Anti-metastatic therapy by urinary trypsin inhibitor in combination with an anti-cancer agent
about
The protease inhibitor bikunin, a novel anti-metastatic agentImmunohistochemical distribution of inter-alpha-trypsin inhibitor chains in normal and malignant human lung tissueKunitz-type protease inhibitor bikunin disrupts phorbol ester-induced oligomerization of CD44 variant isoforms containing epitope v9 and subsequently suppresses expression of urokinase-type plasminogen activator in human chondrosarcoma cellsBikunin inhibits lipopolysaccharide-induced tumor necrosis factor alpha induction in macrophagesEffects of ulinastatin and docataxel on breast tumor growth and expression of IL-6, IL-8, and TNF-α.Hyaluronidase activity in gynaecological cancer tissues with different metastatic forms.Two legume defense proteins suppress the mobility of nasopharyngeal carcinoma cells.PDGF-D/PDGF-ββ receptor-regulated chemotaxis of malignant mesothelioma cells.Effects of ulinastatin and cyclophosphamide on the growth of xenograft breast cancer and expression of CXC chemokine receptor 4 and matrix metalloproteinase-9 in cancers.Suppression of urokinase expression and invasion by a soybean Kunitz trypsin inhibitor are mediated through inhibition of Src-dependent signaling pathways.Bikunin down-regulates heterodimerization between CD44 and growth factor receptors and subsequently suppresses agonist-mediated signaling.Transforming growth factor-beta1 produced by ovarian cancer cell line HRA stimulates attachment and invasion through an up-regulation of plasminogen activator inhibitor type-1 in human peritoneal mesothelial cells.A Kunitz-type protease inhibitor, bikunin, inhibits ovarian cancer cell invasion by blocking the calcium-dependent transforming growth factor-beta 1 signaling cascade.Characterization of binding properties of urinary trypsin inhibitor to cell-associated binding sites on human chondrosarcoma cell line HCS-2/8.Suppression of urokinase expression and invasiveness by urinary trypsin inhibitor is mediated through inhibition of protein kinase C- and MEK/ERK/c-Jun-dependent signaling pathways.Effects of combined in vivo treatment of transplantable solid mammary carcinoma in wistar rats using vitamin E and cysteine peptidase inhibitors from human placenta.Therapeutic efficacy of once-daily oral administration of a Kunitz-type protease inhibitor, bikunin, in a mouse model and in human cancer.Development of a method for urine bikunin/urinary trypsin inhibitor (UTI) quantitation and structural characterization: Application to type 1 and type 2 diabetes.Reduced bikunin gene expression as a factor of poor prognosis in ovarian carcinoma.Bikunin plus paclitaxel markedly reduces tumor burden and ascites in mouse model of ovarian cancer.The synergistic effect of propofol and ulinastatin suppressed the viability of the human lung adenocarcinoma epithelial A549 cell line
P2860
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P2860
Anti-metastatic therapy by urinary trypsin inhibitor in combination with an anti-cancer agent
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
Anti-metastatic therapy by uri ...... tion with an anti-cancer agent
@ast
Anti-metastatic therapy by uri ...... tion with an anti-cancer agent
@en
type
label
Anti-metastatic therapy by uri ...... tion with an anti-cancer agent
@ast
Anti-metastatic therapy by uri ...... tion with an anti-cancer agent
@en
prefLabel
Anti-metastatic therapy by uri ...... tion with an anti-cancer agent
@ast
Anti-metastatic therapy by uri ...... tion with an anti-cancer agent
@en
P2093
P2860
P356
P1476
Anti-metastatic therapy by uri ...... tion with an anti-cancer agent
@en
P2093
P2860
P2888
P304
P356
10.1038/BJC.1995.476
P407
P577
1995-11-01T00:00:00Z