NK cell survival mediated through the regulatory synapse with human DCs requires IL-15Ralpha.
about
Identification of a polyI:C-inducible membrane protein that participates in dendritic cell-mediated natural killer cell activationCytokines as Adjuvants for Vaccine and Cellular Therapies for Cancer.IL-15.IL-15Rα complex shedding following trans-presentation is essential for the survival of IL-15 responding NK and T cellsDendritic cells during Epstein Barr virus infection.Differential mechanisms of memory CD8 T cell maintenance by individual myeloid cell types.Memory-like responses of natural killer cells.KIR and HLA-C interactions promote differential dendritic cell maturation and is a major determinant of graft failure following kidney transplantation.In vivo role of Flt3 ligand and dendritic cells in NK cell homeostasisPhenotypic and functional activation of hyporesponsive KIRnegNKG2Aneg human NK-cell precursors requires IL12p70 provided by Poly(I:C)-matured monocyte-derived dendritic cells.Dysfunction of dendritic cells in aged C57BL/6 mice leads to failure of natural killer cell activation and of tumor eradication.Infection-induced regulation of natural killer cells by macrophages and collagen at the lymph node subcapsular sinus.Human NK cells of mice with reconstituted human immune system components require preactivation to acquire functional competence.Antibodies to MOG have a demyelination phenotype and affect oligodendrocyte cytoskeleton.Expression of IL-15RA or an IL-15/IL-15RA fusion on CD8+ T cells modifies adoptively transferred T-cell function in cisImpaired IFN-γ production and proliferation of NK cells in multiple sclerosis.Interactions of human myeloid cells with natural killer cell subsets in vitro and in vivoNK cell activation in human hantavirus infection explained by virus-induced IL-15/IL15Rα expression.Cytoskeletal stabilization of inhibitory interactions in immunologic synapses of mature human dendritic cells with natural killer cells.Virally infected and matured human dendritic cells activate natural killer cells via cooperative activity of plasma membrane-bound TNF and IL-15.Kruppel-like factor 4 (KLF4) promotes the survival of natural killer cells and maintains the number of conventional dendritic cells in the spleenHuman Langerhans cells use an IL-15R-α/IL-15/pSTAT5-dependent mechanism to break T-cell tolerance against the self-differentiation tumor antigen WT1.NK Cell Proliferation Induced by IL-15 Transpresentation Is Negatively Regulated by Inhibitory Receptors.IL-15Ralpha chaperones IL-15 to stable dendritic cell membrane complexes that activate NK cells via trans presentation.Noncytotoxic functions of NK cells: direct pathogen restriction and assistance to adaptive immunity.Dendritic cell and natural killer cell cross-talk: a pivotal role of CX3CL1 in NK cytoskeleton organization and activationNatural killer cells in immunodefense against infective agents.Signalling, inflammation and arthritis: Crossed signals: the role of interleukin-15 and -18 in autoimmunity.The killer's kiss: the many functions of NK cell immunological synapses.Prolonged contact with dendritic cells turns lymph node-resident NK cells into anti-tumor effectors.Regulatory NK-cell functions in inflammation and autoimmunity.Dendritic cell derived cytokines in human natural killer cell differentiation and activation.Neural stem cells sustain natural killer cells that dictate recovery from brain inflammation.Tumor immune therapy: lessons from infection and implications for cancer - can IL-7 help overcome immune inhibitory networks?The bidirectional crosstalk between human dendritic cells and natural killer cells.Natural killer cell activation by dendritic cells: balancing inhibitory and activating signals.Mechanisms of NK cell activation: CD4(+) T cells enter the scene.Use of allogeneic NK cells for cancer immunotherapy.Dynamics of NK cell interactions in vivo.Tissue-specific effector functions of innate lymphoid cells.NK cells after transplantation: friend or foe.
P2860
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P2860
NK cell survival mediated through the regulatory synapse with human DCs requires IL-15Ralpha.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
NK cell survival mediated thro ...... uman DCs requires IL-15Ralpha.
@ast
NK cell survival mediated thro ...... uman DCs requires IL-15Ralpha.
@en
type
label
NK cell survival mediated thro ...... uman DCs requires IL-15Ralpha.
@ast
NK cell survival mediated thro ...... uman DCs requires IL-15Ralpha.
@en
prefLabel
NK cell survival mediated thro ...... uman DCs requires IL-15Ralpha.
@ast
NK cell survival mediated thro ...... uman DCs requires IL-15Ralpha.
@en
P2093
P2860
P356
P1476
NK cell survival mediated thro ...... uman DCs requires IL-15Ralpha.
@en
P2093
Christian Münz
Fabienne Brilot
Frida Arrey
Susanne M Roberts
Till Strowig
P2860
P304
P356
10.1172/JCI31751
P407
P577
2007-11-01T00:00:00Z