

description

2012 nî lūn-bûn

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2012年の論文

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年學術文章

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2012年學術文章

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2012年學術文章

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name

RNA surveillance is required for endoplasmic reticulum homeostasis.

@ast

RNA surveillance is required for endoplasmic reticulum homeostasis.

@en

type

label

RNA surveillance is required for endoplasmic reticulum homeostasis.

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RNA surveillance is required for endoplasmic reticulum homeostasis.

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prefLabel

RNA surveillance is required for endoplasmic reticulum homeostasis.

@ast

RNA surveillance is required for endoplasmic reticulum homeostasis.

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PNAS.1110589109

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Proceedings of the National Academy of Sciences of the United States of America

P1476

RNA surveillance is required for endoplasmic reticulum homeostasis.

@en

P2093

Jaeseok Han

http://www.w3.org/2001/XMLSchema#string

Kenjiro Sakaki

http://www.w3.org/2001/XMLSchema#string

Melinda R DeSantis

http://www.w3.org/2001/XMLSchema#string

Mon Xiong

http://www.w3.org/2001/XMLSchema#string

Randal J Kaufman

http://www.w3.org/2001/XMLSchema#string

Sawako Yoshina

http://www.w3.org/2001/XMLSchema#string

Xiaohua Shen

http://www.w3.org/2001/XMLSchema#string

P2860

Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress

ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs

Complementary signaling pathways regulate the unfolded protein response and are required for C. elegans development

Phosphorylation of hUPF1 induces formation of mRNA surveillance complexes containing hSMG-5 and hSMG-7

Binding of a novel SMG-1-Upf1-eRF1-eRF3 complex (SURF) to the exon junction complex triggers Upf1 phosphorylation and nonsense-mediated mRNA decay

SMG6 is the catalytic endonuclease that cleaves mRNAs containing nonsense codons in metazoan

SMG6 promotes endonucleolytic cleavage of nonsense mRNA in human cells

Upf1 phosphorylation triggers translational repression during nonsense-mediated mRNA decay

The genetics of Caenorhabditis elegans

IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response

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8079-8084

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endoplasmic reticulum

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