Fibroblast growth factor 21 limits lipotoxicity by promoting hepatic fatty acid activation in mice on methionine and choline-deficient diets - Wikidata - wikimedia - TriplyDB

Fibroblast growth factor 21 limits lipotoxicity by promoting hepatic fatty acid activation in mice on methionine and choline-deficient diets

Fibroblast growth factor 21 limits lipotoxicity by promoting hepatic fatty acid activation in mice on methionine and choline-deficient diets

http://www.wikidata.org/entity/Q36061647

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Treatment of patients with type 2 diabetes and non-alcoholic fatty liver disease: current approaches and future directions Research Perspectives on the Regulation and Physiological Functions of FGF21 and its Association with NAFLD Fibroblast Growth Factor 21 (FGF21) Protects against High Fat Diet Induced Inflammation and Islet Hyperplasia in Pancreas Fibroblast Growth Factor 21 Analogs for Treating Metabolic Disorders.Metabolic Adaptation in Obesity and Type II Diabetes: Myokines, Adipokines and Hepatokines Regulation of Hepatic Stellate Cells and Fibrogenesis by Fibroblast Growth Factors β-Klotho deficiency protects against obesity through a crosstalk between liver, microbiota, and brown adipose tissue.Complementary Role of Fibroblast Growth Factor 21 and Cytokeratin 18 in Monitoring the Different Stages of Nonalcoholic Fatty Liver Disease.Fructose ingestion acutely stimulates circulating FGF21 levels in humans.Role of fibroblast growth factor 21 in the early stage of NASH induced by methionine- and choline-deficient diet Forced Hepatic Overexpression of CEACAM1 Curtails Diet-Induced Insulin Resistance Hepatocyte X-box binding protein 1 deficiency increases liver injury in mice fed a high-fat/sugar diet.Fibroblast Activation Protein Cleaves and Inactivates Fibroblast Growth Factor 21 Fibroblast Growth Factor 21 Mediates Glycemic Regulation by Hepatic JNK Role of Serum Biomarkers in Early Detection of Non-Alcoholic Steatohepatitis and Fibrosis in West Virginian Children.Fibroblast growth factor 21 and exercise-induced hepatic mitochondrial adaptations.Hyperlipidemia and hepatitis in liver-specific CREB3L3 knockout mice generated using a one-step CRISPR/Cas9 system Single ingestion of soy β-conglycinin induces increased postprandial circulating FGF21 levels exerting beneficial health effects.A liver stress-endocrine nexus promotes metabolic integrity during dietary protein dilution.A critical role for ChREBP-mediated FGF21 secretion in hepatic fructose metabolism.PPARs and Mitochondrial Metabolism: From NAFLD to HCC.The Effect of Sitagliptin on Lipid Metabolism of Fatty Liver Mice and Related Mechanisms.Targeting fibroblast growth factor 19 in liver disease: a potential biomarker and therapeutic target.Pharmacotherapy for Nonalcoholic Fatty Liver Disease.Effect of circulating glucagon and free fatty acids on hepatic FGF21 production in dairy cows.The emerging role of fibroblast growth factor 21 in diabetic nephropathy.Fibroblast growth factor 21: a regulator of metabolic disease and health span.Targeting adipose tissue in the treatment of obesity-associated diabetes.Fibroblast growth factor 21 night watch: advances and uncertainties in the field.Hepatic CEACAM1 Over-Expression Protects Against Diet-Induced Fibrosis and Inflammation in White Adipose Tissue.Fibroblast growth factor 21 improves hepatic insulin sensitivity by inhibiting mammalian target of rapamycin complex 1 in mice.Activation of aryl hydrocarbon receptor dissociates fatty liver from insulin resistance by inducing fibroblast growth factor 21.Liver PPARα is crucial for whole-body fatty acid homeostasis and is protective against NAFLD.Fibroblast growth factor 21 (FGF21) is robustly induced by ethanol and has a protective role in ethanol associated liver injury.Induction of fibroblast growth factor 21 does not require activation of the hepatic X-box binding protein 1 in mice.Dual role of protein tyrosine phosphatase 1B in the progression and reversion of non-alcoholic steatohepatitis.Fibroblast growth factor 21 decreases after liver fat reduction via growth hormone augmentation.Circulating fibroblast growth factor 21 in patients with liver cirrhosis.LY2405319, an analog of fibroblast growth factor 21 ameliorates α-smooth muscle actin production through inhibition of the succinate-G-protein couple receptor 91 (GPR91) pathway in mice.A novel glucagon-like peptide 1/glucagon receptor dual agonist improves steatohepatitis and liver regeneration in mice.

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Fibroblast growth factor 21 limits lipotoxicity by promoting hepatic fatty acid activation in mice on methionine and choline-deficient diets

http://www.wikidata.org/entity/Q36061647

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Fibroblast growth factor 21 li ...... ne and choline-deficient diets

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J.GASTRO.2014.07.044

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Gastroenterology

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Fibroblast growth factor 21 li ...... ne and choline-deficient diets

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Alexei Kharitonenkov

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Detlef Schuppan

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Ffolliott M Fisher

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Imad A Nasser

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Jeffrey S Flier

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Jeremy C Cunniff

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Patricia C Chui

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Thomas Lundasen

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Yury Popov

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P2860

FGF-21 as a novel metabolic regulator.

Obesity is a fibroblast growth factor 21 (FGF21)-resistant state

FGF21 induces PGC-1alpha and regulates carbohydrate and fatty acid metabolism during the adaptive starvation response

Acyl-coenzyme A synthetases in metabolic control

Design and validation of a histological scoring system for nonalcoholic fatty liver disease

Prevalence of hepatic steatosis in an urban population in the United States: impact of ethnicity

Hepatic fibroblast growth factor 21 is regulated by PPARalpha and is a key mediator of hepatic lipid metabolism in ketotic states

Endocrine regulation of the fasting response by PPARalpha-mediated induction of fibroblast growth factor 21

Mitochondrial abnormalities in non-alcoholic steatohepatitis.

Acyl-CoA synthesis, lipid metabolism and lipotoxicity.

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1073-83.e6

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10.1053/J.GASTRO.2014.07.044

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5

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Eleftheria Maratos-Flier

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2014-07-30T00:00:00Z

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264432295

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