The MUC1-C oncoprotein binds to the BH3 domain of the pro-apoptotic BAX protein and blocks BAX function.

The MUC1-C oncoprotein binds to the BH3 domain of the pro-apoptotic BAX protein and blocks BAX function.

Item
http://www.wikidata.org/entity/Q36033113
Protein mislocalization: mechanisms, functions and clinical applications in cancer.Galectin-3 leads to attenuation of apoptosis through Bax heterodimerization in human thyroid carcinoma cellsMucin 1 gene silencing inhibits the growth of SMMC-7721 human hepatoma cells through Bax-mediated mitochondrial and caspase-8-mediated death receptor apoptotic pathwaysMolecular basis of antibody binding to mucin glycopeptides in lung cancerInhibition of the MUC1-C oncoprotein is synergistic with cytotoxic agents in the treatment of breast cancer cells.The combined treatment with novel platinum(II) complex and anti-MUC1 increases apoptotic response in MDA-MB-231 breast cancer cells.MUC1 upregulation promotes immune resistance in tumor cells undergoing brachyury-mediated epithelial-mesenchymal transition.MUC1-C Stabilizes MCL-1 in the Oxidative Stress Response of Triple-Negative Breast Cancer Cells to BCL-2 Inhibitors.Chemoresistance is associated with MUC1 and Lewis y antigen expression in ovarian epithelial cancers.MUC1 and metastatic cancer: expression, function and therapeutic targeting.Cellular and molecular biology of airway mucins.MUC1 in hematological malignancies.PPARγ E3 ubiquitin ligase regulates MUC1-C oncoprotein stability.Changes in pulmonary tissue structure and KL-6/MUC1 expression in a newborn rat model of hyperoxia-induced bronchopulmonary dysplasia.FGF1 induces resistance to chemotherapy in ovarian granulosa tumor cells through regulation of p53 mitochondrial localization.Peroxisome Proliferator-Activated Receptor γ and PGC-1α in Cancer: Dual Actions as Tumor Promoter and Suppressor.
P2860

The MUC1-C oncoprotein binds to the BH3 domain of the pro-apoptotic BAX protein and blocks BAX function.

Item
http://www.wikidata.org/entity/Q36033113
description
2012 nî lūn-bûn
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2012年の論文
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2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
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2012年论文
@zh-cn
name
The MUC1-C oncoprotein binds t ...... otein and blocks BAX function.
@ast
The MUC1-C oncoprotein binds t ...... otein and blocks BAX function.
@en
type
label
The MUC1-C oncoprotein binds t ...... otein and blocks BAX function.
@ast
The MUC1-C oncoprotein binds t ...... otein and blocks BAX function.
@en
prefLabel
The MUC1-C oncoprotein binds t ...... otein and blocks BAX function.
@ast
The MUC1-C oncoprotein binds t ...... otein and blocks BAX function.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P921
P932
P356
P1433
P1476
The MUC1-C oncoprotein binds t ...... otein and blocks BAX function.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P921
P932