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Methods for reliability and uncertainty assessment and for applicability evaluations of classification- and regression-based QSARsComparison of in vivo (Draize method) and in vitro (Corrositex assay) dermal corrosion values for selected industrial chemicalsAn in vitro alveolar macrophage assay for predicting the short-term inhalation toxicity of nanomaterialsPrediction of chemical respiratory sensitizers using GARD, a novel in vitro assay based on a genomic biomarker signatureSelf organising hypothesis networks: a new approach for representing and structuring SAR knowledgeNew public QSAR model for carcinogenicity.Test battery with the human cell line activation test, direct peptide reactivity assay and DEREK based on a 139 chemical data set for predicting skin sensitizing potential and potency of chemicals.Toxicological and clinical computational analysis and the US FDA/CDER.Filling the concept with data: integrating data from different in vitro and in silico assays on skin sensitizers to explore the battery approach for animal-free skin sensitization testing.Skin sensitizers induce antioxidant response element dependent genes: application to the in vitro testing of the sensitization potential of chemicals.Comparison between carcinogenicity and mutagenicity based on chemicals evaluated in the IARC monographs.Inter-species comparisons of carcinogenicity.In Silico Prediction of Caco-2 Cell Permeability by a Classification QSAR Approach.Chemicals showing no evidence of carcinogenicity in long-term, two-species rodent studies: the need for short-term test data.Prediction of N-Methyl-D-Aspartate Receptor GluN1-Ligand Binding Affinity by a Novel SVM-Pose/SVM-Score Combinatorial Ensemble Docking SchemeHow accurate is in vitro prediction of carcinogenicity?(Q)SAR modeling and safety assessment in regulatory review.Nonlinear QSAR modeling for predicting cytotoxicity of ionic liquids in leukemia rat cell line: an aid to green chemicals designing.Genomic allergen rapid detection in-house validation--a proof of concept.Performance of comet and micronucleus assays in metabolic competent HepaRG cells to predict in vivo genotoxicity.Construction and Consensus Performance of (Q)SAR Models for Predicting Phospholipidosis Using a Dataset of 743 Compounds.Using In Silico Tools in a Weight of Evidence Approach to Aid Toxicological Assessment.Analysis of 75 marketed pharmaceuticals using the GADD45a-GFP 'GreenScreen HC' genotoxicity assay.Identification of Structurally Diverse Antimicrobials Through Sequential Application of Pharmacophore Modeling, Virtual Screening, Molecular Docking and In Vitro Microbiological Assay.Predicting binding affinities of diverse pharmaceutical chemicals to human serum plasma proteins using QSPR modelling approaches.Application of transformation systems.Investigating hydrochemistry of groundwater in Indo-Gangetic alluvial plain using multivariate chemometric approaches.An investigation of new toxicity test method performance in validation studies: 1. Toxicity test methods that have predictive capacity no greater than chance.Modeling the binding affinity of structurally diverse industrial chemicals to carbon using the artificial intelligence approaches.Estimating sensory irritation potency of volatile organic chemicals using QSARs based on decision tree methods for regulatory purpose.Qualitative and quantitative structure-activity relationship modelling for predicting blood-brain barrier permeability of structurally diverse chemicals.The ability of short-term tests to predict carcinogenicity can be summarized in a single index.Predictivity approach for quantitative structure-property models. Application for blood-brain barrier permeation of diverse drug-like compounds.A medium-term, rapid rat bioassay model for the detection of carcinogenic potential of chemicals.A Novel Strategy to Predict Carcinogenicity of Antiparasitics Based on a Combination of DNA Lesions and Bacterial Mutagenicity Tests.Blue-yellow colour vision impairment and cognitive deficits in occasional and dependent stimulant users.QSAR models for P450 (2D6) substrate activity.Development of cardiac safety translational tools for QT prolongation and torsade de pointes.QSAR classification models for the screening of the endocrine-disrupting activity of perfluorinated compounds.Binary classification models for endocrine disrupter effects mediated through the estrogen receptor.
P2860
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P2860
description
1979 nî lūn-bûn
@nan
1979年の論文
@ja
1979年論文
@yue
1979年論文
@zh-hant
1979年論文
@zh-hk
1979年論文
@zh-mo
1979年論文
@zh-tw
1979年论文
@wuu
1979年论文
@zh
1979年论文
@zh-cn
name
Describing the validity of carcinogen screening tests.
@ast
Describing the validity of carcinogen screening tests.
@en
type
label
Describing the validity of carcinogen screening tests.
@ast
Describing the validity of carcinogen screening tests.
@en
prefLabel
Describing the validity of carcinogen screening tests.
@ast
Describing the validity of carcinogen screening tests.
@en
P2093
P2860
P356
P1476
Describing the validity of carcinogen screening tests.
@en
P2093
P2860
P2888
P356
10.1038/BJC.1979.10
P407
P577
1979-01-01T00:00:00Z