bax-deficiency promotes drug resistance and oncogenic transformation by attenuating p53-dependent apoptosis.
about
Stra13 is induced by genotoxic stress and regulates ionizing-radiation-induced apoptosisCharacterization of cells and gene-targeted mice deficient for the p53-binding kinase homeodomain-interacting protein kinase 1 (HIPK1)Noxa in colorectal cancer: a study on DNA, mRNA and protein expressionPUMA mediates the apoptotic response to p53 in colorectal cancer cellsPERP, an apoptosis-associated target of p53, is a novel member of the PMP-22/gas3 familyBok is a pro-apoptotic Bcl-2 protein with restricted expression in reproductive tissues and heterodimerizes with selective anti-apoptotic Bcl-2 family membersAssociation of Ubc9, an E2 ligase for SUMO conjugation, with p53 is regulated by phosphorylation of p53Zinc oxide nanoparticles-induced epigenetic change and G2/M arrest are associated with apoptosis in human epidermal keratinocytesEssential contribution of caspase 3/CPP32 to apoptosis and its associated nuclear changesAtm and Bax cooperate in ionizing radiation-induced apoptosis in the central nervous systemIntegral role of Noxa in p53-mediated apoptotic responseBax loss impairs Myc-induced apoptosis and circumvents the selection of p53 mutations during Myc-mediated lymphomagenesisDamage-induced apoptosis in intestinal epithelia from bcl-2-null and bax-null mice: investigations of the mechanistic determinants of epithelial apoptosis in vivoGlucose uptake and glycolysis reduce hypoxia-induced apoptosis in cultured neonatal rat cardiac myocytes.Impaired BAX protein expression in breast cancer: mutational analysis of the BAX and the p53 gene.Analysis of p53/BAX in primary colorectal carcinoma: low BAX protein expression is a negative prognostic factor in UICC stage III tumors.Multigene analysis of Rb pathway and apoptosis control in esophageal squamous cell carcinoma identifies patients with good prognosis.Sharp-1 modulates the cellular response to DNA damage.Induction of p53, p21 and apoptosis by silencing the NF90/NF45 complex in human papilloma virus-transformed cervical carcinoma cells.The p53 pathway and apoptosis.Characterization of structural p53 mutants which show selective defects in apoptosis but not cell cycle arrestRegulation of Mdm2-directed degradation by the C terminus of p53.Apoptosis in cancer.Inactivation of p21 by E1A leads to the induction of apoptosis in DNA-damaged cells.Boolean ErbB network reconstructions and perturbation simulations reveal individual drug response in different breast cancer cell lines.Bax-mediated cell death by the Gax homeoprotein requires mitogen activation but is independent of cell cycle activityWild-type and mutated presenilins 2 trigger p53-dependent apoptosis and down-regulate presenilin 1 expression in HEK293 human cells and in murine neurons.Grape proanthocyanidins induce apoptosis by loss of mitochondrial membrane potential of human non-small cell lung cancer cells in vitro and in vivoTissue specific expression of p53 target genes suggests a key role for KILLER/DR5 in p53-dependent apoptosis in vivo.Mechanisms of cell-cycle checkpoints: at the crossroads of carcinogenesis and drug discovery.Nuclear and mitochondrial apoptotic pathways of p53.p400 is required for E1A to promote apoptosis.Dysregulation of apoptosis and a novel mechanism of defective apoptotic signal transduction in human B-cell neoplasms.Grape seed proanthocyanidins induce apoptosis through p53, Bax, and caspase 3 pathways.Simian virus 40 large T antigen and two independent T-antigen segments sensitize cells to apoptosis following genotoxic damageBH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and BakQuinacrine Inhibits Cell Growth and Induces Apoptosis in Human Gastric Cancer Cell Line SGC-7901.Two novel determinants of etoposide resistance in small cell lung cancer.PML is induced by oncogenic ras and promotes premature senescenceE1A signaling to p53 involves the p19(ARF) tumor suppressor.
P2860
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P2860
bax-deficiency promotes drug resistance and oncogenic transformation by attenuating p53-dependent apoptosis.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
1997年學術文章
@zh
1997年學術文章
@zh-hant
name
bax-deficiency promotes drug r ...... ating p53-dependent apoptosis.
@ast
bax-deficiency promotes drug r ...... ating p53-dependent apoptosis.
@en
type
label
bax-deficiency promotes drug r ...... ating p53-dependent apoptosis.
@ast
bax-deficiency promotes drug r ...... ating p53-dependent apoptosis.
@en
prefLabel
bax-deficiency promotes drug r ...... ating p53-dependent apoptosis.
@ast
bax-deficiency promotes drug r ...... ating p53-dependent apoptosis.
@en
P2093
P2860
P356
P1476
bax-deficiency promotes drug r ...... ating p53-dependent apoptosis.
@en
P2093
C M Knudson
M E McCurrach
S J Korsmeyer
T M Connor
P2860
P304
P356
10.1073/PNAS.94.6.2345
P407
P577
1997-03-01T00:00:00Z