Detrimental role for human high temperature requirement serine protease A1 (HTRA1) in the pathogenesis of intervertebral disc (IVD) degeneration.
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Correlation Between Expression of High Temperature Requirement Serine Protease A1 (HtrA1) in Nucleus Pulposus and T2 Value of Magnetic Resonance ImagingFibronectin fragments and the cleaving enzyme ADAM-8 in the degenerative human intervertebral disc.Borrelia burgdorferi HtrA may promote dissemination and irritationActivation of intervertebral disc cells by co-culture with notochordal cells, conditioned medium and hypoxia.Organ culture bioreactors--platforms to study human intervertebral disc degeneration and regenerative therapy.Angiographic features of transgenic mice with increased expression of human serine protease HTRA1 in retinal pigment epitheliumSerum levels of the proinflammatory cytokine interleukin-6 vary based on diagnoses in individuals with lumbar intervertebral disc diseases.Transcriptomic Determinants of Scrapie Prion Propagation in Cultured Ovine Microglia.Nerve Growth Factor Is Regulated by Toll-Like Receptor 2 in Human Intervertebral DiscsSyndecan-4 in intervertebral disc and cartilage: Saint or synner?Chondroadherin fragmentation mediated by the protease HTRA1 distinguishes human intervertebral disc degeneration from normal aging.Gene expression profile analysis of human intervertebral disc degeneration.Inflammatory mediators in intervertebral disk degeneration and discogenic pain.Hyaluronic acid fragments enhance the inflammatory and catabolic response in human intervertebral disc cells through modulation of toll-like receptor 2 signalling pathways.Biochemical composition and turnover of the extracellular matrix of the normal and degenerate intervertebral disc.Role of HTRA1 in bone formation and regeneration: In vitro and in vivo evaluation.The roles and perspectives of microRNAs as biomarkers for intervertebral disc degeneration.Overexpression of HTRA1 leads to down-regulation of fibronectin and functional changes in RF/6A cells and HUVECs.Novel Function of Serine Protease HTRA1 in Inhibiting Adipogenic Differentiation of Human Mesenchymal Stem Cells via MAP Kinase-Mediated MMP Upregulation.An Inflammatory Nucleus Pulposus Tissue Culture Model to Test Molecular Regenerative Therapies: Validation with Epigallocatechin 3-Gallate.Borrelia burgdorferi BbHtrA degrades host ECM proteins and stimulates release of inflammatory cytokines in vitro.Toll-like Receptor Activation Induces Degeneration of Human Intervertebral Discs.ER stress-induced aggresome trafficking of HtrA1 protects against proteotoxicity.Simvastatin Inhibits IL-1β-Induced Apoptosis and Extracellular Matrix Degradation by Suppressing the NF-kB and MAPK Pathways in Nucleus Pulposus Cells.VEGF vascularization pathway in human intervertebral disc does not change during the disc degeneration process.Link N is cleaved by human annulus fibrosus cells generating a fragment with retained biological activityExpression and regulation of toll-like receptors (TLRs) in human intervertebral disc cells
P2860
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P2860
Detrimental role for human high temperature requirement serine protease A1 (HTRA1) in the pathogenesis of intervertebral disc (IVD) degeneration.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Detrimental role for human hig ...... ebral disc (IVD) degeneration.
@ast
Detrimental role for human hig ...... ebral disc (IVD) degeneration.
@en
type
label
Detrimental role for human hig ...... ebral disc (IVD) degeneration.
@ast
Detrimental role for human hig ...... ebral disc (IVD) degeneration.
@en
prefLabel
Detrimental role for human hig ...... ebral disc (IVD) degeneration.
@ast
Detrimental role for human hig ...... ebral disc (IVD) degeneration.
@en
P2093
P2860
P50
P356
P1476
Detrimental role for human hig ...... ebral disc (IVD) degeneration.
@en
P2093
Ali Mirsaidi
André N Tiaden
Gregor Bahrenberg
Lilian Quero
Marina Klawitter
Peter J Richards
Stephan Glanz
P2860
P304
21335-21345
P356
10.1074/JBC.M112.341032
P407
P577
2012-05-03T00:00:00Z