Expression of a constitutively active erythropoietin receptor in primary hematopoietic progenitors abrogates erythropoietin dependence and enhances erythroid colony-forming unit, erythroid burst-forming unit, and granulocyte/macrophage progenitor gr
about
The prolactin receptor and severely truncated erythropoietin receptors support differentiation of erythroid progenitorsErythropoietin blockade inhibits the induction of tumor angiogenesis and progression.Abnormalities of cytokine receptor signalling contributing to diseases of red blood cell production.Characterization of purified intraembryonic hematopoietic stem cells as a tool to define their site of origin.Cooperation of Spi-1/PU.1 with an activated erythropoietin receptor inhibits apoptosis and Epo-dependent differentiation in primary erythroblasts and induces their Kit ligand-dependent proliferation.Large-scale production of red blood cells from stem cells: what are the technical challenges ahead?Expression of an activated erythropoietin or a colony-stimulating factor 1 receptor by pluripotent progenitors enhances colony formation but does not induce differentiationConstitutive activation of a variant of the env-mpl oncogene product by disulfide-linked homodimerization.Signaling by chimeric erythropoietin-TGF-beta receptors: homodimerization of the cytoplasmic domain of the type I TGF-beta receptor and heterodimerization with the type II receptor are both required for intracellular signal transduction.Control of hematopoietic differentiation: lack of specificity in signaling by cytokine receptors.High efficiency retroviral mediated gene transduction into single isolated immature and replatable CD34(3+) hematopoietic stem/progenitor cells from human umbilical cord blood.Enforced granulocyte/macrophage colony-stimulating factor signals do not support lymphopoiesis, but instruct lymphoid to myelomonocytic lineage conversion.Absence of cytokine receptor-dependent specificity in red blood cell differentiation in vivoHematopoietic growth factors, signaling and the chronic myeloproliferative disorders.A constitutively activated erythropoietin receptor stimulates proliferation and contributes to transformation of multipotent, committed nonerythroid and erythroid progenitor cells.Murine pluripotent hematopoietic progenitors constitutively expressing a normal erythropoietin receptor proliferate in response to erythropoietin without preferential erythroid cell differentiation.Oligomerization and scaffolding functions of the erythropoietin receptor cytoplasmic tail.BCR-ABL and v-SRC tyrosine kinase oncoproteins support normal erythroid development in erythropoietin receptor-deficient progenitor cells.Erythropoietin receptors that signal through Stat5 or Stat3 support fetal liver and adult erythropoiesis: lack of specificity of stat signals during red blood cell development.Dysregulated hematopoiesis and a progressive neurological disorder induced by expression of an activated form of the human common beta chain in transgenic mice.The erythropoietin receptor: molecular structure and hematopoietic signaling pathways.Activation and inhibition of erythropoietin receptor function: role of receptor dimerization.Erythropoietin receptor contributes to melanoma cell survival in vivo.Unpaired Extracellular Cysteine Mutations of CSF3R Mediate Gain or Loss of Function.Cell surface organization of the erythropoietin receptor complex differs depending on its mode of activation.JAK2 V617F stimulates proliferation of erythropoietin-dependent erythroid progenitors and delays their differentiation by activating Stat1 and other nonerythroid signaling pathways.
P2860
Q28238908-AED98E67-71AD-4A2B-97ED-CCDF706AAB43Q33288270-AD0B83F8-6BC5-4DB7-882B-F032E8E4D41DQ33708686-570F092F-A8F1-4C92-A798-213F7541E1CAQ33715031-AB7A1990-ECE9-4A7C-BA2B-E25CD740C4DBQ33887496-E21BD0BF-45C8-4960-B8DB-706D6FF0D9C2Q34658807-B34BAABE-F154-4143-8F5F-818E3A72FD5AQ35641376-6C1CD008-9E04-4A02-BFAB-7B3B515789F7Q35838599-EF06962F-9BED-417B-8299-8F2978FCC0DEQ35907449-63EA8F45-38CF-434B-9EFC-FDE7B4495E01Q36066346-86AAF90C-2F2D-407D-992F-CA9FD5A50F02Q36362618-408E3A84-FCBD-4D5D-891D-A7A25A49C6ABQ36370397-A4BF6E3D-5389-49B4-B748-EEB4CD3F77EEQ36505270-BC663C52-C782-4FCF-B22A-378E31A4CEA9Q36630747-8370A0A5-C824-4D04-A890-C211124477F5Q36649377-38BD57A7-89A7-409A-A24D-4B6C76993443Q36657459-B8384357-DE3D-4D06-A02D-46EB83703713Q36664597-22C752AE-FAC7-4F8D-AB0F-3E8F6E72A733Q36668207-74F93D94-AFEC-4318-9D7A-F6E49DBB1CBDQ36710195-FDFDF781-184F-4559-BE3C-2831EF5CC73FQ37388105-B66F61F3-6CD1-4116-BD55-9350622B92F0Q37838684-785F61F8-2C2A-47F4-AB3A-0340AC8A96EDQ38307491-4BC734D4-7B1D-4F03-992E-F6A00A01FDFFQ39486076-45DD62DA-0A67-444D-A56C-58A1EEFA05AFQ40144730-87682227-D7AC-4E56-8F72-8F83E61D3BE2Q41116762-DFD6213F-3920-4B6C-91AD-A08765410C00Q42679297-D0C1FC87-8008-42B3-A304-D5DF872122D1
P2860
Expression of a constitutively active erythropoietin receptor in primary hematopoietic progenitors abrogates erythropoietin dependence and enhances erythroid colony-forming unit, erythroid burst-forming unit, and granulocyte/macrophage progenitor gr
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
Expression of a constitutively ...... ocyte/macrophage progenitor gr
@ast
Expression of a constitutively ...... ocyte/macrophage progenitor gr
@en
type
label
Expression of a constitutively ...... ocyte/macrophage progenitor gr
@ast
Expression of a constitutively ...... ocyte/macrophage progenitor gr
@en
prefLabel
Expression of a constitutively ...... ocyte/macrophage progenitor gr
@ast
Expression of a constitutively ...... ocyte/macrophage progenitor gr
@en
P2093
P2860
P356
P1476
Expression of a constitutively ...... ocyte/macrophage progenitor gr
@en
P2093
A Hofbauer
G D Longmore
P2860
P304
P356
10.1073/PNAS.90.3.938
P407
P577
1993-02-01T00:00:00Z