The contractile apparatus as a target for drugs against heart failure: interaction of levosimendan, a calcium sensitiser, with cardiac troponin c.
about
Levosimendan: current data, clinical use and future developmentA structural and functional perspective into the mechanism of Ca2+-sensitizers that target the cardiac troponin complexStructure of trans -Resveratrol in Complex with the Cardiac Regulatory Protein Troponin CComputer-aided drug discovery approach finds calcium sensitizer of cardiac troponinDefining the binding site of levosimendan and its analogues in a regulatory cardiac troponin C-troponin I complexTrial watch: Cardiac glycosides and cancer therapyComparison of Levosimendan versus Dobutamine in Patients with Moderate to Severe Left Ventricular Dysfunction Undergoing Off-pump Coronary Artery Bypass Grafting: A Randomized Prospective Study.An efficacy and mechanism evaluation study of Levosimendan for the Prevention of Acute oRgan Dysfunction in Sepsis (LeoPARDS): protocol for a randomized controlled trial.Beneficial effects of SR33805 in failing myocardium.Use of levosimendan in patients with heart failure in different settings: case reports and treatment guidance.Structural and functional consequences of the cardiac troponin C L48Q Ca(2+)-sensitizing mutation.Myocardial regulatory proteins and heart failure.Interaction of cardiac troponin with cardiotonic drugs: a structural perspective.Sarcomere neutralization in inherited cardiomyopathy: small-molecule proof-of-concept to correct hyper-Ca2+-sensitive myofilamentsSingle histidine button in cardiac troponin I sustains heart performance in response to severe hypercapnic respiratory acidosis in vivo.Cardiac resynchronization sensitizes the sarcomere to calcium by reactivating GSK-3β.Sarcomere control mechanisms and the dynamics of the cardiac cycle.Inotropes and inodilators for acute heart failure: sarcomere active drugs in focus.Probing the mechanism of cardiovascular drugs using a covalent levosimendan analog.Levosimendan improves calcium sensitivity of diaphragm muscle fibres from a rat model of heart failureAbsence of mitochondrial activation during levosimendan inotropic action in perfused paced guinea pig hearts as demonstrated by modular control analysis.Levosimendan enhances force generation of diaphragm muscle from patients with chronic obstructive pulmonary disease.Levosimendan improves cardiac function and myocardial efficiency in rats with right ventricular failure.Na+/K+ ATPase activity promotes invasion of endocrine resistant breast cancer cells.Acute liver failure with extreme hyperbilirubinemia secondary to endocarditis-related severe mitral and tricuspid regurgitation: a challenge and an opportunity for surgeons.Differential Hemodynamic Effects of Levosimendan in a Porcine Model of Neonatal Hypoxia-Reoxygenation
P2860
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P2860
The contractile apparatus as a target for drugs against heart failure: interaction of levosimendan, a calcium sensitiser, with cardiac troponin c.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
The contractile apparatus as a ...... iser, with cardiac troponin c.
@ast
The contractile apparatus as a ...... iser, with cardiac troponin c.
@en
type
label
The contractile apparatus as a ...... iser, with cardiac troponin c.
@ast
The contractile apparatus as a ...... iser, with cardiac troponin c.
@en
prefLabel
The contractile apparatus as a ...... iser, with cardiac troponin c.
@ast
The contractile apparatus as a ...... iser, with cardiac troponin c.
@en
P1476
The contractile apparatus as a ...... iser, with cardiac troponin c.
@en
P2093
R John Solaro
P304
P356
10.1023/B:MCBI.0000049141.37823.19
P577
2004-11-01T00:00:00Z
P6179
1031295668