about
Nitrile-containing pharmaceuticals: efficacious roles of the nitrile pharmacophoreThe ALTERNATE trial: assessing a biomarker driven strategy for the treatment of post-menopausal women with ER+/Her2- invasive breast cancerLetrozole increases ovarian growth and Cyp17a1 gene expression in the rat ovary.Predicting the reactivity of nitrile-carrying compounds with cysteine: a combined computational and experimental studyA randomized, double-blind, controlled study of exemestane versus anastrozole for the first-line treatment of postmenopausal Japanese women with hormone-receptor-positive advanced breast cancer.Role of aromatase in sex-specific cerebrovascular endothelial function in miceExemestane in the adjuvant treatment of breast cancer in postmenopausal women.An effect of letrozole on gastric cancer?Roscovitine confers tumor suppressive effect on therapy-resistant breast tumor cellsDevelopment and validation of a rapid LC-MS/MS method to quantify letrozole in human plasma and its application to therapeutic drug monitoring.Novel inhibitor discovery against aromatase through virtual screening and molecular dynamic simulation: a computational approach in drug designEffectiveness of aromatase inhibitors and tamoxifen in reducing subsequent breast cancer.Acute inhibition of neurosteroid estrogen synthesis suppresses status epilepticus in an animal model.Recent Progress in the Discovery of Next Generation Inhibitors of Aromatase from the Structure-Function Perspective.Stereological study of the effects of letrozole and estradiol valerate treatment on the ovary of rats.Inhibition of drug metabolizing cytochrome P450s by the aromatase inhibitor drug letrozole and its major oxidative metabolite 4,4'-methanol-bisbenzonitrile in vitro.Letrozole.Aromatase inhibition: a potential target for the management of recurrent or metastatic endometrial cancer by letrozole: more questions than answers?An overview of letrozole in postmenopausal women with hormone-responsive breast cancer.Molecular docking and 3D-QSAR-based virtual screening of flavonoids as potential aromatase inhibitors against estrogen-dependent breast cancer.Use of anastrozole in the chemoprevention and treatment of breast cancer: A literature review.Progesterone levels in letrozole associated controlled ovarian stimulation for fertility preservation in breast cancer patients.An ER activity profile including ER, PR, Bcl-2 and IGF-IR may have potential as selection criterion for letrozole or tamoxifen treatment of patients with advanced breast cancer.Variation in CYP2A6 Activity and Personalized Medicine.SPE-UPLC-MS/MS assay for determination of letrozole in human plasma and its application to bioequivalence study in healthy postmenopausal Indian women.Letrozole induces hepatotoxicity without causing oxidative stress: the protective effect of melatonin.
P2860
Q24569706-1600F9A4-91F6-4FA1-92B5-3A5CE2EBA972Q26786704-CA72D93F-EC3E-4EB6-9428-DAF22D23CBA9Q30414520-2BECDDB0-6ED3-41FC-AA62-9CFA5AB1ED75Q33636140-74DB039C-E09C-4B8B-AE63-AB15D0379269Q34347274-4BA8057D-CEAE-45A2-AF22-7CDF68FF79D2Q35089359-F6F610E6-5809-4297-B5EF-6C66220EAA02Q35440357-7B79FAE7-26D8-46A0-837A-8263FE9219D1Q35480777-D2DF0CA3-BEFE-4556-AEB5-BE22B92A82F1Q35558138-859612DC-5054-47B3-90BD-CB950CA2A9E7Q35758526-94D74BAA-EC1E-423D-B060-6BEBA56DE5D7Q35937856-D6395AE8-8AEF-4DB6-9053-BB0C4AA0B8DEQ36530770-0D3B4013-D6E5-4D0F-940B-DC852D3D3923Q36888650-9CD0F1F3-335D-4BA7-BB7F-2276DA8A36A4Q37025619-1E63EDE6-CFB2-4334-AAC6-7989EC8C37BFQ37264540-6ED875C9-72C1-4D53-A8C7-7838FDCC15D3Q37414581-1CFF986A-096C-4703-8781-564213D5A9A0Q37679903-F02471F7-4230-483A-A7FD-8B0A23372768Q37854068-0D19BD4A-F205-4422-A3BF-9E44E81AC90AQ37954137-1F03F99A-35A4-4655-8287-7B73CC1BCFB1Q38398595-9907D30B-E883-4D2B-A995-52DDE82A3B15Q39373643-C2EE06F2-4BAA-436B-AEC8-CBB5B9538725Q40799076-6D29A153-FEEA-4B57-88B8-590F553D4F62Q46144659-1D513F08-43BC-4DB5-A896-1B0791DC7678Q47163198-AEC6091B-CE82-498F-9D80-53D95562D956Q49657659-FB5FD987-7824-4C04-BE13-5CB103971425Q51561537-3980373E-7BF0-4338-8703-015BFE323BFA
P2860
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
The discovery and mechanism of action of letrozole.
@ast
The discovery and mechanism of action of letrozole.
@en
type
label
The discovery and mechanism of action of letrozole.
@ast
The discovery and mechanism of action of letrozole.
@en
prefLabel
The discovery and mechanism of action of letrozole.
@ast
The discovery and mechanism of action of letrozole.
@en
P2860
P921
P1476
The discovery and mechanism of action of letrozole.
@en
P2093
Ajay S Bhatnagar
P2860
P2888
P356
10.1007/S10549-007-9696-3
P407
P478
105 Suppl 1
P577
2007-10-03T00:00:00Z