Amplification of the MDM2 gene in human breast cancer and its association with MDM2 and p53 protein status.
about
p53-dependent ceramide response to genotoxic stressDrugging the undruggables: exploring the ubiquitin system for drug developmentAlterations of the Notch pathway in lung cancer.P53, apoptosis, and breast cancerAltered expression of p53 and its regulated proteins in phyllodes tumours of the breast.Fulvestrant treatment alters MDM2 protein turnover and sensitivity of human breast carcinoma cells to chemotherapeutic drugsAmplification and overexpression of mdm2 gene in ependymomas.Driver mutations in TP53 are ubiquitous in high grade serous carcinoma of the ovary.The MDM2 gene amplification databaseMDM2 promotes cell motility and invasiveness by regulating E-cadherin degradation.Cell type-specific inhibition of p53-mediated apoptosis by mdm2.DNA amplifications at 20q13 and MDM2 define distinct subsets of evolved breast and ovarian tumours.Mdm2 in growth signaling and cancer.OVA12 promotes tumor growth by regulating p53 expression in human cancer cells.MDM2 gene amplification and expression in non-small-cell lung cancer: immunohistochemical expression of its protein is a favourable prognostic marker in patients without p53 protein accumulation.In squamous cell carcinoma of the vulva, overexpression of p53 is a late event and neither p53 nor mdm2 expression is a useful marker to predict lymph node metastasesEstrogen receptor alpha (ERα/ESR1) mediates the p53-independent overexpression of MDM4/MDMX and MDM2 in human breast cancer.Prevalence and co-occurrence of actionable genomic alterations in high-grade bladder cancer.Pleomorphic lobular carcinoma of the breast: molecular pathology and clinical impact.SHARPIN Facilitates p53 Degradation in Breast Cancer Cells.Amplification of Mdmx and overexpression of MDM2 contribute to mammary carcinogenesis by substituting for p53 mutations.MDM2 protein expression is a negative prognostic marker in breast carcinoma.A comparison of cell cycle markers in well-differentiated lobular and ductal carcinomas.Altered expression of mdm-2 and its association with p53 protein status, tumor-cell-proliferation rate and prognosis in cervical neoplasia.The Role of MDM2 Amplification and Overexpression in Tumorigenesis.The overexpression of SOX2 affects the migration of human teratocarcinoma cell line NT2/D1.The role of genes co-amplified with nicastrin in breast invasive carcinoma.Progesterone inhibition of MDM2 p90 protein in MCF-7 human breast cancer cell line is dependent on p53 levels.Estradiol stabilizes p53 protein in breast cancer cell line, MCF-7.Interaction between p53 codon 72 and MDM2 309T>G polymorphisms and the risk of hepatocellular carcinoma.The mdm2 proto-oncogene.Mdm-2: "big brother" of p53.Interferon-inducible protein IFIXalpha1 functions as a negative regulator of HDM2.p53 alterations and their relationship to SDHD mutations in parasympathetic paragangliomas.Chemosensitization and radiosensitization of human cancer by antisense anti-MDM2 oligonucleotides: in vitro and in vivo activities and mechanisms.Increased expression of MDM2, cyclin D1, and p27Kip1 in carcinogen-induced rat mammary tumors.Molecular profiling pleomorphic lobular carcinomas of the breast: evidence for a common molecular genetic pathway with classic lobular carcinomas.The biological, clinical and prognostic implications of p53 transcriptional pathways in breast cancers.Alternatively spliced MDM2 transcripts in human breast cancer in relation to tumor necrosis and lymph node involvement.Genetic alterations of the p14ARF -hdm2-p53 regulatory pathway in breast carcinoma.
P2860
Q24564604-1E9250DC-72DC-4F33-8968-DBFABC60D0C6Q26752823-2B459B4E-6893-4C4B-9454-25B0798DEB88Q27851544-B73A8A55-DB24-4AA4-8A88-69ABD02E41C1Q28611354-FD44E6F3-AED5-4A0A-A11B-C3A25CC11608Q33179097-4CA437B5-DA43-4C4D-A30C-2FBD01061016Q33880170-E125F2FD-70C1-4C76-89D6-1954335B41D9Q33902910-7470629E-CA7B-4AD1-BC37-23ECE849AFD3Q34103978-6C7E55C8-6E49-43DA-A1EC-D5F56B6D48C8Q34672224-BD9F920B-74A3-405C-B697-1AF704D4803AQ35071303-C92DA62B-5621-494B-93BF-1674E8F9CA10Q35847043-0554D0FF-BA66-45F0-857B-72B83786752EQ36136448-AE7AE981-397F-4B2A-8375-449F98C0ECF6Q36294472-4337D6A7-08CF-43C5-AFC8-C70A4A2D042DQ36376797-14A8A858-A624-4EA3-9F3A-E3D96D4EC091Q36431703-12216AC3-8A5B-4A5A-93B7-72EA78D0E3D7Q36620156-63DEF099-F496-4335-8487-2E9DB4FA7AABQ37085951-928201AC-9C17-4397-877D-0E8954A772BFQ37122307-2592CD72-0602-485E-9855-7864B4EA0701Q37414366-EB5B147F-6962-48D2-A911-A7DE6B59B1C4Q37569188-52FDB076-AD15-42D5-931F-73CB17DC3A94Q37703117-D6D9B8B8-1018-43E4-ABAD-922986D67CA9Q38440364-5C7303B3-7EE2-46C4-B33B-20792D608703Q38464166-E7948593-783E-44EF-B27D-B2C5E9A2AB2AQ38473896-E89F8B69-C8BD-43CF-BE67-881290BDAE0FQ38837916-123AA5A5-41FA-47CC-A892-8C7D92DE75B2Q38901084-926CB5D5-762E-4F07-BDD3-ABDAC81FE564Q39043428-891A9A63-454D-44CD-BB2B-02BB58B36FCCQ40476066-0680243A-C81E-4C62-8416-518650D9FF91Q40652110-9F9F5B4A-905B-4339-96E3-E9169CFDB88EQ40947646-6E3D2037-240F-4BDA-9250-EDE7DB7F8D72Q41100486-F773CF20-8B7F-4FCA-931D-AC84399F17D9Q41370313-4F5DD5B3-80B7-4AE6-ADC4-EB540C06F725Q41412965-D5377A01-784A-4DDC-9181-99FDEE8E4280Q44588662-1BB120A8-93F7-494D-9307-489CDF53FDEEQ44748720-40A6D875-2016-44D6-931E-BC019814E2DBQ46448681-A6AC4D56-FF98-415D-AB75-20088A03BB5BQ46600448-C8057782-57BF-41CE-B8E1-735F5680B001Q50571194-D16F9A6E-9749-4CC7-8A67-306028352678Q52541714-D60390A4-B599-4B99-9AB9-8047CA1F9DDAQ53399243-D59EC49A-72CD-4B39-B250-D9F5E31FDD47
P2860
Amplification of the MDM2 gene in human breast cancer and its association with MDM2 and p53 protein status.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
Amplification of the MDM2 gene ...... h MDM2 and p53 protein status.
@ast
Amplification of the MDM2 gene ...... h MDM2 and p53 protein status.
@en
type
label
Amplification of the MDM2 gene ...... h MDM2 and p53 protein status.
@ast
Amplification of the MDM2 gene ...... h MDM2 and p53 protein status.
@en
prefLabel
Amplification of the MDM2 gene ...... h MDM2 and p53 protein status.
@ast
Amplification of the MDM2 gene ...... h MDM2 and p53 protein status.
@en
P2093
P2860
P356
P1476
Amplification of the MDM2 gene ...... th MDM2 and p53 protein status
@en
P2093
P2860
P2888
P304
P356
10.1038/BJC.1995.189
P407
P50
P577
1995-05-01T00:00:00Z