Prostaglandin E2 receptor, EP3, is induced in diabetic islets and negatively regulates glucose- and hormone-stimulated insulin secretion. - Wikidata - wikimedia - TriplyDB

Prostaglandin E2 receptor, EP3, is induced in diabetic islets and negatively regulates glucose- and hormone-stimulated insulin secretion.

Prostaglandin E2 receptor, EP3, is induced in diabetic islets and negatively regulates glucose- and hormone-stimulated insulin secretion.

http://www.wikidata.org/entity/Q36867528

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Lipotoxicity in the pancreatic beta cell: not just survival and function, but proliferation as well?Regulation of pancreatic β-cell function and mass dynamics by prostaglandin signaling.Opposing effects of prostaglandin E2 receptors EP3 and EP4 on mouse and human β-cell survival and proliferation Inhibitory G proteins and their receptors: emerging therapeutic targets for obesity and diabetes.Group X secretory phospholipase A2 regulates insulin secretion through a cyclooxygenase-2-dependent mechanism.Targets and candidate agents for type 2 diabetes treatment with computational bioinformatics approach.Minireview: 12-Lipoxygenase and Islet β-Cell Dysfunction in Diabetes.Alternative rapamycin treatment regimens mitigate the impact of rapamycin on glucose homeostasis and the immune system.Glucagon-Like Peptide-1 Regulates Cholecystokinin Production in β-Cells to Protect From Apoptosis Myeloid Cell Prostaglandin E2 Receptor EP4 Modulates Cytokine Production but Not Atherogenesis in a Mouse Model of Type 1 Diabetes.Cytosolic and Calcium-Independent Phospholipases A2 Activation and Prostaglandins E2 Are Associated with Escherichia coli-Induced Reduction of Insulin Secretion in INS-1E Cells.The PGE2 EP3 Receptor Regulates Diet-Induced Adiposity in Male Mice A single-islet microplate assay to measure mouse and human islet insulin secretion PGE2, Kidney Disease, and Cardiovascular Risk: Beyond Hypertension and Diabetes.Inhibition of the MAP3 kinase Tpl2 protects rodent and human β-cells from apoptosis and dysfunction induced by cytokines and enhances anti-inflammatory actions of exendin-4.Synergy Between Gαz Deficiency and GLP-1 Analog Treatment in Preserving Functional β-Cell Mass in Experimental Diabetes.A Single-Cell Transcriptome Atlas of the Human Pancreas.Prostaglandin E2 receptor EP3 regulates both adipogenesis and lipolysis in mouse white adipose tissue.Enriching Islet Phospholipids With Eicosapentaenoic Acid Reduces Prostaglandin E2 Signaling and Enhances Diabetic β-Cell Function.Role of cytosolic and calcium independent phospholipases A(2) in insulin secretion impairment of INS-1E cells infected by S. aureus.Leukotriene D4 and prostaglandin E2 signals synergize and potentiate vascular inflammation in a mast cell-dependent manner through cysteinyl leukotriene receptor 1 and E-prostanoid receptor 3.The EP3 Receptor: Exploring a New Target for Type 2 Diabetes Therapeutics.Prostaglandin EP3 Receptor Antagonists May Provide Novel Treatment for Diabetes.Mir-204 Controls Glucagon-Like Peptide 1 Receptor Expression and Agonist Function.The Inhibitory G Protein α-Subunit, Gαz, Promotes Type 1 Diabetes-Like Pathophysiology in NOD Mice.The dual role of group V secretory phospholipase A2 in pancreatic β-cells.Anti-inflammatory effects of linagliptin in hemodialysis patients with diabetes.Dietary polyunsaturated fatty acids and their metabolites: Implications for diabetes pathophysiology, prevention, and treatment.

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P2860

Prostaglandin E2 receptor, EP3, is induced in diabetic islets and negatively regulates glucose- and hormone-stimulated insulin secretion.

http://www.wikidata.org/entity/Q36867528

description

2013 nî lūn-bûn

@nan

2013年の論文

@ja

2013年論文

@yue

2013年論文

@zh-hant

2013年論文

@zh-hk

2013年論文

@zh-mo

2013年論文

@zh-tw

2013年论文

@wuu

2013年论文

@zh

2013年论文

@zh-cn

name

Prostaglandin E2 receptor, EP3 ...... -stimulated insulin secretion.

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type

label

Prostaglandin E2 receptor, EP3 ...... -stimulated insulin secretion.

@en

prefLabel

Prostaglandin E2 receptor, EP3 ...... -stimulated insulin secretion.

@en

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Prostaglandin E2 receptor, EP3 ...... -stimulated insulin secretion.

@en

P2093

Alan D Attie

http://www.w3.org/2001/XMLSchema#string

Harpreet K Brar

http://www.w3.org/2001/XMLSchema#string

Joshua C Neuman

http://www.w3.org/2001/XMLSchema#string

Mark P Keller

http://www.w3.org/2001/XMLSchema#string

Mary R Rabaglia

http://www.w3.org/2001/XMLSchema#string

Michelle E Kimple

http://www.w3.org/2001/XMLSchema#string

Nathan A Truchan

http://www.w3.org/2001/XMLSchema#string

Renee L Pasker

http://www.w3.org/2001/XMLSchema#string

P2860

Mechanisms of action of glucagon-like peptide 1 in the pancreas

Mechanisms of inhibition of insulin release.

Ligand binding specificities of the eight types and subtypes of the mouse prostanoid receptors expressed in Chinese hamster ovary cells

Positional cloning of a type 2 diabetes quantitative trait locus; tomosyn-2, a negative regulator of insulin secretion

Mouse prostaglandin E receptor EP3 subtype mediates calcium signals via Gi in cDNA-transfected Chinese hamster ovary cells

Cloning and expression of a cDNA for mouse prostaglandin E receptor EP3 subtype.

FoxM1 is up-regulated by obesity and stimulates beta-cell proliferation.

Isoforms of the EP3 subtype of human prostaglandin E2 receptor transduce both intracellular calcium and cAMP signals.

Night eating and obesity in the EP3R-deficient mouse.

Deletion of GαZ protein protects against diet-induced glucose intolerance via expansion of β-cell mass

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1904-1912

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scholarly article

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10.2337/DB12-0769

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6

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62

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2013-01-24T00:00:00Z

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235371847

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23349487

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3661627

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