Hypoxia stabilizes GAS6/Axl signaling in metastatic prostate cancer. - Wikidata - wikimedia - TriplyDB

Hypoxia stabilizes GAS6/Axl signaling in metastatic prostate cancer.

Hypoxia stabilizes GAS6/Axl signaling in metastatic prostate cancer.

http://www.wikidata.org/entity/Q36044487

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Targeting hypoxic response for cancer therapy Disseminated tumor cells and dormancy in prostate cancer metastasis Progress toward overcoming hypoxia-induced resistance to solid tumor therapy AXL kinase as a novel target for cancer therapy The Receptor Tyrosine Kinase AXL in Cancer Progression Cancer Cell Colonisation in the Bone Microenvironment Hypoxia-inducing factors as master regulators of stemness properties and altered metabolism of cancer- and metastasis-initiating cells The role of epithelial plasticity in prostate cancer dissemination and treatment resistance Axl as a mediator of cellular growth and survival GAS6 receptor status is associated with dormancy and bone metastatic tumor formation Strong Expression of Hypoxia-Inducible Factor-1α (HIF-1α) Is Associated with Axl Expression and Features of Aggressive Tumors in African Breast Cancer.Vitamin K-dependent proteins GAS6 and Protein S and TAM receptors in patients of systemic lupus erythematosus: correlation with common genetic variants and disease activity Endogenous GAS6 and Mer receptor signaling regulate prostate cancer stem cells in bone marrow.Preclinical validation of AXL receptor as a target for antibody-based pancreatic cancer immunotherapy.The marrow niche controls the cancer stem cell phenotype of disseminated prostate cancer.AXL modulates extracellular matrix protein expression and is essential for invasion and metastasis in endometrial cancer.Molecular insights of Gas6/TAM in cancer development and therapy.New therapeutic targets for cancer bone metastasis Immunogenic, cellular, and angiogenic drivers of tumor dormancy--a melanoma view.Rat Prostate Tumor Cells Progress in the Bone Microenvironment to a Highly Aggressive Phenotype.Axl and Mer Receptor Tyrosine Kinases: Distinct and Nonoverlapping Roles in Inflammation and Cancer?The Relationship Between Dormant Cancer Cells and Their Microenvironment.Biochemical Changes in the Niche Following Tumor Cell Invasion.Key Roles of AXL and MER Receptor Tyrosine Kinases in Resistance to Multiple Anticancer Therapies.Changes in plasma biomarkers following treatment with cabozantinib in metastatic castration-resistant prostate cancer: a post hoc analysis of an extension cohort of a phase II trial.Phospho-AXL is widely expressed in glioblastoma and associated with significant shorter overall survival.Targeting Gas6/TAM in cancer cells and tumor microenvironment.AXL is a marker for epithelial-mesenchymal transition in esophageal squamous cell carcinoma.Axl mediates tumor invasion and chemosensitivity through PI3K/Akt signaling pathway and is transcriptionally regulated by slug in breast carcinoma.Mesenchymal Stromal Cells: Emerging Roles in Bone Metastasis.Reawakening of dormant estrogen-dependent human breast cancer cells by bone marrow stroma secretory senescence

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P2860

Hypoxia stabilizes GAS6/Axl signaling in metastatic prostate cancer.

http://www.wikidata.org/entity/Q36044487

description

2012 nî lūn-bûn

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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2012年论文

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2012年论文

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name

Hypoxia stabilizes GAS6/Axl signaling in metastatic prostate cancer.

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Hypoxia stabilizes GAS6/Axl signaling in metastatic prostate cancer.

@en

type

label

Hypoxia stabilizes GAS6/Axl signaling in metastatic prostate cancer.

@ast

Hypoxia stabilizes GAS6/Axl signaling in metastatic prostate cancer.

@en

prefLabel

Hypoxia stabilizes GAS6/Axl signaling in metastatic prostate cancer.

@ast

Hypoxia stabilizes GAS6/Axl signaling in metastatic prostate cancer.

@en

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1541-7786.MCR-11-0569

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Molecular Cancer Research

P1476

Hypoxia stabilizes GAS6/Axl signaling in metastatic prostate cancer.

@en

P2093

Aaron Havens

http://www.w3.org/2001/XMLSchema#string

Anjali Mishra

http://www.w3.org/2001/XMLSchema#string

Janice E Berry

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Jeena Joseph

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Jingcheng Wang

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Jinkoo Kim

http://www.w3.org/2001/XMLSchema#string

Samantha McGee

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Younghun Jung

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Yusuke Shiozawa

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P2860

The protein encoded by a growth arrest-specific gene (gas6) is a new member of the vitamin K-dependent proteins related to protein S, a negative coregulator in the blood coagulation cascade

Axl receptor tyrosine kinase stimulated by the vitamin K-dependent protein encoded by growth-arrest-specific gene 6

GAS6/Mer axis regulates the homing and survival of the E2A/PBX1-positive B-cell precursor acute lymphoblastic leukemia in the bone marrow niche

Dominant-negative inhibition of the Axl receptor tyrosine kinase suppresses brain tumor cell growth and invasion and prolongs survival

The basics of epithelial-mesenchymal transition

A novel putative tyrosine kinase receptor with oncogenic potential

Identification of the product of growth arrest-specific gene 6 as a common ligand for Axl, Sky, and Mer receptor tyrosine kinases

The transforming receptor tyrosine kinase, Axl, is post-translationally regulated by proteolytic cleavage

Cancer statistics, 2007

Metastasis to bone: causes, consequences and therapeutic opportunities

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10.1158/1541-7786.MCR-11-0569

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6

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10

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Russell S. Taichman

Kenneth J. Pienta

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2012-04-19T00:00:00Z

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22516347

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