about
Non-cholesterol sterol levels predict hyperglycemia and conversion to type 2 diabetes in Finnish menMendelian randomization studies do not support a causal role for reduced circulating adiponectin levels in insulin resistance and type 2 diabetesCROPPER: a metagene creator resource for cross-platform and cross-species compendium studies.Integration of genomic data for pharmacology and toxicology using Internet resources.Common data elements and data management: Remedy to cure underpowered preclinical studies.FORG3D: force-directed 3D graph editor for visualization of integrated genome scale data.Identification of the UBP1 locus as a critical blood pressure determinant using a combination of mouse and human genetics.Indolepropionic acid and novel lipid metabolites are associated with a lower risk of type 2 diabetes in the Finnish Diabetes Prevention Study.TAFFEL: Independent Enrichment Analysis of gene sets.Whole grain products, fish and bilberries alter glucose and lipid metabolism in a randomized, controlled trial: the Sysdimet study.Varietas: a functional variation database portal.Genetic background of extreme violent behavior.Effects of whole grain, fish and bilberries on serum metabolic profile and lipid transfer protein activities: a randomized trial (Sysdimet).Effects of 34 risk loci for type 2 diabetes or hyperglycemia on lipoprotein subclasses and their composition in 6,580 nondiabetic Finnish men.Hyperglycemia and a common variant of GCKR are associated with the levels of eight amino acids in 9,369 Finnish menAnalysis of microarray studies performed in the neurosciences.Genetic variants associated with glycine metabolism and their role in insulin sensitivity and type 2 diabetesEffects of an isocaloric healthy Nordic diet on insulin sensitivity, lipid profile and inflammation markers in metabolic syndrome -- a randomized study (SYSDIET).Effects of a healthy Nordic diet on gene expression changes in peripheral blood mononuclear cells in response to an oral glucose tolerance test in subjects with metabolic syndrome: a SYSDIET sub-study.Association of ketone body levels with hyperglycemia and type 2 diabetes in 9,398 Finnish men.Association of 18 confirmed susceptibility loci for type 2 diabetes with indices of insulin release, proinsulin conversion, and insulin sensitivity in 5,327 nondiabetic Finnish men.Healthy Nordic diet downregulates the expression of genes involved in inflammation in subcutaneous adipose tissue in individuals with features of the metabolic syndrome.SEPT8 modulates β-amyloidogenic processing of APP by affecting the sorting and accumulation of BACE1.Relationship between ubiquilin-1 and BACE1 in human Alzheimer's disease and APdE9 transgenic mouse brain and cell-based models.Analysis of Post-Traumatic Brain Injury Gene Expression Signature Reveals Tubulins, Nfe2l2, Nfkb, Cd44, and S100a4 as Treatment Targets.A Healthy Nordic Diet Alters the Plasma Lipidomic Profile in Adults with Features of Metabolic Syndrome in a Multicenter Randomized Dietary Intervention.Dietary polyunsaturated fatty acids and the Pro12Ala polymorphisms of PPARG regulate serum lipids through divergent pathways: a randomized crossover clinical trial.Nontargeted metabolite profiling discriminates diet-specific biomarkers for consumption of whole grains, fatty fish, and bilberries in a randomized controlled trial.Identification and validation of N-acetyltransferase 2 as an insulin sensitivity gene.Genetic predisposition to obesity and lifestyle factors--the combined analyses of twenty-six known BMI- and fourteen known waist:hip ratio (WHR)-associated variants in the Finnish Diabetes Prevention Study.Lipoprotein subclass profiles in individuals with varying degrees of glucose tolerance: a population-based study of 9399 Finnish men.A dietary biomarker approach captures compliance and cardiometabolic effects of a healthy Nordic diet in individuals with metabolic syndrome.[Fatty fish modifies HDL particle size and lipid concentrations].Effects of Alzheimer's Disease-Associated Risk Loci on Amyloid-β Accumulation in the Brain of Idiopathic Normal Pressure Hydrocephalus Patients.The effects of a 2-year individualized and family-based lifestyle intervention on physical activity, sedentary behavior and diet in children.Association of the fat mass and obesity-associated (FTO) gene variant (rs9939609) with dietary intake in the Finnish Diabetes Prevention Study.Reduction in cardiometabolic risk factors by a multifunctional diet is mediated via several branches of metabolism as evidenced by nontargeted metabolite profiling approach.The postprandial plasma rye fingerprint includes benzoxazinoid-derived phenylacetamide sulfates.Association of indices of liver and adipocyte insulin resistance with 19 confirmed susceptibility loci for type 2 diabetes in 6,733 non-diabetic Finnish men.A novel surrogate index for hepatic insulin resistance.
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0000-0001-5100-4907