Altered γ-secretase activity in mild cognitive impairment and Alzheimer's disease.
about
γ-secretase binding sites in aged and Alzheimer's disease human cerebrum: the choroid plexus as a putative origin of CSF AβIncreased γ-secretase activity in idiopathic normal pressure hydrocephalus patients with β-amyloid pathology.The pathogenic aβ43 is enriched in familial and sporadic Alzheimer diseaseMechanism of intramembrane cleavage of alcadeins by γ-secretase.Qualitative changes in human γ-secretase underlie familial Alzheimer's disease.Cerebrospinal fluid neurogranin and YKL-40 as biomarkers of Alzheimer's disease.Hyperpolarization-activated cyclic nucleotide gated channels: a potential molecular link between epileptic seizures and Aβ generation in Alzheimer's diseaseCerebrospinal Fluid Levels of Amyloid Beta 1-43 in Patients with Amnestic Mild Cognitive Impairment or Early Alzheimer's Disease: A 2-Year Follow-Up Study.CSF Presenilin-1 complexes are increased in Alzheimer's diseaseCerebrospinal Fluid Levels of Amyloid Beta 1-43 Mirror 1-42 in Relation to Imaging Biomarkers of Alzheimer's Disease.Deregulation of excitatory neurotransmission underlying synapse failure in Alzheimer's disease.Novel disease-modifying therapeutics for the treatment of Alzheimer's disease.Alanine substitutions in the GXXXG motif alter C99 cleavage by γ-secretase but not its dimerization.Distinct deposition of amyloid-β species in brains with Alzheimer's disease pathology visualized with MALDI imaging mass spectrometry.Processing of the platelet amyloid precursor protein in the mild cognitive impairment (MCI).Genetic Variation in δ-Opioid Receptor Associates with Increased β- and γ-Secretase Activity in the Late Stages of Alzheimer's Disease.Cross-seeding between Aβ40 and Aβ42 in Alzheimer's disease.Cerebrospinal fluid levels of phosphorylated tau and Aβ1-38/Aβ1-40/Aβ1-42 in Alzheimer's disease with PS1 mutations.
P2860
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P2860
Altered γ-secretase activity in mild cognitive impairment and Alzheimer's disease.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Altered γ-secretase activity in mild cognitive impairment and Alzheimer's disease.
@ast
Altered γ-secretase activity in mild cognitive impairment and Alzheimer's disease.
@en
type
label
Altered γ-secretase activity in mild cognitive impairment and Alzheimer's disease.
@ast
Altered γ-secretase activity in mild cognitive impairment and Alzheimer's disease.
@en
prefLabel
Altered γ-secretase activity in mild cognitive impairment and Alzheimer's disease.
@ast
Altered γ-secretase activity in mild cognitive impairment and Alzheimer's disease.
@en
P2093
P2860
P356
P1476
Altered γ-secretase activity in mild cognitive impairment and Alzheimer's disease
@en
P2093
Hajime Arai
Haruyasu Yamaguchi
Hiroyuki Arai
Hiroyuki Hatsuta
Japanese Alzheimer's Disease Neuroimaging Initiative
Katsutoshi Furukawa
Kazuhiro Nagaike
Kohei Akazawa
Mako Takami
Masakazu Miyajima
P2860
P304
P356
10.1002/EMMM.201200214
P50
P577
2012-02-21T00:00:00Z