E3 ubiquitin ligase Cbl-b regulates Pten via Nedd4 in T cells independently of its ubiquitin ligase activity - Wikidata - wikimedia - TriplyDB

E3 ubiquitin ligase Cbl-b regulates Pten via Nedd4 in T cells independently of its ubiquitin ligase activity

E3 ubiquitin ligase Cbl-b regulates Pten via Nedd4 in T cells independently of its ubiquitin ligase activity

http://www.wikidata.org/entity/Q36070980

about

Ubiquitylation as a Rheostat for TCR Signaling: From Targeted Approaches Toward Global Profiling PTEN is a protein tyrosine phosphatase for IRS1 E3 Ubiquitin Ligase NEDD4 Promotes Influenza Virus Infection by Decreasing Levels of the Antiviral Protein IFITM3 Usp12 stabilizes the T-cell receptor complex at the cell surface during signaling Regulation of the PI3K pathway through a p85α monomer-homodimer equilibrium TCR-induced, PKC-θ-mediated NF-κB activation is regulated by a caspase-8-caspase-9-caspase-3 cascade.E3 ubiquitin ligase Cbl-b in innate and adaptive immunity.Ubiquitin E3 ligase Nedd4-1 acts as a downstream target of PI3K/PTEN-mTORC1 signaling to promote neurite growth.E3 Ubiquitin Ligase Cbl-b Regulates Thymic-Derived CD4+CD25+ Regulatory T Cell Development by Targeting Foxp3 for Ubiquitination Nedd4 haploinsufficient mice display moderate insulin resistance, enhanced lipolysis, and protection against high-fat diet-induced obesity.Cbl-b: Roles in T Cell Tolerance, Proallergic T Cell Development, and Cancer Immunity.Protein Tyrosine Phosphatase SHP-1 Modulates T Cell Responses by Controlling Cbl-b Degradation Tumor suppressor TSC1 is critical for T-cell anergy PTEN and NEDD4 in Human Breast Carcinoma.MicroRNAs and Glucocorticoid-Induced Apoptosis in Lymphoid Malignancies The role of E3 ubiquitin ligase Cbl proteins in interleukin-2-induced Jurkat T-cell activation.T cell activation threshold regulated by E3 ubiquitin ligase Cbl-b determines fate of inducible regulatory T cells.Targeting CBLB as a potential therapeutic approach for disseminated candidiasis.E3 ubiquitin ligase Cbl-b suppresses proallergic T cell development and allergic airway inflammation PD-1 coinhibitory signals: the link between pathogenesis and protection.Recent progress in omics-driven analysis of MS to unravel pathological mechanisms.Role of inositol poly-phosphatases and their targets in T cell biology.Oncoprotein stabilization in brain tumors.Cell regulation by phosphotyrosine-targeted ubiquitin ligases.Modulation of Immune Cell Functions by the E3 Ligase Cbl-b.Modulating Host Signaling Pathways to Promote Resistance to Infection by Candida albicans.Glycogen Synthase Kinase-3 Modulates Cbl-b and Constrains T Cell Activation.Lys63-polyubiquitination by the E3 ligase casitas B-lineage lymphoma-b (Cbl-b) modulates peripheral regulatory T cell tolerance in patients with systemic lupus erythematosus.Immune Regulation by Ubiquitin Tagging as Checkpoint Code.

P2860

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P2860

E3 ubiquitin ligase Cbl-b regulates Pten via Nedd4 in T cells independently of its ubiquitin ligase activity

http://www.wikidata.org/entity/Q36070980

description

2012 nî lūn-bûn

@nan

2012年の論文

@ja

2012年論文

@yue

2012年論文

@zh-hant

2012年論文

@zh-hk

2012年論文

@zh-mo

2012年論文

@zh-tw

2012年论文

@wuu

2012年论文

@zh

2012年论文

@zh-cn

name

E3 ubiquitin ligase Cbl-b regu ...... its ubiquitin ligase activity

@ast

E3 ubiquitin ligase Cbl-b regu ...... its ubiquitin ligase activity

@en

type

label

E3 ubiquitin ligase Cbl-b regu ...... its ubiquitin ligase activity

@ast

E3 ubiquitin ligase Cbl-b regu ...... its ubiquitin ligase activity

@en

prefLabel

E3 ubiquitin ligase Cbl-b regu ...... its ubiquitin ligase activity

@ast

E3 ubiquitin ligase Cbl-b regu ...... its ubiquitin ligase activity

@en

P1433

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P356

J.CELREP.2012.04.008

P1433

P1476

E3 ubiquitin ligase Cbl-b regu ...... its ubiquitin ligase activity

@en

P2093

Guilin Qiao

http://www.w3.org/2001/XMLSchema#string

Haiyan Ying

http://www.w3.org/2001/XMLSchema#string

Hui Guo

http://www.w3.org/2001/XMLSchema#string

Jian Zhang

http://www.w3.org/2001/XMLSchema#string

Lifen Yang

http://www.w3.org/2001/XMLSchema#string

Stanley Lipkowitz

http://www.w3.org/2001/XMLSchema#string

Wallace Y Langdon

http://www.w3.org/2001/XMLSchema#string

Yanran Liang

http://www.w3.org/2001/XMLSchema#string

Yixia Zhao

http://www.w3.org/2001/XMLSchema#string

Zhenping Li

http://www.w3.org/2001/XMLSchema#string

P2860

NEDD4-1 is a proto-oncogenic ubiquitin ligase for PTEN

Ubiquitination regulates PTEN nuclear import and tumor suppression

PI3K delta and PI3K gamma: partners in crime in inflammation in rheumatoid arthritis and beyond?

Calcineurin imposes T cell unresponsiveness through targeted proteolysis of signaling proteins

Rak functions as a tumor suppressor by regulating PTEN protein stability and function

Selective CD28pYMNM mutations implicate phosphatidylinositol 3-kinase in CD86-CD28-mediated costimulation

Binding of phosphatidylinositol-3-OH kinase to CD28 is required for T-cell signalling

Nedd4 augments the adaptive immune response by promoting ubiquitin-mediated degradation of Cbl-b in activated T cells

Nedd4 controls animal growth by regulating IGF-1 signaling

The ubiquitin ligase Nedd4-1 is dispensable for the regulation of PTEN stability and localization

P304

472-482

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P31

scholarly article

P356

10.1016/J.CELREP.2012.04.008

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P433

5

http://www.w3.org/2001/XMLSchema#string

P478

1

http://www.w3.org/2001/XMLSchema#string

P50

Josef M Penninger

P577

2012-05-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

228324373

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P698

22763434

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P932

3387815

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