A role for the IkappaB family member Bcl-3 in the control of central immunologic tolerance
about
Atypical IκB proteins - nuclear modulators of NF-κB signalingRegulation of the Adaptive Immune Response by the IκB Family Protein Bcl-3The tumor promoter and NF-κB modulator Bcl-3 regulates splenic B cell development.Roles of the NF-kappaB pathway in lymphocyte development and function.The repressing function of the oncoprotein BCL-3 requires CtBP, while its polyubiquitination and degradation involve the E3 ligase TBLR1.Direct and indirect roles of the LTbetaR pathway in central tolerance induction.The transcriptional specificity of NF-κB dimers is coded within the κB DNA response elementsThe NF-κB regulator Bcl-3 governs dendritic cell antigen presentation functions in adaptive immunityBcl3 prevents acute inflammatory lung injury in mice by restraining emergency granulopoiesis.The oncoprotein and transcriptional regulator Bcl-3 governs plasticity and pathogenicity of autoimmune T cellsEstablished thymic epithelial progenitor/stem cell-like cell lines differentiate into mature thymic epithelial cells and support T cell development.The IκB family member Bcl-3 coordinates the pulmonary defense against Klebsiella pneumoniae infection.The NF-κB regulator Bcl-3 modulates inflammation during contact hypersensitivity reactions in radioresistant cells.Roles of Bcl-3 in the pathogenesis of murine type 1 diabetesImpaired Bcl3 up-regulation leads to enhanced lipopolysaccharide-induced interleukin (IL)-23P19 gene expression in IL-10(-/-) mice.NIK promotes tissue destruction independently of the alternative NF-κB pathway through TNFR1/RIP1-induced apoptosis.The roles of the classical and alternative nuclear factor-kappaB pathways: potential implications for autoimmunity and rheumatoid arthritis.Differential NF-kappaB pathways induction by Lactobacillus plantarum in the duodenum of healthy humans correlating with immune tolerance.Transgenic Bcl-3 slows T cell proliferation.Thymic medullary epithelium and thymocyte self-tolerance require cooperation between CD28-CD80/86 and CD40-CD40L costimulatory pathways.Bcl-3 regulates TGFβ signaling by stabilizing Smad3 during breast cancer pulmonary metastasis.The complicated role of NF-kappaB in T-cell selection.It takes two to tango: IκBs, the multifunctional partners of NF-κB.NF-κB subunit specificity in hemopoiesis.TNF receptor family signaling in the development and functions of medullary thymic epithelial cells.Thymic stromal cell subsets for T cell development.Adaptive immune-mediated host resistance to Toxoplasma gondii is governed by the NF-κB regulator Bcl-3 in dendritic cells.Bcl-3 puts the brakes on contact hypersensitivity.
P2860
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P2860
A role for the IkappaB family member Bcl-3 in the control of central immunologic tolerance
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
A role for the IkappaB family ...... central immunologic tolerance
@ast
A role for the IkappaB family ...... central immunologic tolerance
@en
type
label
A role for the IkappaB family ...... central immunologic tolerance
@ast
A role for the IkappaB family ...... central immunologic tolerance
@en
prefLabel
A role for the IkappaB family ...... central immunologic tolerance
@ast
A role for the IkappaB family ...... central immunologic tolerance
@en
P2093
P2860
P1433
P1476
A role for the IkappaB family ...... central immunologic tolerance
@en
P2093
Estefania Claudio
Hongshan Wang
Keith Brown
Ulrich Siebenlist
P2860
P304
P356
10.1016/J.IMMUNI.2007.07.017
P407
P577
2007-09-01T00:00:00Z