Mucus clearance, MyD88-dependent and MyD88-independent immunity modulate lung susceptibility to spontaneous bacterial infection and inflammation
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Neutrophil elastase and matrix metalloproteinase 12 in cystic fibrosis lung diseaseEarly pulmonary inflammation and lung damage in children with cystic fibrosisThe role of chitin, chitinases, and chitinase-like proteins in pediatric lung diseasesChronic alcohol ingestion changes the landscape of the alveolar epitheliumBarriers to inhaled gene therapy of obstructive lung diseases: A reviewCystic fibrosis: NHLBI Workshop on the Primary Prevention of Chronic Lung Diseases.Cystic fibrosis airway secretions exhibit mucin hyperconcentration and increased osmotic pressure.Lack of neutrophil elastase reduces inflammation, mucus hypersecretion, and emphysema, but not mucus obstruction, in mice with cystic fibrosis-like lung disease.Gene expression in whole lung and pulmonary macrophages reflects the dynamic pathology associated with airway surface dehydration.A biophysical basis for mucus solids concentration as a candidate biomarker for airways disease.Hypoxic epithelial necrosis triggers neutrophilic inflammation via IL-1 receptor signaling in cystic fibrosis lung disease.Cystic fibrosis: an inherited disease affecting mucin-producing organs.Genetically determined heterogeneity of lung disease in a mouse model of airway mucus obstruction.CFTR, mucins, and mucus obstruction in cystic fibrosis.Neonatal Pulmonary Macrophage Depletion Coupled to Defective Mucus Clearance Increases Susceptibility to Pneumonia and Alters Pulmonary Immune Responses.Loss of Cftr function exacerbates the phenotype of Na(+) hyperabsorption in murine airways.Hypertonic saline is effective in the prevention and treatment of mucus obstruction, but not airway inflammation, in mice with chronic obstructive lung diseaseUDP-glucose promotes neutrophil recruitment in the lung.Pseudomonas aeruginosa Airway Infection Recruits and Modulates Neutrophilic Myeloid-Derived Suppressor Cells.Pharmacological and genetic reappraisals of protease and oxidative stress pathways in a mouse model of obstructive lung diseases.Contribution of mucus concentration and secreted mucins Muc5ac and Muc5b to the pathogenesis of muco-obstructive lung diseaseEarly Postnatal Secondhand Smoke Exposure Disrupts Bacterial Clearance and Abolishes Immune Responses in Muco-Obstructive Lung Disease.Airway mucus, inflammation and remodeling: emerging links in the pathogenesis of chronic lung diseases.Mucus Hyperconcentration as a Unifying Aspect of the Chronic Bronchitic Phenotype.On the Pathogenesis of Acute Exacerbations of Mucoobstructive Lung Diseases.Mapping targetable inflammation and outcomes with cystic fibrosis biomarkers.Lung disease phenotypes caused by overexpression of combinations of α-, β-, and γ-subunits of the epithelial sodium channel in mouse airways.Airway disease phenotypes in animal models of cystic fibrosis.Effect of LysM+ macrophage depletion on lung pathology in mice with chronic bronchitis.
P2860
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P2860
Mucus clearance, MyD88-dependent and MyD88-independent immunity modulate lung susceptibility to spontaneous bacterial infection and inflammation
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Mucus clearance, MyD88-depende ...... ial infection and inflammation
@ast
Mucus clearance, MyD88-depende ...... ial infection and inflammation
@en
type
label
Mucus clearance, MyD88-depende ...... ial infection and inflammation
@ast
Mucus clearance, MyD88-depende ...... ial infection and inflammation
@en
prefLabel
Mucus clearance, MyD88-depende ...... ial infection and inflammation
@ast
Mucus clearance, MyD88-depende ...... ial infection and inflammation
@en
P2093
P2860
P356
P1433
P1476
Mucus clearance, MyD88-depende ...... ial infection and inflammation
@en
P2093
A Livraghi-Butrico
M C Wolfgang
R C Boucher
S H Randell
W K O'Neal
P2860
P2888
P304
P356
10.1038/MI.2012.17
P577
2012-03-14T00:00:00Z