Prostaglandin E2 receptor, EP3, is induced in diabetic islets and negatively regulates glucose- and hormone-stimulated insulin secretion.
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Lipotoxicity in the pancreatic beta cell: not just survival and function, but proliferation as well?Regulation of pancreatic β-cell function and mass dynamics by prostaglandin signaling.Opposing effects of prostaglandin E2 receptors EP3 and EP4 on mouse and human β-cell survival and proliferationInhibitory G proteins and their receptors: emerging therapeutic targets for obesity and diabetes.Group X secretory phospholipase A2 regulates insulin secretion through a cyclooxygenase-2-dependent mechanism.Targets and candidate agents for type 2 diabetes treatment with computational bioinformatics approach.Minireview: 12-Lipoxygenase and Islet β-Cell Dysfunction in Diabetes.Alternative rapamycin treatment regimens mitigate the impact of rapamycin on glucose homeostasis and the immune system.Glucagon-Like Peptide-1 Regulates Cholecystokinin Production in β-Cells to Protect From ApoptosisMyeloid Cell Prostaglandin E2 Receptor EP4 Modulates Cytokine Production but Not Atherogenesis in a Mouse Model of Type 1 Diabetes.Cytosolic and Calcium-Independent Phospholipases A2 Activation and Prostaglandins E2 Are Associated with Escherichia coli-Induced Reduction of Insulin Secretion in INS-1E Cells.The PGE2 EP3 Receptor Regulates Diet-Induced Adiposity in Male MiceA single-islet microplate assay to measure mouse and human islet insulin secretionPGE2, Kidney Disease, and Cardiovascular Risk: Beyond Hypertension and Diabetes.Inhibition of the MAP3 kinase Tpl2 protects rodent and human β-cells from apoptosis and dysfunction induced by cytokines and enhances anti-inflammatory actions of exendin-4.Synergy Between Gαz Deficiency and GLP-1 Analog Treatment in Preserving Functional β-Cell Mass in Experimental Diabetes.A Single-Cell Transcriptome Atlas of the Human Pancreas.Prostaglandin E2 receptor EP3 regulates both adipogenesis and lipolysis in mouse white adipose tissue.Enriching Islet Phospholipids With Eicosapentaenoic Acid Reduces Prostaglandin E2 Signaling and Enhances Diabetic β-Cell Function.Role of cytosolic and calcium independent phospholipases A(2) in insulin secretion impairment of INS-1E cells infected by S. aureus.Leukotriene D4 and prostaglandin E2 signals synergize and potentiate vascular inflammation in a mast cell-dependent manner through cysteinyl leukotriene receptor 1 and E-prostanoid receptor 3.The EP3 Receptor: Exploring a New Target for Type 2 Diabetes Therapeutics.Prostaglandin EP3 Receptor Antagonists May Provide Novel Treatment for Diabetes.Mir-204 Controls Glucagon-Like Peptide 1 Receptor Expression and Agonist Function.The Inhibitory G Protein α-Subunit, Gαz, Promotes Type 1 Diabetes-Like Pathophysiology in NOD Mice.The dual role of group V secretory phospholipase A2 in pancreatic β-cells.Anti-inflammatory effects of linagliptin in hemodialysis patients with diabetes.Dietary polyunsaturated fatty acids and their metabolites: Implications for diabetes pathophysiology, prevention, and treatment.
P2860
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P2860
Prostaglandin E2 receptor, EP3, is induced in diabetic islets and negatively regulates glucose- and hormone-stimulated insulin secretion.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Prostaglandin E2 receptor, EP3 ...... -stimulated insulin secretion.
@en
type
label
Prostaglandin E2 receptor, EP3 ...... -stimulated insulin secretion.
@en
prefLabel
Prostaglandin E2 receptor, EP3 ...... -stimulated insulin secretion.
@en
P2093
P2860
P356
P1433
P1476
Prostaglandin E2 receptor, EP3 ...... -stimulated insulin secretion.
@en
P2093
Alan D Attie
Harpreet K Brar
Joshua C Neuman
Mark P Keller
Mary R Rabaglia
Michelle E Kimple
Nathan A Truchan
Renee L Pasker
P2860
P304
P356
10.2337/DB12-0769
P407
P577
2013-01-24T00:00:00Z