Structural determinant for inducing RORgamma specific inverse agonism triggered by a synthetic benzoxazinone ligand.
about
Structural studies unravel the active conformation of apo RORγt nuclear receptor and a common inverse agonism of two diverse classes of RORγt inhibitors.Structural States of RORγt: X-ray Elucidation of Molecular Mechanisms and Binding Interactions for Natural and Synthetic Compounds.Ternary complex of human RORγ ligand-binding domain, inverse agonist and SMRT peptide shows a unique mechanism of corepressor recruitment.
P2860
Structural determinant for inducing RORgamma specific inverse agonism triggered by a synthetic benzoxazinone ligand.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
Structural determinant for ind ...... ynthetic benzoxazinone ligand.
@ast
Structural determinant for ind ...... ynthetic benzoxazinone ligand.
@en
type
label
Structural determinant for ind ...... ynthetic benzoxazinone ligand.
@ast
Structural determinant for ind ...... ynthetic benzoxazinone ligand.
@en
prefLabel
Structural determinant for ind ...... ynthetic benzoxazinone ligand.
@ast
Structural determinant for ind ...... ynthetic benzoxazinone ligand.
@en
P2093
P2860
P1476
Structural determinant for ind ...... synthetic benzoxazinone ligand
@en
P2093
Craig P Wildes
Douglas J Marcotte
Jayanth V Chodaparambil
John H Jones
Kevin Little
Noel A Powell
YuTing Liu
P2860
P2888
P356
10.1186/S12900-016-0059-3
P577
2016-06-01T00:00:00Z
P6179
1016037734