Hyaluronan and hyaluronan synthases: potential therapeutic targets in cancer.
about
The hyaluronan receptors CD44 and Rhamm (CD168) form complexes with ERK1,2 that sustain high basal motility in breast cancer cellsStudies on anticancer activities of antimicrobial peptidesRole of hyaluronan in pancreatic cancer biology and therapy: Once again in the spotlightInteractions between Hyaluronan and Its Receptors (CD44, RHAMM) Regulate the Activities of Inflammation and CancerThe roles of hyaluronan/RHAMM/CD44 and their respective interactions along the insidious pathways of fibrosarcoma progressionCD44, Hyaluronan, the Hematopoietic Stem Cell, and Leukemia-Initiating CellsCancer stem cells: the lessons from pre-cancerous stem cellsCD44v6 coordinates tumor matrix-triggered motility and apoptosis resistance.Quantitative continuous assay for hyaluronan synthaseA rapid transient increase in hyaluronan synthase-2 mRNA initiates secretion of hyaluronan by corneal keratocytes in response to transforming growth factor beta.Hyaluronan synthesis mediates the fibrotic response of keratocytes to transforming growth factor beta.Adenovirus-mediated gene transfer of mutated IkappaB kinase and IkappaBalpha reveal NF-kappaB-dependent as well as NF-kappaB-independent pathways of HAS1 activation.Hyaluronan synthase 3 variant and anthracycline-related cardiomyopathy: a report from the children's oncology group.Downregulation of CD44 reduces doxorubicin resistance of CD44CD24 breast cancer cellsRelationship between LYVE-1, VEGFR-3 and CD44 gene expressions and lymphatic metastasis in gastric cancer.Hyaluronan-CD44 interactions as potential targets for cancer therapy.Efficacy of the mineral oil and hyaluronic acid mixture eye drops in murine dry eye.Hyaluronan fragments as mediators of inflammation in allergic pulmonary diseaseThe JAK2/STAT3 signaling pathway is required for growth of CD44⁺CD24⁻ stem cell-like breast cancer cells in human tumors.Differentiation of breast cancer stem cells by knockdown of CD44: promising differentiation therapyInhibition of Hyaluronic Acid Synthesis Suppresses Angiogenesis in Developing Endometriotic Lesions.Rhamm-/- fibroblasts are defective in CD44-mediated ERK1,2 motogenic signaling, leading to defective skin wound repairBub1 is required for maintaining cancer stem cells in breast cancer cell linesTranscreener: screening enzymes involved in covalent regulation.The deubiquitinating enzymes USP4 and USP17 target hyaluronan synthase 2 and differentially affect its function.Loss of Glycogen Debranching Enzyme AGL Drives Bladder Tumor Growth via Induction of Hyaluronic Acid SynthesisHyaluronan fragments induce IFNβ via a novel TLR4-TRIF-TBK1-IRF3-dependent pathwayUsing neurofibromatosis-1 to better understand and treat pediatric low-grade gliomaGlycan antagonists and inhibitors: a fount for drug discovery.Role of hyaluronan in glioma invasion.Biochemical changes of extracellular proteoglycans in squamous cell laryngeal carcinoma.Aberrant splice variants of HAS1 (Hyaluronan Synthase 1) multimerize with and modulate normally spliced HAS1 protein: a potential mechanism promoting human cancerSonic hedgehog signaling directly targets Hyaluronic Acid Synthase 2, an essential regulator of phalangeal joint patterning.Role of the extracellular matrix in variations of invasive pathways in lung cancers.Alendronate enhances osteogenic differentiation of bone marrow stromal cells: a preliminary studyHyaluronan synthase 3 mediated oncogenic action through forming inter-regulation loop with tumor necrosis factor alpha in oral cancer.Three-dimensionally engineered biomimetic tissue models for in vitro drug evaluation: delivery, efficacy and toxicity.Tissue engineering concept in the research of the tumor biology.Deregulation of hyaluronan synthesis, degradation and binding promotes breast cancer.Delivery of CD44 shRNA/nanoparticles within cancer cells: perturbation of hyaluronan/CD44v6 interactions and reduction in adenoma growth in Apc Min/+ MICE.
P2860
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P2860
Hyaluronan and hyaluronan synthases: potential therapeutic targets in cancer.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Hyaluronan and hyaluronan synthases: potential therapeutic targets in cancer.
@ast
Hyaluronan and hyaluronan synthases: potential therapeutic targets in cancer.
@en
type
label
Hyaluronan and hyaluronan synthases: potential therapeutic targets in cancer.
@ast
Hyaluronan and hyaluronan synthases: potential therapeutic targets in cancer.
@en
prefLabel
Hyaluronan and hyaluronan synthases: potential therapeutic targets in cancer.
@ast
Hyaluronan and hyaluronan synthases: potential therapeutic targets in cancer.
@en
P356
P1476
Hyaluronan and hyaluronan synthases: potential therapeutic targets in cancer
@en
P2093
Linda M Pilarski
Sophia Adamia
P356
10.2174/1568006053005056
P577
2005-02-01T00:00:00Z