Mammalian target of rapamycin (mTor) mediates tau protein dyshomeostasis: implication for Alzheimer disease
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Milk--A Nutrient System of Mammalian Evolution Promoting mTORC1-Dependent TranslationThe pathogenic role of persistent milk signaling in mTORC1- and milk-microRNA-driven type 2 diabetes mellitusIn vivo AAV1 transduction with hRheb(S16H) protects hippocampal neurons by BDNF productionGenetic reduction of mammalian target of rapamycin ameliorates Alzheimer's disease-like cognitive and pathological deficits by restoring hippocampal gene expression signatureActivation of extracellular regulated kinase and mechanistic target of rapamycin pathway in focal cortical dysplasia.The mammalian target of rapamycin at the crossroad between cognitive aging and Alzheimer's disease.Cotinine halts the advance of Alzheimer's disease-like pathology and associated depressive-like behavior in Tg6799 miceTaking aim at Alzheimer's disease through the mammalian target of rapamycinAbnormal serine phosphorylation of insulin receptor substrate 1 is associated with tau pathology in Alzheimer's disease and tauopathies.Functional role of RNA polymerase II and P70 S6 kinase in KCl withdrawal-induced cerebellar granule neuron apoptosis.Hippocampal endosomal, lysosomal, and autophagic dysregulation in mild cognitive impairment: correlation with aβ and tau pathologyEffect of treadmill exercise on PI3K/AKT/mTOR, autophagy, and Tau hyperphosphorylation in the cerebral cortex of NSE/htau23 transgenic miceMilk: an epigenetic amplifier of FTO-mediated transcription? Implications for Western diseases.APP controls the formation of PI(3,5)P(2) vesicles through its binding of the PIKfyve complexRho Kinase Inhibition as a Therapeutic for Progressive Supranuclear Palsy and Corticobasal DegenerationAutophagic and lysosomal defects in human tauopathies: analysis of post-mortem brain from patients with familial Alzheimer disease, corticobasal degeneration and progressive supranuclear palsy.Rapamycin suppresses brain aging in senescence-accelerated OXYS rats.Long-term caloric restriction in ApoE-deficient mice results in neuroprotection via Fgf21-induced AMPK/mTOR pathway.Targeting the mTOR signaling network for Alzheimer's disease therapy.Diabetic retinopathy: loss of neuroretinal adaptation to the diabetic metabolic environment.Advances in quantitative structure-activity relationship models of anti-Alzheimer's agents.mTOR in Brain Physiology and Pathologies.Targeting mTOR to reduce Alzheimer-related cognitive decline: from current hits to future therapies.High glucose induces formation of tau hyperphosphorylation via Cav-1-mTOR pathway: A potential molecular mechanism for diabetes-induced cognitive dysfunction.Radiosynthesis of [18F]ATPFU: a potential PET ligand for mTOR.Milk's Role as an Epigenetic Regulator in Health and Diseaseμ-Opioid receptor attenuates Aβ oligomers-induced neurotoxicity through mTOR signaling.Dual mTORC1/mTORC2 blocker as a possible therapy for tauopathy in cellular model.Wogonin increases β-amyloid clearance and inhibits tau phosphorylation via inhibition of mammalian target of rapamycin: potential drug to treat Alzheimer's disease.Action of thyroxine on the survival and neurite maintenance of cerebellar granule neurons in culture.mTOR-mediated hyperphosphorylation of tau in the hippocampus is involved in cognitive deficits in streptozotocin-induced diabetic mice.FoxO proteins in the nervous system.Intranasal rapamycin ameliorates Alzheimer-like cognitive decline in a mouse model of Down syndrome
P2860
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P2860
Mammalian target of rapamycin (mTor) mediates tau protein dyshomeostasis: implication for Alzheimer disease
description
2013 nî lūn-bûn
@nan
2013 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Mammalian target of rapamycin ...... lication for Alzheimer disease
@ast
Mammalian target of rapamycin ...... lication for Alzheimer disease
@en
type
label
Mammalian target of rapamycin ...... lication for Alzheimer disease
@ast
Mammalian target of rapamycin ...... lication for Alzheimer disease
@en
prefLabel
Mammalian target of rapamycin ...... lication for Alzheimer disease
@ast
Mammalian target of rapamycin ...... lication for Alzheimer disease
@en
P2093
P2860
P50
P356
P1476
Mammalian target of rapamycin ...... lication for Alzheimer disease
@en
P2093
Chunxia Li
Haiyan Zhang
Jin-Jing Pei
Peter Filipcik
Shaohua Xu
Xinying Ji
Zhizhong Guan
P2860
P304
15556-15570
P356
10.1074/JBC.M112.435123
P407
P577
2013-04-12T00:00:00Z