The role of alpha-synuclein in neurodegenerative diseases.
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Proteomics analysis identifies phosphorylation-dependent alpha-synuclein protein interactionsα-Synuclein negatively regulates protein kinase Cδ expression to suppress apoptosis in dopaminergic neurons by reducing p300 histone acetyltransferase activityExcess α-synuclein worsens disease in mice lacking ubiquitin carboxy-terminal hydrolase L1Sensitivity of secondary structure propensities to sequence differences between alpha- and gamma-synuclein: implications for fibrillationThe abolishment of anesthesia-induced cognitive impairment by timely protection of mitochondria in the developing rat brain: the importance of free oxygen radicals and mitochondrial integrityAnesthesia-induced developmental neurodegeneration: the role of neuronal organelles.Modelling Ser129 phosphorylation inhibits membrane binding of pore-forming alpha-synuclein oligomersMechanisms of hybrid oligomer formation in the pathogenesis of combined Alzheimer's and Parkinson's diseases.Decreased Expression of α-Synuclein, Nogo-A and UCH-L1 in Patients with Schizophrenia: A Preliminary Serum Study.DJ-1 deficient mice demonstrate similar vulnerability to pathogenic Ala53Thr human alpha-syn toxicity.α-synuclein reactive antibodies as diagnostic biomarkers in blood sera of Parkinson's disease patients.Lewy bodies.Neuropathology, biochemistry, and biophysics of alpha-synuclein aggregation.Alpha-synuclein in peripheral tissues and body fluids as a biomarker for Parkinson's disease - a systematic review.Improved immunodetection of endogenous α-synucleinProteomics in neurodegenerative diseases: Methods for obtaining a closer look at the neuronal proteome.Effect of lysosomal and ubiquitin-proteasome system dysfunction on the abnormal aggregation of α-synuclein in PC12 cells.Macrophages associated with the intrinsic and extrinsic autonomic innervation of the rat gastrointestinal tract.Catabolic insufficiency and aging.Alpha-synuclein pathology and axonal degeneration of the peripheral motor nerves innervating pharyngeal muscles in Parkinson diseaseMitochondrial import and accumulation of alpha-synuclein impair complex I in human dopaminergic neuronal cultures and Parkinson disease brain.Role of Ser129 phosphorylation of α-synuclein in melanoma cellsInteractions between metals and alpha-synuclein--function or artefact?Multiple system atrophy: alpha-synuclein and neuronal degeneration.Alpha-synuclein-immunopositive myenteric neurons and vagal preganglionic terminals: autonomic pathway implicated in Parkinson's disease?Lysosomes in iron metabolism, ageing and apoptosis.Physiological and pathological role of alpha-synuclein in Parkinson's disease through iron mediated oxidative stress; the role of a putative iron-responsive elementImmunological features of alpha-synuclein in Parkinson's disease.Alpha-synuclein immunopositive aggregates in the myenteric plexus of the aging Fischer 344 rat.Molecular mechanism of active zone organization at vertebrate neuromuscular junctions.Mitochondrial trafficking of APP and alpha synuclein: Relevance to mitochondrial dysfunction in Alzheimer's and Parkinson's diseases.Mitochondrial turnover and aging of long-lived postmitotic cells: the mitochondrial-lysosomal axis theory of aging.Role of α-synuclein penetration into the membrane in the mechanisms of oligomer pore formation.Computational approaches to understanding protein aggregation in neurodegeneration.Vulnerability of mesostriatal dopaminergic neurons in Parkinson's diseaseRifampicin and Parkinson's disease.Targeting the chameleon: a focused look at α-synuclein and its roles in neurodegeneration.Intrinsic disorder in proteins: a challenge for (un)structural biology met by ion mobility-mass spectrometry.Prolyl oligopeptidase enhances α-synuclein dimerization via direct protein-protein interactionα-Synuclein-induced mitochondrial dysfunction in isolated preparation and intact cells: implications in the pathogenesis of Parkinson's disease.
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P2860
The role of alpha-synuclein in neurodegenerative diseases.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
The role of alpha-synuclein in neurodegenerative diseases.
@ast
The role of alpha-synuclein in neurodegenerative diseases.
@en
type
label
The role of alpha-synuclein in neurodegenerative diseases.
@ast
The role of alpha-synuclein in neurodegenerative diseases.
@en
prefLabel
The role of alpha-synuclein in neurodegenerative diseases.
@ast
The role of alpha-synuclein in neurodegenerative diseases.
@en
P1476
The role of alpha-synuclein in neurodegenerative diseases.
@en
P2093
M Catherine Bennett
P304
P356
10.1016/J.PHARMTHERA.2004.10.010
P577
2004-12-08T00:00:00Z