Sequence variation in promoter of Ica1 gene, which encodes protein implicated in type 1 diabetes, causes transcription factor autoimmune regulator (AIRE) to increase its binding and down-regulate expression.
about
Bioengineering Thymus Organoids to Restore Thymic Function and Induce Donor-Specific Immune Tolerance to Allografts.Immunogenetics of type 1 diabetes mellitusLupus pathobiology based on genomics.Novel and rare functional genomic variants in multiple autoimmune syndrome and Sjögren's syndrome.Islet autoantigens: structure, function, localization, and regulation.Compromised central tolerance of ICA69 induces multiple organ autoimmunity.Advances in our understanding of the pathophysiology of Type 1 diabetes: lessons from the NOD mouse.The dual role of autoimmune regulator in maintaining normal expression level of tissue-restricted autoantigen in the thymus: A modeling investigation.
P2860
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P2860
Sequence variation in promoter of Ica1 gene, which encodes protein implicated in type 1 diabetes, causes transcription factor autoimmune regulator (AIRE) to increase its binding and down-regulate expression.
description
2012 nî lūn-bûn
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2012年の論文
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2012年論文
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2012年論文
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2012年論文
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2012年論文
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2012年論文
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2012年论文
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2012年论文
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name
Sequence variation in promoter ...... and down-regulate expression.
@ast
Sequence variation in promoter ...... and down-regulate expression.
@en
type
label
Sequence variation in promoter ...... and down-regulate expression.
@ast
Sequence variation in promoter ...... and down-regulate expression.
@en
prefLabel
Sequence variation in promoter ...... and down-regulate expression.
@ast
Sequence variation in promoter ...... and down-regulate expression.
@en
P2093
P2860
P356
P1476
Sequence variation in promoter ...... and down-regulate expression.
@en
P2093
Alberto Pugliese
Giuliana Trucco
Massimo Pietropaolo
Massimo Trucco
Michael O Palumbo
Michael P Morran
Michele Solimena
Nick Giannoukakis
Praveen Sethupathy
Samantha M Bonner
P2860
P304
17882-17893
P356
10.1074/JBC.M111.319020
P407
P577
2012-03-24T00:00:00Z