{(1R,2R,4R)-4-methyl-1,2-cyclohexanediamine}oxalatoplatinum(II): a novel enantiomerically pure oxaliplatin derivative showing improved anticancer activity in vivo.
about
Anticancer activity of methyl-substituted oxaliplatin analogs.Oxidative DNA double strand breaks and autophagy in the antitumor effect of sterically hindered platinum(II) complexes in NSCLCsPlatinum-based drugs: past, present and future.Three-dimensional and co-culture models for preclinical evaluation of metal-based anticancer drugs.Response Profiling Using Shotgun Proteomics Enables Global Metallodrug Mechanisms of Action To Be Established.Theoretical investigations and density functional theory based quantitative structure-activity relationships model for novel cytotoxic platinum(IV) complexes.Ruthenium(II) arene PTA (RAPTA) complexes: impact of enantiomerically pure chiral ligands.Synthesis, in vitro cytotoxicity, and interaction with DNA of platinum(II) complexes with N-monocycloalkyl derivatives of 1R,2R-diaminocyclohexane as carrier ligands.Chiral platinum (II)-4-(2,3-dihydroxypropyl)- formamide oxo-aporphine (FOA) complexes promote tumor cells apoptosis by directly targeting G-quadruplex DNA in vitro and in vivo.Comparative studies of oxaliplatin-based platinum(iv) complexes in different in vitro and in vivo tumor models.Dinuclear Platinum(II) Complexes with Bone-Targeting Groups as Potential Anti-Osteosarcoma Agents.A fluorescent oxaliplatin derivative for investigation of oxaliplatin resistance using imaging techniques.Exploiting hydrogen bonding interactions to probe smaller linear and cyclic diamines binding to G-quadruplexes: a DFT and molecular dynamics study.Novel oxaliplatin derivatives with 1-(substituted benzyl)azetidine-3,3-dicarboxylate anions. Synthesis, cytotoxicity, and interaction with DNA.
P2860
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P2860
{(1R,2R,4R)-4-methyl-1,2-cyclohexanediamine}oxalatoplatinum(II): a novel enantiomerically pure oxaliplatin derivative showing improved anticancer activity in vivo.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
{(1R,2R,4R)-4-methyl-1,2-cyclo ...... d anticancer activity in vivo.
@ast
{(1R,2R,4R)-4-methyl-1,2-cyclo ...... d anticancer activity in vivo.
@en
type
label
{(1R,2R,4R)-4-methyl-1,2-cyclo ...... d anticancer activity in vivo.
@ast
{(1R,2R,4R)-4-methyl-1,2-cyclo ...... d anticancer activity in vivo.
@en
prefLabel
{(1R,2R,4R)-4-methyl-1,2-cyclo ...... d anticancer activity in vivo.
@ast
{(1R,2R,4R)-4-methyl-1,2-cyclo ...... d anticancer activity in vivo.
@en
P2093
P2860
P50
P356
P1476
{(1R,2R,4R)-4-methyl-1,2-cyclo ...... d anticancer activity in vivo.
@en
P2093
Claudia Dworak
Kristof Meelich
Ladislav Habala
Markus Galanski
Seied M Valiahdi
Sergey A Abramkin
P2860
P304
P356
10.1021/JM100953C
P407
P50
P577
2010-10-01T00:00:00Z