The zinc finger transcription factor Growth factor independence 1 (Gfi1).
about
Gfi1 coordinates epigenetic repression of p21Cip/WAF1 by recruitment of histone lysine methyltransferase G9a and histone deacetylase 1A role of Miz-1 in Gfi-1-mediated transcriptional repression of CDKN1AZinc finger protein Gfi1 controls the endotoxin-mediated Toll-like receptor inflammatory response by antagonizing NF-kappaB p65Growth factor independence-1 (Gfi-1) plays a role in mediating specific granule deficiency (SGD) in a patient lacking a gene-inactivating mutation in the C/EBPepsilon geneDirect transcriptional repression of the genes encoding the zinc-finger proteins Gfi1b and Gfi1 by Gfi1bFrom cytopenia to leukemia: the role of Gfi1 and Gfi1b in blood formationAuxiliary splice factor U2AF26 and transcription factor Gfi1 cooperate directly in regulating CD45 alternative splicingGfi1b alters histone methylation at target gene promoters and sites of gamma-satellite containing heterochromatinGfi1Cre mice have early onset progressive hearing loss and induce recombination in numerous inner ear non-hair cells.Gfi1 and Gfi1b act equivalently in haematopoiesis, but have distinct, non-overlapping functions in inner ear developmentA genetic screen in Drosophila for genes interacting with senseless during neuronal development identifies the importin moleskinGlobal analysis of alternative splicing during T-cell activation.Molecular mechanism of upregulation of survivin transcription by the AT-rich DNA-binding ligand, Hoechst33342: evidence for survivin involvement in drug resistance.Evidence that growth factor independence 1b regulates dormancy and peripheral blood mobilization of hematopoietic stem cells.Transcriptional hallmarks of Noonan syndrome and Noonan-like syndrome with loose anagen hair.Gfi-1 inhibits the expression of eosinophil major basic protein (MBP) during G-CSF-induced neutrophilic differentiationGfi-1 represses CDKN2B encoding p15INK4B through interaction with Miz-1.Neutrophils mediate antibody-induced antitumor effects in mice.Formation of IL-7Ralphahigh and IL-7Ralphalow CD8 T cells during infection is regulated by the opposing functions of GABPalpha and Gfi-1.Interleukin and interleukin receptor diversity: role of alternative splicing.Transcriptional control of early T and B cell developmental choicesAcute myeloid leukemia cells polarize macrophages towards a leukemia supporting state in a Growth factor independence 1 dependent manner.ETO-2 associates with SCL in erythroid cells and megakaryocytes and provides repressor functions in erythropoiesis.Increased CCAAT enhancer-binding protein epsilon (C/EBPepsilon) expression and premature apoptosis in myeloid cells expressing Gfi-1 N382S mutant associated with severe congenital neutropenia.Zebrafish reward mutants reveal novel transcripts mediating the behavioral effects of amphetamine.Growth factor independence 1 protects hematopoietic stem cells against apoptosis but also prevents the development of a myeloproliferative-like disease.Enforced GFI1 expression impedes human and murine leukemic cell growth.
P2860
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P2860
The zinc finger transcription factor Growth factor independence 1 (Gfi1).
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
The zinc finger transcription factor Growth factor independence 1 (Gfi1).
@ast
The zinc finger transcription factor Growth factor independence 1 (Gfi1).
@en
type
label
The zinc finger transcription factor Growth factor independence 1 (Gfi1).
@ast
The zinc finger transcription factor Growth factor independence 1 (Gfi1).
@en
prefLabel
The zinc finger transcription factor Growth factor independence 1 (Gfi1).
@ast
The zinc finger transcription factor Growth factor independence 1 (Gfi1).
@en
P1476
The zinc finger transcription factor Growth factor independence 1 (Gfi1).
@en
P2093
Tarik Möröy
P304
P356
10.1016/J.BIOCEL.2004.08.011
P577
2005-03-01T00:00:00Z