The zinc-finger protein MAZR is part of the transcription factor network that controls the CD4 versus CD8 lineage fate of double-positive thymocytes.
about
Transcriptional control of CD4 and CD8 coreceptor expression during T cell developmentThe epigenetic landscape of lineage choice: lessons from the heritability of CD4 and CD8 expressionKAP1 regulates gene networks controlling T-cell development and responsiveness.The transcription factors Thpok and LRF are necessary and partly redundant for T helper cell differentiationAltered development of NKT cells, γδ T cells, CD8 T cells and NK cells in a PLZF deficient patient.A ThPOK-LRF transcriptional node maintains the integrity and effector potential of post-thymic CD4+ T cells.Transcriptional repressors, corepressors and chromatin modifying enzymes in T cell development.The dosage of Patz1 modulates reprogramming process.The transcription factor MAZR preferentially acts as a transcriptional repressor in mast cells and plays a minor role in the regulation of effector functions in response to FcεRI stimulation.CD4(+) T cell lineage integrity is controlled by the histone deacetylases HDAC1 and HDAC2.TOX is required for development of the CD4 T cell lineage gene program.POK/ZBTB proteins: an emerging family of proteins that regulate lymphoid development and functionDecision checkpoints in the thymus.The enigma of CD4-lineage specification.Transcriptional reprogramming of mature CD4⁺ helper T cells generates distinct MHC class II-restricted cytotoxic T lymphocytes.PATZ1 is a target of miR-29b that is induced by Ha-Ras oncogene in rat thyroid cells.What Happens in the Thymus Does Not Stay in the Thymus: How T Cells Recycle the CD4+-CD8+ Lineage Commitment Transcriptional Circuitry To Control Their Function.Maintaining CD4-CD8 lineage integrity in T cells: where plasticity serves versatilityCD4-CD8 differentiation in the thymus: connecting circuits and building memoriesMutual expression of the transcription factors Runx3 and ThPOK regulates intestinal CD4⁺ T cell immunity.Vitamin C promotes maturation of T-cells.PATZ1 interacts with p53 and regulates expression of p53-target genes enhancing apoptosis or cell survival based on the cellular context.CD4 CTL: living up to the challenge.Fighting Viral Infections and Virus-Driven Tumors with Cytotoxic CD4+ T Cells.Heritable Gene Regulation in the CD4:CD8 T Cell Lineage Choice.The network of transcription factors that underlie the CD4 versus CD8 lineage decision.Development of PLZF-expressing innate T cellsThe BTB-ZF family of transcription factors: key regulators of lineage commitment and effector function development in the immune system.Transcriptional control of T-cell development.The BTB-ZF transcription factors.From inception to output, Tcf1 and Lef1 safeguard development of T cells and innate immune cells.POZ-, AT-hook-, and zinc finger-containing protein (PATZ) interacts with human oncogene B cell lymphoma 6 (BCL6) and is required for its negative autoregulation.PATZ1 Is a DNA Damage-Responsive Transcription Factor That Inhibits p53 Function.Views on helper/cytotoxic lineage choice from a bottom-up approach.Regulation of hematopoietic development by ZBTB transcription factors.Tissue adaptation: Implications for gut immunity and tolerance.The transcription factor Zbtb32 controls the proliferative burst of virus-specific natural killer cells responding to infection.Priming of lineage-specifying genes by Bcl11b is required for lineage choice in post-selection thymocytes.Down-regulation of oestrogen receptor-β associates with transcriptional co-regulator PATZ1 delocalization in human testicular seminomas.The POZ/BTB and AT-Hook Containing Zinc Finger 1 (PATZ1) Transcription Regulator: Physiological Functions and Disease Involvement.
P2860
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P2860
The zinc-finger protein MAZR is part of the transcription factor network that controls the CD4 versus CD8 lineage fate of double-positive thymocytes.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
2010年學術文章
@zh
2010年學術文章
@zh-hant
name
The zinc-finger protein MAZR i ...... of double-positive thymocytes.
@ast
The zinc-finger protein MAZR i ...... of double-positive thymocytes.
@en
type
label
The zinc-finger protein MAZR i ...... of double-positive thymocytes.
@ast
The zinc-finger protein MAZR i ...... of double-positive thymocytes.
@en
prefLabel
The zinc-finger protein MAZR i ...... of double-positive thymocytes.
@ast
The zinc-finger protein MAZR i ...... of double-positive thymocytes.
@en
P2093
P2860
P356
P1433
P1476
The zinc-finger protein MAZR i ...... of double-positive thymocytes.
@en
P2093
Alexandra Schebesta
Ichiro Taniuchi
Ivan Bilic
Matthias Hombauer
Shinya Sakaguchi
Yoshinori Naoe
P2860
P304
P356
10.1038/NI.1860
P407
P577
2010-04-11T00:00:00Z