Structure-Activity Study of Bioisosteric Trifluoromethyl and Pentafluorosulfanyl Indole Inhibitors of the AAA ATPase p97.

Structure-Activity Study of Bioisosteric Trifluoromethyl and Pentafluorosulfanyl Indole Inhibitors of the AAA ATPase p97.

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http://www.wikidata.org/entity/Q36367307
Targeting p97 to Disrupt Protein Homeostasis in CancerOptimization of pyrazole-containing 1,2,4-triazolo-[3,4-b]thiadiazines, a new class of STAT3 pathway inhibitorsA Mighty "Protein Extractor" of the Cell: Structure and Function of the p97/CDC48 ATPase.Allosteric Indole Amide Inhibitors of p97: Identification of a Novel Probe of the Ubiquitin Pathway.Application of the Pentafluorosulfanyl Group as a Bioisosteric Replacement.A threonine turnstile defines a dynamic amphiphilic binding motif in the AAA ATPase p97 allosteric binding site.The AAA+ ATPase p97, a cellular multitool.VCP inhibitors induce endoplasmic reticulum stress, cause cell cycle arrest, trigger caspase-mediated cell death and synergistically kill ovarian cancer cells in combination with Salubrinal.Ni/Ir-Catalyzed Photoredox Decarboxylative Coupling of S-Substituted Thiolactic Acids with Heteroaryl Bromides: Short Synthesis of Sulfoxaflor and Its SF5 Analog.Silver-induced self-immolative Cl-F exchange fluorination of arylsulfur chlorotetrafluorides: synthesis of arylsulfur pentafluorides.Synthesis and Evaluation of Potent KCNQ2/3-Specific Channel Activators.Dichlorotrifluoromethoxyacetic Acid: Preparation and Reactivity.Racemic and enantioselective metal-catalyzed synthesis of SF5-containing diarylmethanols.Optimization of Phenyl Indole Inhibitors of the AAA+ ATPase p97
P2860

Structure-Activity Study of Bioisosteric Trifluoromethyl and Pentafluorosulfanyl Indole Inhibitors of the AAA ATPase p97.

Item
http://www.wikidata.org/entity/Q36367307
description
2015 nî lūn-bûn
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name
Structure-Activity Study of Bi ...... ibitors of the AAA ATPase p97.
@ast
Structure-Activity Study of Bi ...... ibitors of the AAA ATPase p97.
@en
type
label
Structure-Activity Study of Bi ...... ibitors of the AAA ATPase p97.
@ast
Structure-Activity Study of Bi ...... ibitors of the AAA ATPase p97.
@en
prefLabel
Structure-Activity Study of Bi ...... ibitors of the AAA ATPase p97.
@ast
Structure-Activity Study of Bi ...... ibitors of the AAA ATPase p97.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P698
P932
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P1433
P1476
Structure-Activity Study of Bi ...... ibitors of the AAA ATPase p97.
@en
P2093
P2860
P304
P31
P356
10.1021/ACSMEDCHEMLETT.5B00364
P433
P478
P50
P577
P698
P932