PABPN1-Dependent mRNA Processing Induces Muscle Wasting.
about
PABPN1 gene therapy for oculopharyngeal muscular dystrophyCytokine genes as potential biomarkers for muscle weakness in OPMD.Dysfunctional transcripts are formed by alternative polyadenylation in OPMD.Proteasomal activity-based probes mark protein homeostasis in muscles.Nuclear poly(A) binding protein 1 (PABPN1) and Matrin3 interact in muscle cells and regulate RNA processing.Novel mouse models of oculopharyngeal muscular dystrophy (OPMD) reveal early onset mitochondrial defects and suggest loss of PABPN1 may contribute to pathology.
P2860
PABPN1-Dependent mRNA Processing Induces Muscle Wasting.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
PABPN1-Dependent mRNA Processing Induces Muscle Wasting.
@ast
PABPN1-Dependent mRNA Processing Induces Muscle Wasting.
@en
type
label
PABPN1-Dependent mRNA Processing Induces Muscle Wasting.
@ast
PABPN1-Dependent mRNA Processing Induces Muscle Wasting.
@en
prefLabel
PABPN1-Dependent mRNA Processing Induces Muscle Wasting.
@ast
PABPN1-Dependent mRNA Processing Induces Muscle Wasting.
@en
P2093
P2860
P50
P1433
P1476
PABPN1-Dependent mRNA Processing Induces Muscle Wasting
@en
P2093
Maaike van Putten
Yvonne D Krom
P2860
P304
P356
10.1371/JOURNAL.PGEN.1006031
P577
2016-05-06T00:00:00Z