Interferon alpha and Tat involvement in the immunosuppression of uninfected T cells and C-C chemokine decline in AIDS.
about
Amplification of the inflammatory cellular redox state by human immunodeficiency virus type 1-immunosuppressive tat and gp160 proteinsPerforin-low memory CD8+ cells are the predominant T cells in normal humans that synthesize the beta -chemokine macrophage inflammatory protein-1betaPivotal role of cyclic nucleoside phosphodiesterase 4 in Tat-mediated CD4+ T cell hyperactivation and HIV type 1 replicationProliferative activity of extracellular HIV-1 Tat protein in human epithelial cells: expression profile of pathogenetically relevant genesDifferences in time of virus appearance in the blood and virus-specific immune responses in intravenous and intrarectal primary SIVmac251 infection of rhesus macaques; a pilot studyTat acetyl-acceptor lysines are important for human immunodeficiency virus type-1 replicationMultiple effects of HIV-1 trans-activator protein on the pathogenesis of HIV-1 infectionPlasmacytoid dendritic cells accumulate and secrete interferon alpha in lymph nodes of HIV-1 patients.HIV-1 Tat second exon limits the extent of Tat-mediated modulation of interferon-stimulated genes in antigen presenting cells.Respiratory syncytial virus interferon antagonist NS1 protein suppresses and skews the human T lymphocyte responseInduction of neutralizing antibodies and Th1-polarized and CD4-independent CD8+ T-cell responses following delivery of human immunodeficiency virus type 1 Tat protein by recombinant adenylate cyclase of Bordetella pertussis.Interferon-α abrogates tolerance induction by human tolerogenic dendritic cellsRegulation of TNF-related apoptosis-inducing ligand on primary CD4+ T cells by HIV-1: role of type I IFN-producing plasmacytoid dendritic cells.A Tat subunit vaccine confers protective immunity against the immune-modulating activity of the human immunodeficiency virus type-1 Tat protein in mice.Using death to one's advantage: HIV modulation of apoptosis.Differential expression of IFN-alpha and TRAIL/DR5 in lymphoid tissue of progressor versus nonprogressor HIV-1-infected patients.Tat-neutralizing antibodies in vaccinated macaques.Interleukin-7-dependent production of RANTES that correlates with human immunodeficiency virus disease progression.Human retroviruses after 20 years: a perspective from the past and prospects for their future control.Monocytes treated with human immunodeficiency virus Tat kill uninfected CD4(+) cells by a tumor necrosis factor-related apoptosis-induced ligand-mediated mechanism.The HIV-1 Tat protein induces the activation of CD8+ T cells and affects in vivo the magnitude and kinetics of antiviral responses.Vaccination with tat toxoid attenuates disease in simian/HIV-challenged macaques.Transcriptional profiles of latent human immunodeficiency virus in infected individuals: effects of Tat on the host and reservoir.IL-7 receptor recovery on CD8 T-cells isolated from HIV+ patients is inhibited by the HIV Tat proteinHigher macrophage inflammatory protein (MIP)-1alpha and MIP-1beta levels from CD8+ T cells are associated with asymptomatic HIV-1 infectionDistinct transcriptional profiles in ex vivo CD4+ and CD8+ T cells are established early in human immunodeficiency virus type 1 infection and are characterized by a chronic interferon response as well as extensive transcriptional changes in CD8+ T cCD4+ T-cell death induced by infectious and noninfectious HIV-1: role of type 1 interferon-dependent, TRAIL/DR5-mediated apoptosisDendritic cells infected with vpr-positive human immunodeficiency virus type 1 induce CD8+ T-cell apoptosis via upregulation of tumor necrosis factor alpha.Tat as one key to HIV-induced immune pathogenesis and Tat (correction of Pat) toxoid as an important component of a vaccineHIV turns plasmacytoid dendritic cells (pDC) into TRAIL-expressing killer pDC and down-regulates HIV coreceptors by Toll-like receptor 7-induced IFN-alphaSjTat-TPI facilitates adaptive T-cell responses and reduces hepatic pathology during Schistosoma japonicum infection in BALB/c miceChronic CD4+ T-cell activation and depletion in human immunodeficiency virus type 1 infection: type I interferon-mediated disruption of T-cell dynamics.HIV-1 immunopathogenesis: how good interferon turns bad.Type I interferon-dependent gene MxA in perinatal HIV-infected patients under antiretroviral therapy as marker for therapy failure and blood plasmacytoid dendritic cells depletionHost CCL3L1 gene copy number in relation to HIV-1-specific CD4+ and CD8+ T-cell responses and viral load in South African women.Generation and characterization of neutralizing human monoclonal antibodies against human immunodeficiency virus type 1 Tat antigenTat-induced FOXO3a is a key mediator of apoptosis in HIV-1-infected human CD4+ T lymphocytes.HIV-1 Tat mimetic of VEGF correlates with increased microvessels density in AIDS-related diffuse large B-cell and Burkitt lymphomas.Mendelian randomization: potential use of genetics to enable causal inferences regarding HIV-associated biomarkers and outcomes.Contribution of nonneutralizing vaccine-elicited antibody activities to improved protective efficacy in rhesus macaques immunized with Tat/Env compared with multigenic vaccines.
P2860
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P2860
Interferon alpha and Tat involvement in the immunosuppression of uninfected T cells and C-C chemokine decline in AIDS.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
Interferon alpha and Tat invol ...... C-C chemokine decline in AIDS.
@ast
Interferon alpha and Tat invol ...... C-C chemokine decline in AIDS.
@en
type
label
Interferon alpha and Tat invol ...... C-C chemokine decline in AIDS.
@ast
Interferon alpha and Tat invol ...... C-C chemokine decline in AIDS.
@en
prefLabel
Interferon alpha and Tat invol ...... C-C chemokine decline in AIDS.
@ast
Interferon alpha and Tat invol ...... C-C chemokine decline in AIDS.
@en
P2093
P2860
P356
P1476
Interferon alpha and Tat invol ...... C-C chemokine decline in AIDS.
@en
P2093
A Gringeri
E Santagostino
J F Zagury
J Rappaport
P2860
P304
P356
10.1073/PNAS.95.7.3851
P407
P50
P577
1998-03-01T00:00:00Z