Tau alteration and neuronal degeneration in tauopathies: mechanisms and models.
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Hyperphosphorylation of microtubule-associated protein tau: a promising therapeutic target for Alzheimer diseaseFluid Biomarkers in Clinical Trials of Alzheimer's Disease TherapeuticsAbnormal interaction between the mitochondrial fission protein Drp1 and hyperphosphorylated tau in Alzheimer's disease neurons: implications for mitochondrial dysfunction and neuronal damageMelatonin in Alzheimer's disease and other neurodegenerative disordersThe Ubiquitin-Proteasome System and Molecular Chaperone Deregulation in Alzheimer's DiseaseAge-dependent changes in neuronal distribution of CacyBP/SIP: comparison to tubulin and the tau proteinMammalian target of rapamycin (mTor) mediates tau protein dyshomeostasis: implication for Alzheimer diseaseCan zebrafish be used as animal model to study Alzheimer's disease?MSUT2 is a determinant of susceptibility to tau neurotoxicityHuntingtin interacting protein HYPK is intrinsically unstructured.Tau-directed drug discovery for Alzheimer's disease and related tauopathies: a focus on tau assembly inhibitors.Monte carlo simulations of tau proteins: effect of phosphorylation.Strategies for diminishing katanin-based loss of microtubules in tauopathic neurodegenerative diseases.Tau mislocalization to dendritic spines mediates synaptic dysfunction independently of neurodegeneration.Hypoxia alters expression of zebrafish microtubule-associated protein tau (mapta, maptb) gene transcripts.Bimolecular fluorescence complementation; lighting-up tau-tau interaction in living cells.Abnormal tau, mitochondrial dysfunction, impaired axonal transport of mitochondria, and synaptic deprivation in Alzheimer's diseaseTau splicing and the intricacies of dementia.Potential natural products for Alzheimer's disease: targeted search using the internal ribosome entry site of tau and amyloid-β precursor protein.A Stochastic Multiscale Model That Explains the Segregation of Axonal Microtubules and Neurofilaments in Neurological Diseases.Transgenic mouse and cell culture models demonstrate a lack of mechanistic connection between endoplasmic reticulum stress and tau dysfunction.Hypothermia-induced hyperphosphorylation: a new model to study tau kinase inhibitors.Progression of Regional Microstructural Degeneration in Parkinson's Disease: A Multicenter Diffusion Tensor Imaging StudyThe synaptic accumulation of hyperphosphorylated tau oligomers in Alzheimer disease is associated with dysfunction of the ubiquitin-proteasome system.Ageing and neuronal vulnerability.Tau phosphorylation, aggregation, and cell toxicityA Novel Mechanism of Spine Damages in Stroke via DAPK1 and Tau.In vivo mouse imaging and spectroscopy in drug discovery.Knock-out and transgenic mouse models of tauopathies.Mechanisms of neurodegenerative diseases: insights from live cell imaging.Conditionally inducible tau mice--designing a better mouse model of neurodegenerative diseases.The thioredoxin-like protein rod-derived cone viability factor (RdCVFL) interacts with TAU and inhibits its phosphorylation in the retina.Trends in the molecular pathogenesis and clinical therapeutics of common neurodegenerative disordersA novel tau mutation, p.K317N, causes globular glial tauopathyPercutaneous radiofrequency thermocoagulation for trigeminal neuralgia using neuronavigation-guided puncture from a mandibular angle.The rat as an animal model of Alzheimer's disease.Animal models of human amyloidoses: are transgenic mice worth the time and trouble?Frontotemporal lobar degeneration: current perspectives.Amyloid-β and hyperphosphorylated tau synergy drives metabolic decline in preclinical Alzheimer's disease.Advances in tau-focused drug discovery for Alzheimer's disease and related tauopathies.
P2860
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P2860
Tau alteration and neuronal degeneration in tauopathies: mechanisms and models.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Tau alteration and neuronal degeneration in tauopathies: mechanisms and models.
@ast
Tau alteration and neuronal degeneration in tauopathies: mechanisms and models.
@en
type
label
Tau alteration and neuronal degeneration in tauopathies: mechanisms and models.
@ast
Tau alteration and neuronal degeneration in tauopathies: mechanisms and models.
@en
prefLabel
Tau alteration and neuronal degeneration in tauopathies: mechanisms and models.
@ast
Tau alteration and neuronal degeneration in tauopathies: mechanisms and models.
@en
P2093
P1476
Tau alteration and neuronal degeneration in tauopathies: mechanisms and models.
@en
P2093
Monika Hundelt
Neelam Shahani
Roland Brandt
P304
P356
10.1016/J.BBADIS.2004.06.018
P407
P577
2005-01-01T00:00:00Z