Targeting survivin and p53 in pediatric acute lymphoblastic leukemia.
about
Localization and upregulation of survivin in cancer health disparities: a clinical perspectiveSurvivin selective inhibitor YM155 induce apoptosis in SK-NEP-1 Wilms tumor cells.Bortezomib-based chemotherapy regimens can improve response in newly diagnosed multiple myeloma patients with bcl-2 and survivin overexpression.A phase I study of EZN-3042, a novel survivin messenger ribonucleic acid (mRNA) antagonist, administered in combination with chemotherapy in children with relapsed acute lymphoblastic leukemia (ALL): a report from the therapeutic advances in childhoYM155 potently kills acute lymphoblastic leukemia cells through activation of the DNA damage pathwayAML sensitivity to YM155 is modulated through AKT and Mcl-1.TPEN induces apoptosis independently of zinc chelator activity in a model of acute lymphoblastic leukemia and ex vivo acute leukemia cells through oxidative stress and mitochondria caspase-3- and AIF-dependent pathways.Pathway-based network modeling finds hidden genes in shRNA screen for regulators of acute lymphoblastic leukemia.Arsenic trioxide induces apoptosis in B-cell chronic lymphocytic leukemic cells through down-regulation of survivin via the p53-dependent signaling pathway.Inhibitor of apoptosis proteins in pediatric leukemia: molecular pathways and novel approaches to therapy.Targeted nanoparticles for pediatric leukemia therapy.Survivin splice variants and their diagnostic significance.Effects of YM155 on survivin levels and viability in neuroblastoma cells with acquired drug resistance.Kaposi's sarcoma-associated herpesvirus-encoded LANA contributes to viral latent replication by activating phosphorylation of survivin.Small-molecule inhibition of CBP/catenin interactions eliminates drug-resistant clones in acute lymphoblastic leukemia.Flavokawain B inhibits the growth of acute lymphoblastic leukemia cells via p53 and caspase-dependent mechanisms.Anti-leukemic response of a NSAID, tolfenamic acid.CBP/Catenin antagonists: Targeting LSCs' Achilles heel.Bufalin induces the apoptosis of acute promyelocytic leukemia cells via the downregulation of survivin expression.Dual targeting of MDM2 and BCL2 as a therapeutic strategy in neuroblastoma.Fish-oil-derived eicosapentaenoic acid decreases survivin expression and induces wt-p53 accumulation with caspase-3 activation in acute lymphoblastic leukemia cells.Fish-Oil-Derived DHA-mediated Enhancement of Apoptosis in Acute Lymphoblastic Leukemia Cells is Associated with Accumulation of p53, Downregulation of Survivin, and Caspase-3 Activation.Targeting the proliferative and chemoresistant compartment in chronic lymphocytic leukemia by inhibiting survivin protein.New targeted therapies for relapsed pediatric acute lymphoblastic leukemia.Evaluation of survivin immunoexpression in the differentiation of high- and low-grade breast ductal carcinoma in situ.
P2860
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P2860
Targeting survivin and p53 in pediatric acute lymphoblastic leukemia.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Targeting survivin and p53 in pediatric acute lymphoblastic leukemia.
@ast
Targeting survivin and p53 in pediatric acute lymphoblastic leukemia.
@en
type
label
Targeting survivin and p53 in pediatric acute lymphoblastic leukemia.
@ast
Targeting survivin and p53 in pediatric acute lymphoblastic leukemia.
@en
prefLabel
Targeting survivin and p53 in pediatric acute lymphoblastic leukemia.
@ast
Targeting survivin and p53 in pediatric acute lymphoblastic leukemia.
@en
P2860
P50
P356
P1433
P1476
Targeting survivin and p53 in pediatric acute lymphoblastic leukemia
@en
P2093
P2860
P2888
P304
P356
10.1038/LEU.2011.249
P577
2011-09-30T00:00:00Z