Human Langerhans cells use an IL-15R-α/IL-15/pSTAT5-dependent mechanism to break T-cell tolerance against the self-differentiation tumor antigen WT1. - Wikidata - wikimedia - TriplyDB

Human Langerhans cells use an IL-15R-α/IL-15/pSTAT5-dependent mechanism to break T-cell tolerance against the self-differentiation tumor antigen WT1.

Human Langerhans cells use an IL-15R-α/IL-15/pSTAT5-dependent mechanism to break T-cell tolerance against the self-differentiation tumor antigen WT1.

http://www.wikidata.org/entity/Q36014997

about

Functional Specialization of Skin Dendritic Cell Subsets in Regulating T Cell Responses Reprogramming tumor-infiltrating dendritic cells for CD103+ CD8+ mucosal T-cell differentiation and breast cancer rejection.Phenotypic and functional activation of hyporesponsive KIRnegNKG2Aneg human NK-cell precursors requires IL12p70 provided by Poly(I:C)-matured monocyte-derived dendritic cells.Dendritic-cell-based therapeutic cancer vaccines Exploitation of Langerhans cells for in vivo DNA vaccine delivery into the lymph nodes.TLR-9 and IL-15 Synergy Promotes the In Vitro Clonal Expansion of Chronic Lymphocytic Leukemia B Cells.T-cell Exhaustion in Multiple Myeloma Relapse after Autotransplant: Optimal Timing of Immunotherapy New insights into the phenotype of human dendritic cell populations.Langerhans-type and monocyte-derived human dendritic cells have different susceptibilities to mRNA electroporation with distinct effects on maturation and activation: implications for immunogenicity in dendritic cell-based immunotherapy.Human Dendritic Cells Mitigate NK-Cell Dysfunction Mediated by Nonselective JAK1/2 Blockade.A review of dendritic cell therapy for cancer: progress and challenges.Human dendritic cells subsets as targets and vectors for therapy.Human dendritic cell subsets in vaccination.Interleukin-15 dendritic cells as vaccine candidates for cancer immunotherapy.Dendritic cell vaccine against leukemia: advances and perspectives.Dendritic cell-targeted vaccines.Duality at the gate: Skin dendritic cells as mediators of vaccine immunity and tolerance Soluble and membrane-bound interleukin (IL)-15 Rα/IL-15 complexes mediate proliferation of high-avidity central memory CD8+ T cells for adoptive immunotherapy of cancer and infections.Dendritic Cell Therapies for Hematologic Malignancies.Targeting C-type lectin receptors: a high-carbohydrate diet for dendritic cells to improve cancer vaccines Human CD1c+ dendritic cells drive the differentiation of CD103+ CD8+ mucosal effector T cells via the cytokine TGF-β.Langerhans cells and NK cells cooperate in the inhibition of chemical skin carcinogenesis.Comparative genomics analysis of mononuclear phagocyte subsets confirms homology between lymphoid tissue-resident and dermal XCR1(+) DCs in mouse and human and distinguishes them from Langerhans cells Cell-to-cell variability analysis dissects the plasticity of signaling of common γ chain cytokines in T cells.Timing Is Everything: Combining Post-Transplantation Adoptive Cell Therapy and Tumor Vaccines.Human dendritic cell subsets: an update.Langerhans-type dendritic cells electroporated with TRP-2 mRNA stimulate cellular immunity against melanoma: Results of a phase I vaccine trial.

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P2860

Human Langerhans cells use an IL-15R-α/IL-15/pSTAT5-dependent mechanism to break T-cell tolerance against the self-differentiation tumor antigen WT1.

http://www.wikidata.org/entity/Q36014997

description

2012 nî lūn-bûn

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2012年の論文

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年學術文章

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2012年學術文章

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2012年學術文章

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name

Human Langerhans cells use an ...... erentiation tumor antigen WT1.

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Human Langerhans cells use an ...... erentiation tumor antigen WT1.

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Human Langerhans cells use an ...... ferentiation tumor antigen WT1

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Babak Mehrara

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Brian C Betts

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Christian Münz

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David J Chung

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Emanuela Romano

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Erin T St Angelo

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Francesca Avogadri

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Glenn Heller

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James W Young

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Jesse W Cotari

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P2860

Janus kinases in immune cell signaling

Impact of cryopreservation on tetramer, cytokine flow cytometry, and ELISPOT

Successful adoptive transfer and in vivo expansion of human haploidentical NK cells in patients with cancer

Induction of complete and molecular remissions in acute myeloid leukemia by Wilms' tumor 1 antigen-targeted dendritic cell vaccination

Designing vaccines based on biology of human dendritic cell subsets

Origin, homeostasis and function of Langerhans cells and other langerin-expressing dendritic cells.

Improved outcome in HLA-identical sibling hematopoietic stem-cell transplantation for acute myelogenous leukemia predicted by KIR and HLA genotypes.

NK cell survival mediated through the regulatory synapse with human DCs requires IL-15Ralpha.

Human dendritic cells: potent antigen-presenting cells at the crossroads of innate and adaptive immunity.

Identification of a radio-resistant and cycling dermal dendritic cell population in mice and men.

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5182-5190

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10.1182/BLOOD-2011-09-382200

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P433

22

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119

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Grégoire Altan-Bonnet

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2012-04-17T00:00:00Z

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224284214

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22510877

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3369609

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