EPO modulation of cell-cycle regulatory genes, and cell division, in primary bone marrow erythroblasts
about
RHEX, a novel regulator of human erythroid progenitor cell expansion and erythroblast developmentThe progress of early growth response factor 1 and leukemiaIneffective erythropoiesis in β -thalassemiaEndothelial Cell-Selective Adhesion Molecule Expression in Hematopoietic Stem/Progenitor Cells Is Essential for Erythropoiesis Recovery after Bone Marrow InjuryDefining an EPOR- regulated transcriptome for primary progenitors, including Tnfr-sf13c as a novel mediator of EPO- dependent erythroblast formationDiminished hematopoietic activity associated with alterations in innate and adaptive immunity in a mouse model of human monocytic ehrlichiosis.Blood disorders typically associated with renal transplantationGene profiling of the erythro- and megakaryoblastic leukaemias induced by the Graffi murine retrovirus.Effects of the NUP98-DDX10 oncogene on primary human CD34+ cells: role of a conserved helicase motifGenetic inactivation of the pancreatitis-inducible gene Nupr1 impairs PanIN formation by modulating Kras(G12D)-induced senescenceStat5 regulates cellular iron uptake of erythroid cells via IRP-2 and TfR-1.Down-regulation of Myc is essential for terminal erythroid maturationDuring EPO or anemia challenge, erythroid progenitor cells transit through a selectively expandable proerythroblast poolConstitutive phosphorylation of GATA-1 at serine²⁶ attenuates the colony-forming activity of erythrocyte-committed progenitors.β-thalassemia: a model for elucidating the dynamic regulation of ineffective erythropoiesis and iron metabolism.Transcriptome Reveals 1400-Fold Upregulation of APOA4-APOC3 and 1100-Fold Downregulation of GIF in the Patients with Polycythemia-Induced Gastric Injury.Spry1 as a novel regulator of erythropoiesis, EPO/EPOR target, and suppressor of JAK2.Erythropoietin-induced changes in brain gene expression reveal induction of synaptic plasticity genes in experimental stroke.Elevated cyclin G2 expression intersects with DNA damage checkpoint signaling and is required for a potent G2/M checkpoint arrest response to doxorubicin.Pivotal Role of the Chromatin Protein Nupr1 in Kras-Induced Senescence and Transformation.Erythropoietin-directed erythropoiesis depends on serpin inhibition of erythroblast lysosomal cathepsins.EPO receptor circuits for primary erythroblast survivalDecreased differentiation of erythroid cells exacerbates ineffective erythropoiesis in beta-thalassemiaAttenuation of EPO-dependent erythroblast formation by death-associated protein kinase-2.CNTO 530 functions as a potent EPO mimetic via unique sustained effects on bone marrow proerythroblast pools.A KIT juxtamembrane PY567 -directed pathway provides nonredundant signals for erythroid progenitor cell development and stress erythropoiesis.Radioprotective effects of oral 17-dimethylaminoethylamino-17-demethoxygeldanamycin in mice: bone marrow and small intestine.Protein abundance of AKT and ERK pathway components governs cell type-specific regulation of proliferation.Erythropoietin receptor response circuitsAnemia, ineffective erythropoiesis, and hepcidin: interacting factors in abnormal iron metabolism leading to iron overload in β-thalassemia.Targeting EPO and EPO receptor pathways in anemia and dysregulated erythropoiesis.New strategies to target iron metabolism for the treatment of beta thalassemiaDYRK3 dual-specificity kinase attenuates erythropoiesis during anemiabeta-Thalassemia: HiJAKing Ineffective Erythropoiesis and Iron OverloadMitochondrial DNA 10609T promotes hypoxia-induced increase of intracellular ROS and is a risk factor of high altitude polycythemia.Cyclin G2 promotes cell cycle arrest in breast cancer cells responding to fulvestrant and metformin and correlates with patient survival.Stat5 activation enables erythropoiesis in the absence of EpoR and Jak2.Mechanism of apoptosis involved in gastric mucosal lesions in Tibetans with high-altitude polycythemia.What can we learn from ineffective erythropoiesis in thalassemia?Inhibition of heme oxygenase ameliorates anemia and reduces iron overload in a β-thalassemia mouse model.
P2860
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P2860
EPO modulation of cell-cycle regulatory genes, and cell division, in primary bone marrow erythroblasts
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
EPO modulation of cell-cycle r ...... mary bone marrow erythroblasts
@ast
EPO modulation of cell-cycle r ...... mary bone marrow erythroblasts
@en
type
label
EPO modulation of cell-cycle r ...... mary bone marrow erythroblasts
@ast
EPO modulation of cell-cycle r ...... mary bone marrow erythroblasts
@en
prefLabel
EPO modulation of cell-cycle r ...... mary bone marrow erythroblasts
@ast
EPO modulation of cell-cycle r ...... mary bone marrow erythroblasts
@en
P2093
P2860
P1433
P1476
EPO modulation of cell-cycle r ...... mary bone marrow erythroblasts
@en
P2093
Don M Wojchowski
Estelle Houde
Madhu Menon
Oleg Bogachev
Olga Bogacheva
Pradeep Sathyanarayana
Sarah Browne
William Kapelle
P2860
P304
P356
10.1182/BLOOD-2006-12-063503
P407
P577
2007-06-04T00:00:00Z