The antidepressant sertraline provides a promising therapeutic option for neurotropic cryptococcal infections.
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Immunomodulatory effects mediated by serotoninAntifungal drug discovery: something old and something newIn Vitro Antifungal Activity of Sertraline and Synergistic Effects in Combination with Antifungal Drugs against Planktonic Forms and Biofilms of Clinical Trichosporon asahii IsolatesA novel mechanism of generating extracellular vesicles during apoptosis via a beads-on-a-string membrane structure.A repurposing approach identifies off-patent drugs with fungicidal cryptococcal activity, a common structural chemotype, and pharmacological properties relevant to the treatment of cryptococcosisThe Celecoxib Derivative AR-12 Has Broad-Spectrum Antifungal Activity In Vitro and Improves the Activity of Fluconazole in a Murine Model of Cryptococcosis.Rising to the challenge of multiple Cryptococcus species and the diseases they cause.Cryptococcal Meningitis: Diagnosis and Management Update.Development of protective inflammation and cell-mediated immunity against Cryptococcus neoformans after exposure to hyphal mutants.Increased Antifungal Drug Resistance in Clinical Isolates of Cryptococcus neoformans in Uganda.The lncRNA RZE1 Controls Cryptococcal Morphological Transition.The Anti-helminthic Compound Mebendazole Has Multiple Antifungal Effects against Cryptococcus neoformans.Congenic strains for genetic analysis of virulence traits in Cryptococcus gattiiCongenic strains of the filamentous form of Cryptococcus neoformans for studies of fungal morphogenesis and virulence.Efficacy of adjunctive sertraline for the treatment of HIV-associated cryptococcal meningitis: an open-label dose-ranging study.Cryptococcus: from environmental saprophyte to global pathogen.A complex game of hide and seek: the search for new antifungalsDiagnosis and Management of Cryptococcal Relapse.Modulation of Replicative Lifespan in Cryptococcus neoformans: Implications for Virulence.Combinatorial strategies for combating invasive fungal infections.Antifungal adjuvants: Preserving and extending the antifungal arsenalAntifungal drug development: challenges, unmet clinical needs, and new approaches.Newer patents in antimycotic therapy.Cryptococcal therapies and drug targets: the old, the new and the promising.Challenges in the development of novel anticryptococcal agents.Strategies in the discovery of novel antifungal scaffolds.Recent advances in AIDS-related cryptococcal meningitis treatment with an emphasis on resource limited settings.The antifungal pipeline: a reality check.Clinical evaluation of the antifungal effect of sertraline in the treatment of cryptococcal meningitis in HIV patients: a single Mexican center experience.Octahedral ruthenium (II) polypyridyl complexes as antimicrobial agents against mycobacterium.Subcellular Partitioning and Intramacrophage Selectivity of Antimicrobial Compounds against Mycobacterium tuberculosis.Activity of sertraline against Cryptococcus neoformans: in vitro and in vivo assays.Unraveling the biology of a fungal meningitis pathogen using chemical genetics.A Family of Secretory Proteins Is Associated with Different Morphotypes in Cryptococcus neoformans.Sertraline for HIV-associated cryptococcal meningitis - Authors' reply.Could repurposing existing drugs be an efficient protective method against microbial biologic threats?New Horizons in Antifungal Therapy.Virulence Factors as Targets for Anticryptococcal Therapy.Discovery of an Octahedral Silicon Complex as a Potent Antifungal Agent.Repurposing drugs to fast-track therapeutic agents for the treatment of cryptococcosis.
P2860
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P2860
The antidepressant sertraline provides a promising therapeutic option for neurotropic cryptococcal infections.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
The antidepressant sertraline ...... ropic cryptococcal infections.
@ast
The antidepressant sertraline ...... ropic cryptococcal infections.
@en
type
label
The antidepressant sertraline ...... ropic cryptococcal infections.
@ast
The antidepressant sertraline ...... ropic cryptococcal infections.
@en
prefLabel
The antidepressant sertraline ...... ropic cryptococcal infections.
@ast
The antidepressant sertraline ...... ropic cryptococcal infections.
@en
P2093
P2860
P356
P1476
The antidepressant sertraline ...... ropic cryptococcal infections.
@en
P2093
P2860
P304
P356
10.1128/AAC.00212-12
P407
P577
2012-04-16T00:00:00Z