A Novel Assay to Measure the Magnitude of the Inducible Viral Reservoir in HIV-infected Individuals
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Viral markers for HIV cure trials: are we getting any closer?How to Define the Latent Reservoir: Tools of the TradeHow Much HIV is Alive? The Challenge of Measuring Replication Competent HIV for HIV Cure ResearchAre T cells the only HIV-1 reservoir?DNA/MVA Vaccination of HIV-1 Infected Participants with Viral Suppression on Antiretroviral Therapy, followed by Treatment Interruption: Elicitation of Immune Responses without Control of Re-Emergent VirusHumoral and Innate Antiviral Immunity as Tools to Clear Persistent HIV InfectionGenetically-barcoded SIV facilitates enumeration of rebound variants and estimation of reactivation rates in nonhuman primates following interruption of suppressive antiretroviral therapy.High-throughput Characterization of HIV-1 Reservoir Reactivation Using a Single-Cell-in-Droplet PCR Assay.Combined single-cell quantitation of host and SIV genes and proteins ex vivo reveals host-pathogen interactions in individual cellsA Novel Single-Cell FISH-Flow Assay Identifies Effector Memory CD4+ T cells as a Major Niche for HIV-1 Transcription in HIV-Infected Patients.Integrated and Total HIV-1 DNA Predict Ex Vivo Viral OutgrowthCD4+ T Cells Expressing PD-1, TIGIT and LAG-3 Contribute to HIV Persistence during ART.Anti-HIV Antibody Responses and the HIV Reservoir Size during Antiretroviral TherapyTranscriptomic Analysis Implicates the p53 Signaling Pathway in the Establishment of HIV-1 Latency in Central Memory CD4 T Cells in an In Vitro Model.Ex vivo activation of CD4+ T-cells from donors on suppressive ART can lead to sustained production of infectious HIV-1 from a subset of infected cellsMeasuring the latent reservoir in vivo.Animal models to achieve an HIV cureInternational AIDS Society global scientific strategy: towards an HIV cure 2016.Loss of immune homeostasis dictates SHIV rebound after stem-cell transplantation.A highly reproducible quantitative viral outgrowth assay for the measurement of the replication-competent latent HIV-1 reservoirCuring HIV: Moving Forward Faster.HIV-1 latent reservoir: size mattersHIV-1 Eradication: Early Trials (and Tribulations).Measuring the Size of the Latent Human Immunodeficiency Virus Reservoir: The Present and Future of Evaluating Eradication Strategies.Current views on HIV-1 latency, persistence, and cure.Strategies to limit immune-activation in HIV patients.The Alphabet Soup of HIV Reservoir Markers.A Critical Review of the Evidence Concerning the HIV Latency Reversing Effect of Disulfiram, the Possible Explanations for Its Inability to Reduce the Size of the Latent Reservoir In Vivo, and the Caveats Associated with Its Use in Practice.Proviral Latency, Persistent Human Immunodeficiency Virus Infection, and the Development of Latency Reversing Agents.Defective HIV-1 Proviruses Are Expressed and Can Be Recognized by Cytotoxic T Lymphocytes, which Shape the Proviral Landscape.Barriers to HIV remission research in low- and middle-income countries.RNA flow cytometric FISH for investigations into HIV immunology, vaccination and cure strategies.Multiparametric characterization of rare HIV-infected cells using an RNA-flow FISH technique.HDAC inhibition induces HIV-1 protein and enables immune-based clearance following latency reversal.Brain Macrophages in Simian Immunodeficiency Virus-Infected, Antiretroviral-Suppressed Macaques: a Functional Latent Reservoir.Novel assay reveals a large, inducible, replication-competent HIV-1 reservoir in resting CD4+ T cells.Relative efficacy of T cell stimuli as inducers of productive HIV-1 replication in latently infected CD4 lymphocytes from patients on suppressive cART.Human Immunodeficiency Virus Persistence and T-Cell Activation in Blood, Rectal, and Lymph Node Tissue in Human Immunodeficiency Virus-Infected Individuals Receiving Suppressive Antiretroviral Therapy.A humanized mouse-based HIV-1 viral outgrowth assay with higher sensitivity than in vitro qVOA in detecting latently infected cells from individuals on ART with undetectable viral loads.Ultrasensitive HIV-1 p24 Assay Detects Single Infected Cells and Differences in Reservoir Induction by Latency Reversal Agents.
P2860
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P2860
A Novel Assay to Measure the Magnitude of the Inducible Viral Reservoir in HIV-infected Individuals
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
A Novel Assay to Measure the M ...... ir in HIV-infected Individuals
@ast
A Novel Assay to Measure the M ...... ir in HIV-infected Individuals
@en
type
label
A Novel Assay to Measure the M ...... ir in HIV-infected Individuals
@ast
A Novel Assay to Measure the M ...... ir in HIV-infected Individuals
@en
prefLabel
A Novel Assay to Measure the M ...... ir in HIV-infected Individuals
@ast
A Novel Assay to Measure the M ...... ir in HIV-infected Individuals
@en
P2093
P2860
P50
P1433
P1476
A Novel Assay to Measure the M ...... ir in HIV-infected Individuals
@en
P2093
Anne-Gaelle Bebin
Daria J Hazuda
Deanna A Kulpa
Douglas D Richman
Francesco Andrea Procopio
Jessica H Brehm
Matthew C Strain
Michael D Miller
Rafick-Pierre Sékaly
Rebecca Hoh
P2860
P304
P356
10.1016/J.EBIOM.2015.06.019
P577
2015-06-27T00:00:00Z