Cholinergic modulation of locomotion and striatal dopamine release is mediated by alpha6alpha4* nicotinic acetylcholine receptors. - Wikidata - wikimedia - TriplyDB

Cholinergic modulation of locomotion and striatal dopamine release is mediated by alpha6alpha4* nicotinic acetylcholine receptors.

Cholinergic modulation of locomotion and striatal dopamine release is mediated by alpha6alpha4* nicotinic acetylcholine receptors.

http://www.wikidata.org/entity/Q36079677

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Crucial roles of the CHRNB3-CHRNA6 gene cluster on chromosome 8 in nicotine dependence: update and subjects for future research Molecular mechanisms underlying behaviors related to nicotine addiction Preclinical evidence that activation of mesolimbic alpha 6 subunit containing nicotinic acetylcholine receptors supports nicotine addiction phenotype Dopaminergic and cholinergic learning mechanisms in nicotine addiction Efficient expression of functional (α6β2)2β3 AChRs in Xenopus oocytes from free subunits using slightly modified α6 subunits Roles for N-terminal extracellular domains of nicotinic acetylcholine receptor (nAChR) β3 subunits in enhanced functional expression of mouse α6β2β3- and α6β4β3-nAChRs.Analysis of rare variations reveals roles of amino acid residues in the N-terminal extracellular domain of nicotinic acetylcholine receptor (nAChR) alpha6 subunit in the functional expression of human alpha6*-nAChRs.How can we use our knowledge of alcohol-tobacco interactions to reduce alcohol use?Insights into the neurobiology of the nicotinic cholinergic system and nicotine addiction from mice expressing nicotinic receptors harboring gain-of-function mutations Elimination of the vesicular acetylcholine transporter in the striatum reveals regulation of behaviour by cholinergic-glutamatergic co-transmission.Progress and challenges in the study of α6-containing nicotinic acetylcholine receptors.Chronic administration of cholesterol oximes in mice increases transcription of cytoprotective genes and improves transcriptome alterations induced by alpha-synuclein overexpression in nigrostriatal dopaminergic neurons.Cocaine inhibition of nicotinic acetylcholine receptors influences dopamine release.Reward, addiction, withdrawal to nicotine.Acute ethanol inhibits dopamine release in the nucleus accumbens via α6 nicotinic acetylcholine receptors Nicotinic receptor antagonists as treatments for nicotine abuse.Expression of functional human α6β2β3* acetylcholine receptors in Xenopus laevis oocytes achieved through subunit chimeras and concatamers.Neurophysiology of Nicotine Addiction Distinct contributions of nicotinic acetylcholine receptor subunit alpha4 and subunit alpha6 to the reinforcing effects of nicotine.The necessity of α4* nicotinic receptors in nicotine-driven behaviors: dissociation between reinforcing and motor effects of nicotine.Effects of tobacco smoke constituents, anabasine and anatabine, on memory and attention in female rats.Nicotine and ethanol cooperate to enhance ventral tegmental area AMPA receptor function via α6-containing nicotinic receptors Nicotinic receptor subtype-selective circuit patterns in the subthalamic nucleus.Characterizing functional α6β2 nicotinic acetylcholine receptors in vitro: mutant β2 subunits improve membrane expression, and fluorescent proteins reveal responsive cells.α6β2* and α4β2* nicotinic acetylcholine receptors as drug targets for Parkinson's disease.Evidence for a role for α6(∗) nAChRs in l-dopa-induced dyskinesias using Parkinsonian α6(∗) nAChR gain-of-function mice Nicotinic acetylcholine receptors containing α6 subunits contribute to alcohol reward-related behaviours.Anxiolytic-like and anxiogenic-like effects of nicotine are regulated via diverse action at β2*nicotinic acetylcholine receptors Nicotinic cholinergic mechanisms causing elevated dopamine release and abnormal locomotor behavior.Differential roles of α6β2* and α4β2* neuronal nicotinic receptors in nicotine- and cocaine-conditioned reward in mice.Role of α6 nicotinic receptors in CNS dopaminergic function: relevance to addiction and neurological disorders.Striatal pathology underlies prion infection-mediated hyperactivity in mice.Nicotinic acetylcholine receptors in dorsal root ganglion neurons include the α6β4* subtype.Modulation of gain-of-function α6*-nicotinic acetylcholine receptor by β3 subunits.Nicotinic receptor contributions to smoking: insights from human studies and animal models α6-Containing nicotinic acetylcholine receptors in midbrain dopamine neurons are poised to govern dopamine-mediated behaviors and synaptic plasticity Sensing Positive versus Negative Reward Signals through Adenylyl Cyclase-Coupled GPCRs in Direct and Indirect Pathway Striatal Medium Spiny Neurons.α6* nicotinic acetylcholine receptor expression and function in a visual salience circuit.Nicotine Dependence Reveals Distinct Responses from Neurons and Their Resident Nicotinic Receptors in Medial Habenula.Local application of drugs to study nicotinic acetylcholine receptor function in mouse brain slices.

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Cholinergic modulation of locomotion and striatal dopamine release is mediated by alpha6alpha4* nicotinic acetylcholine receptors.

http://www.wikidata.org/entity/Q36079677

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2010 nî lūn-bûn

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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2010年论文

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2010年论文

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Cholinergic modulation of loco ...... tinic acetylcholine receptors.

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Cholinergic modulation of loco ...... tinic acetylcholine receptors.

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Cholinergic modulation of loco ...... tinic acetylcholine receptors.

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Cholinergic modulation of loco ...... tinic acetylcholine receptors.

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Cholinergic modulation of loco ...... tinic acetylcholine receptors.

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Cholinergic modulation of loco ...... tinic acetylcholine receptors.

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JNEUROSCI.2056-10.2010

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Journal of Neuroscience

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Cholinergic modulation of loco ...... otinic acetylcholine receptors

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Andrew D Steele

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J Michael McIntosh

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Michael J Marks

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Natalie E Patzlaff

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Ryan M Drenan

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Sharon R Grady

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Sheri McKinney

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P2860

Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter

In vivo activation of midbrain dopamine neurons via sensitized, high-affinity alpha 6 nicotinic acetylcholine receptors

Dopamine reward circuitry: two projection systems from the ventral midbrain to the nucleus accumbens-olfactory tubercle complex.

A new alpha-conotoxin which targets alpha3beta2 nicotinic acetylcholine receptors

Varenicline: an alpha4beta2 nicotinic receptor partial agonist for smoking cessation

Subunit composition of functional nicotinic receptors in dopaminergic neurons investigated with knock-out mice

Phenotypic characterization of an alpha 4 neuronal nicotinic acetylcholine receptor subunit knock-out mouse

Altered dopamine release and uptake kinetics in mice lacking D2 receptors

Molecular and physiological diversity of nicotinic acetylcholine receptors in the midbrain dopaminergic nuclei

Distribution and pharmacology of alpha 6-containing nicotinic acetylcholine receptors analyzed with mutant mice

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10.1523/JNEUROSCI.2056-10.2010

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29

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2010-07-01T00:00:00Z

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20660270

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corpus striatum

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3390922

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