Increased resting intracellular calcium modulates NF-κB-dependent inducible nitric-oxide synthase gene expression in dystrophic mdx skeletal myotubes
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Current understanding of molecular pathology and treatment of cardiomyopathy in duchenne muscular dystrophyGenetic evidence in the mouse solidifies the calcium hypothesis of myofiber death in muscular dystrophySTAT3 promotes IFNγ/TNFα-induced muscle wasting in an NF-κB-dependent and IL-6-independent manner.S-nitrosoglutathione reductase deficiency-induced S-nitrosylation results in neuromuscular dysfunction.Src-dependent impairment of autophagy by oxidative stress in a mouse model of Duchenne muscular dystrophyElectrical stimuli are anti-apoptotic in skeletal muscle via extracellular ATP. Alteration of this signal in Mdx mice is a likely cause of dystrophy.Nifedipine treatment reduces resting calcium concentration, oxidative and apoptotic gene expression, and improves muscle function in dystrophic mdx mice.Whole body periodic acceleration is an effective therapy to ameliorate muscular dystrophy in mdx mice.Altered ROS production, NF-κB activation and interleukin-6 gene expression induced by electrical stimulation in dystrophic mdx skeletal muscle cellsThe NF-κB p65 and p50 homodimer cooperate with IRF8 to activate iNOS transcription.Phospholamban overexpression in mice causes a centronuclear myopathy-like phenotype.Role of Ryanodine and NMDA Receptors in Tetrabromobisphenol A-Induced Calcium Imbalance and Cytotoxicity in Primary Cultures of Rat Cerebellar Granule Cells.Sarcolipin deletion exacerbates soleus muscle atrophy and weakness in phospholamban overexpressing mice.Absence of Dystrophin Disrupts Skeletal Muscle Signaling: Roles of Ca2+, Reactive Oxygen Species, and Nitric Oxide in the Development of Muscular Dystrophy.AMPK, a metabolic sensor, is involved in isoeugenol-induced glucose uptake in muscle cells.The plasma membrane calcium ATPase 4 signalling in cardiac fibroblasts mediates cardiomyocyte hypertrophyWasting mechanisms in muscular dystrophy.Partial least squares based identification of Duchenne muscular dystrophy specific genes.Subanesthetic isoflurane relieves zymosan-induced neutrophil inflammatory response by targeting NMDA glutamate receptor and Toll-like receptor 2 signalingDysregulation of calcium homeostasis in muscular dystrophies.Drug Discovery of Therapies for Duchenne Muscular Dystrophy.Dose-Dependent Responses of I3C and DIM on T-Cell Activation in the Human T Lymphocyte Jurkat Cell Line.Activation of osmolyte pathways in inflammatory myopathy and Duchenne muscular dystrophy points to osmoregulation as a contributing pathogenic mechanism.Electrical stimulation induces IL-6 in skeletal muscle through extracellular ATP by activating Ca(2+) signals and an IL-6 autocrine loop.Unveiling transcription factor regulation and differential co-expression genes in Duchenne muscular dystrophy.Na+ dysregulation coupled with Ca2+ entry through NCX1 promotes muscular dystrophy in mice.Second-generation compound for the modulation of utrophin in the therapy of DMD.Melatonin Has An Ergogenic Effect But Does Not Prevent Inflammation and Damage In Exhaustive Exercise.NOX2 Inhibition Impairs Early Muscle Gene Expression Induced by a Single Exercise Bout.Fast skeletal myofibers of mdx mouse, model of Duchenne muscular dystrophy, express connexin hemichannels that lead to apoptosis.Age-dependent changes in diastolic Ca(2+) and Na(+) concentrations in dystrophic cardiomyopathy: Role of Ca(2+) entry and IP3.Dysregulation of Intracellular Ca2+ in Dystrophic Cortical and Hippocampal Neurons.Strenuous exercise triggers a life-threatening response in mice susceptible to malignant hyperthermia.
P2860
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P2860
Increased resting intracellular calcium modulates NF-κB-dependent inducible nitric-oxide synthase gene expression in dystrophic mdx skeletal myotubes
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Increased resting intracellula ...... strophic mdx skeletal myotubes
@ast
Increased resting intracellula ...... strophic mdx skeletal myotubes
@en
type
label
Increased resting intracellula ...... strophic mdx skeletal myotubes
@ast
Increased resting intracellula ...... strophic mdx skeletal myotubes
@en
prefLabel
Increased resting intracellula ...... strophic mdx skeletal myotubes
@ast
Increased resting intracellula ...... strophic mdx skeletal myotubes
@en
P2093
P2860
P356
P1476
Increased resting intracellula ...... strophic mdx skeletal myotubes
@en
P2093
Enrique Jaimovich
Jose R López
Paul D Allen
Tadeusz Molinski
P2860
P304
20876-20887
P356
10.1074/JBC.M112.344929
P407
P577
2012-05-01T00:00:00Z