about
p66Shc as a switch in bringing about contrasting responses in cell growth: implications on cell proliferation and apoptosisDistinct signaling functions for Shc isoforms in the heartAntagonism of p66shc by melanoma inhibitory activity.Cytochrome c signalosome in mitochondria.Identification of Peroxiredoxin 1 as a novel interaction partner for the lifespan regulator protein p66Shc.p66shc inhibits insulin-like growth factor-I signaling via direct binding to Src through its polyproline and Src homology 2 domains, resulting in impairment of Src kinase activation.p66Shc longevity protein regulates the proliferation of human ovarian cancer cellsp66Shc--a longevity redox protein in human prostate cancer progression and metastasis : p66Shc in cancer progression and metastasis.The influence of Shc proteins on life span in mice.RBMS3 at 3p24 inhibits nasopharyngeal carcinoma development via inhibiting cell proliferation, angiogenesis, and inducing apoptosisDecoding the oxidative stress hypothesis in diabetic embryopathy through proapoptotic kinase signaling.Smoking p66Shc knocked out mice develop respiratory bronchiolitis with fibrosis but not emphysemaDiallyl trisulfide-induced prostate cancer cell death is associated with Akt/PKB dephosphorylation mediated by P-p66shc.p66Shc, oxidative stress and aging: importing a lifespan determinant into mitochondriap66shc negatively regulates insulin-like growth factor I signal transduction via inhibition of p52shc binding to Src homology 2 domain-containing protein tyrosine phosphatase substrate-1 leading to impaired growth factor receptor-bound protein-2 memThe versatility of mitochondrial calcium signals: from stimulation of cell metabolism to induction of cell death.Teaching an old dogma new tricks: twenty years of Shc adaptor signalling.Oxidative stress, a common molecular pathway for kidney disease: role of the redox enzyme p66Shc.Mortalin, apoptosis, and neurodegeneration.Ouabain elicits human glioblastoma cells apoptosis by generating reactive oxygen species in ERK-p66SHC-dependent pathway.Role of p66shc in renal toxicity of oleic acid.p66shc inhibits pro-survival epidermal growth factor receptor/ERK signaling during severe oxidative stress in mouse renal proximal tubule cells.Induction of uPA gene expression by the blockage of E-cadherin via Src- and Shc-dependent Erk signaling.Integrin signaling, cell survival, and anoikis: distinctions, differences, and differentiation.p66(Shc) has a pivotal function in impaired liver regeneration in aged mice by a redox-dependent mechanism.Sublethal heat treatment promotes epithelial-mesenchymal transition and enhances the malignant potential of hepatocellular carcinoma.Elevated p66Shc is associated with intracellular redox imbalance in developmentally compromised bovine embryos.Coenzyme Q10 protects renal proximal tubule cells against nicotine-induced apoptosis through induction of p66shc-dependent antioxidant responses.Differential expression of senescence and cell death factors in non-small cell lung and colorectal tumors showing telomere attrition.Liver regeneration in aged mice: new insights
P2860
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P2860
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
p66SHC: the apoptotic side of Shc proteins.
@ast
p66SHC: the apoptotic side of Shc proteins.
@en
type
label
p66SHC: the apoptotic side of Shc proteins.
@ast
p66SHC: the apoptotic side of Shc proteins.
@en
prefLabel
p66SHC: the apoptotic side of Shc proteins.
@ast
p66SHC: the apoptotic side of Shc proteins.
@en
P2093
P1433
P1476
p66SHC: the apoptotic side of Shc proteins.
@en
P2093
C T Baldari
M Pellegrini
P2860
P2888
P356
10.1007/S10495-005-6057-8
P577
2005-01-01T00:00:00Z