Hyperglycemia and a common variant of GCKR are associated with the levels of eight amino acids in 9,369 Finnish men - Wikidata - wikimedia - TriplyDB

Hyperglycemia and a common variant of GCKR are associated with the levels of eight amino acids in 9,369 Finnish men

Hyperglycemia and a common variant of GCKR are associated with the levels of eight amino acids in 9,369 Finnish men

http://www.wikidata.org/entity/Q36047495

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TATN-1 mutations reveal a novel role for tyrosine as a metabolic signal that influences developmental decisions and longevity in Caenorhabditis elegans Novel methodologies for biomarker discovery in atherosclerosis Branched-chain amino acids in metabolic signalling and insulin resistance Biomarkers for type 2 diabetes and impaired fasting glucose using a nontargeted metabolomics approach The systems genetics resource: a web application to mine global data for complex disease traits.A central role for GRB10 in regulation of islet function in man.Amino Acid Signatures to Evaluate the Beneficial Effects of Weight Loss.Development and characterization of an experimental model of diet-induced metabolic syndrome in rabbit.Multi-tissue computational modeling analyzes pathophysiology of type 2 diabetes in MKR mice.Pleiotropic genes for metabolic syndrome and inflammation Metabolite traits and genetic risk provide complementary information for the prediction of future type 2 diabetes.Glutamine stimulates biosynthesis and secretion of insulin-like growth factor 2 (IGF2), an autocrine regulator of beta cell mass and function.Metabolomics in Prediabetes and Diabetes: A Systematic Review and Meta-analysis.A metabolomic study on the effect of intravascular laser blood irradiation on type 2 diabetic patients.Novel metabolic markers for the risk of diabetes development in American Indians.Metabolomic profile associated with insulin resistance and conversion to diabetes in the Insulin Resistance Atherosclerosis Study Metabolite profiling and cardiovascular event risk: a prospective study of 3 population-based cohorts.Diabetes risk and amino acid profiles: cross-sectional and prospective analyses of ethnicity, amino acids and diabetes in a South Asian and European cohort from the SABRE (Southall And Brent REvisited) Study.Genetic Variation Determines PPARγ Function and Anti-diabetic Drug Response In Vivo.Metabolomic Profiles of Body Mass Index in the Framingham Heart Study Reveal Distinct Cardiometabolic Phenotypes.Mechanisms Linking the Gut Microbiome and Glucose Metabolism.Alanine and aspartate aminotransferase and glutamine-cycling pathway: their roles in pathogenesis of metabolic syndrome.Effect of Insulin Resistance on Monounsaturated Fatty Acid Levels: A Multi-cohort Non-targeted Metabolomics and Mendelian Randomization Study Metabolic profiling of pregnancy: cross-sectional and longitudinal evidence.A pilot, short-term dietary manipulation of branched chain amino acids has modest influence on fasting levels of branched chain amino acids Metabolic effects of a 13-weeks lifestyle intervention in older adults: The Growing Old Together Study.Integrative approaches for large-scale transcriptome-wide association studies Branched-chain and aromatic amino acids are predictors of insulin resistance in young adults Metabolite Profiles of Diabetes Incidence and Intervention Response in the Diabetes Prevention Program.Serum metabolic biomarkers distinguish metabolically healthy peripherally obese from unhealthy centrally obese individuals.Histidine augments the suppression of hepatic glucose production by central insulin action.Relationship between Branched-Chain Amino Acids, Metabolic Syndrome, and Cardiovascular Risk Profile in a Chinese Population: A Cross-Sectional Study.Association of ketone body levels with hyperglycemia and type 2 diabetes in 9,398 Finnish men.Branched chain and aromatic amino acids change acutely following two medical therapies for type 2 diabetes mellitus.Insulin resistance in prepubertal obese children correlates with sex-dependent early onset metabolomic alterations.Effects of sleep restriction on the human plasma metabolome.RBC deformability and amino acid concentrations after hypo-osmotic challenge may reflect chronic cell hydration status in healthy young men.Metabolic profiling of alcohol consumption in 9778 young adults Metabolomics reveals broad-scale metabolic perturbations in hyperglycemic mothers during pregnancy Integrative mutation, haplotype and G × G interaction evidence connects ABGL4, LRP8 and PCSK9 genes to cardiometabolic risk.

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P2860

Hyperglycemia and a common variant of GCKR are associated with the levels of eight amino acids in 9,369 Finnish men

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P2860

Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

Dietary leucine--an environmental modifier of insulin resistance acting on multiple levels of metabolism

A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

Plasma metabolomic profiles reflective of glucose homeostasis in non-diabetic and type 2 diabetic obese African-American women

Genome-wide association studies in type 2 diabetes

Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge

Metabolite profiles and the risk of developing diabetes

A re-annotation pipeline for Illumina BeadArrays: improving the interpretation of gene expression data.

Role of glutamine in human carbohydrate metabolism in kidney and other tissues.

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