Deletion of GαZ protein protects against diet-induced glucose intolerance via expansion of β-cell mass
about
Pancreatic β-cell proliferation in obesity.Regulation of pancreatic β-cell function and mass dynamics by prostaglandin signaling.Opposing effects of prostaglandin E2 receptors EP3 and EP4 on mouse and human β-cell survival and proliferationInhibitory G proteins and their receptors: emerging therapeutic targets for obesity and diabetes.The gastrin-releasing peptide analog bombesin preserves exocrine and endocrine pancreas morphology and function during parenteral nutrition.Synergy Between Gαz Deficiency and GLP-1 Analog Treatment in Preserving Functional β-Cell Mass in Experimental Diabetes.Prostaglandin E2 receptor, EP3, is induced in diabetic islets and negatively regulates glucose- and hormone-stimulated insulin secretion.The EP3 Receptor: Exploring a New Target for Type 2 Diabetes Therapeutics.A method for mouse pancreatic islet isolation and intracellular cAMP determinationGnaz couples the circadian and dopaminergic system to G protein-mediated signaling in mouse photoreceptors.Role of G-proteins in islet function in health and diabetes.The Inhibitory G Protein α-Subunit, Gαz, Promotes Type 1 Diabetes-Like Pathophysiology in NOD Mice.Targeting dysfunctional beta-cell signaling for the potential treatment of type 1 diabetes mellitus.
P2860
Q33578671-85778B43-9936-46BB-92A4-09B110D312AEQ33714751-336D2CA0-CED3-47A1-AA95-B7A1D1B2FB96Q33726561-00B826FE-2382-4426-ADAD-C3889008BCACQ33844872-287AC8A0-93E0-48FF-9E63-669483CCCF25Q36066441-AB38F17B-A157-479E-82A1-C08443CC2FBFQ36859559-62BAF048-7EA9-4EF8-AB73-D0E60EC45C49Q36867528-2FE2850F-B1BF-45D7-B8AD-9E68B15FB14CQ40591318-A415414E-75A6-4279-8794-F361D0704E65Q42101100-3EC1B4B9-2EA7-4F18-8879-33162051F333Q43291503-25EEEDA1-C0A0-4DF4-9C8C-64334A24BBACQ47843056-0CD11086-191A-4534-8754-EC8BE6590E6EQ47913426-518EC210-4F2D-4614-8709-9648B4D642AAQ52674501-2D670674-3F9C-44E6-BDFD-E19E9F1B430F
P2860
Deletion of GαZ protein protects against diet-induced glucose intolerance via expansion of β-cell mass
description
2012 nî lūn-bûn
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2012年の論文
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2012年学术文章
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2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
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2012年學術文章
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2012年學術文章
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name
Deletion of GαZ protein protec ...... e via expansion of β-cell mass
@ast
Deletion of GαZ protein protec ...... e via expansion of β-cell mass
@en
type
label
Deletion of GαZ protein protec ...... e via expansion of β-cell mass
@ast
Deletion of GαZ protein protec ...... e via expansion of β-cell mass
@en
prefLabel
Deletion of GαZ protein protec ...... e via expansion of β-cell mass
@ast
Deletion of GαZ protein protec ...... e via expansion of β-cell mass
@en
P2093
P2860
P356
P1476
Deletion of GαZ protein protec ...... e via expansion of β-cell mass
@en
P2093
Christopher B Newgard
Harpreet K Brar
Jennifer B Moss
Michelle E Kimple
Nathan A Truchan
Patrick J Casey
Renee L Pasker
Taylor C Rosa
P2860
P304
20344-20355
P356
10.1074/JBC.M112.359745
P407
P577
2012-03-28T00:00:00Z