Prazosin displays anticancer activity against human prostate cancers: targeting DNA and cell cycle
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The Role of α1-Adrenoceptor Antagonists in the Treatment of Prostate and Other CancersThe cytotoxicity of the α1-adrenoceptor antagonist prazosin is linked to an endocytotic mechanism equivalent to transport-P.Identification of novel p53 pathway activating small-molecule compounds reveals unexpected similarities with known therapeutic agentsNeoplasia: the second decade.The anti-hypertensive drug prazosin induces apoptosis in the medullary thyroid carcinoma cell line TT.Apoptosis induction by doxazosin and other quinazoline alpha1-adrenoceptor antagonists: a new mechanism for cancer treatment?The anti-hypertensive drug prazosin inhibits glioblastoma growth via the PKCδ-dependent inhibition of the AKT pathway.Bromodeoxyuridine inhibits cancer cell proliferation in vitro and in vivo.The prince and the pauper. A tale of anticancer targeted agents.The War on Cancer rages on.Insights into cardio-oncology: Polypharmacology of quinazoline-based α1-adrenoceptor antagonists.Relative cytotoxic potencies and cell death mechanisms of α1 -adrenoceptor antagonists in prostate cancer cell lines.Repurposing of phentolamine as a potential anticancer agent against human castration-resistant prostate cancer: A central role on microtubule stabilization and mitochondrial apoptosis pathway.Reduction of prostate cancer incidence by naftopidil, an α1 -adrenoceptor antagonist and transforming growth factor-β signaling inhibitor.Antitumor action of α(1)-adrenoceptor blockers on human bladder, prostate and renal cancer cells.Prazosin induces p53-mediated autophagic cell death in H9C2 cells.Novel quinazoline HMJ-30 induces U-2 OS human osteogenic sarcoma cell apoptosis through induction of oxidative stress and up-regulation of ATM/p53 signaling pathway.Mitochondrial DNA depletion induces radioresistance by suppressing G2 checkpoint activation in human pancreatic cancer cells.Neoplasia: An Anniversary of Progress.Anti-angiogenic effects and mechanism of prazosin.Release of intracellular calcium primes chronic myeloid leukaemia cells for tyrosine kinase inhibitor-induced apoptosis.Response of dogs with urinary tract obstructions secondary to prostatic carcinomas to the α-1 antagonist prazosin: TABLE 1
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P2860
Prazosin displays anticancer activity against human prostate cancers: targeting DNA and cell cycle
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Prazosin displays anticancer a ...... : targeting DNA and cell cycle
@ast
Prazosin displays anticancer a ...... : targeting DNA and cell cycle
@en
type
label
Prazosin displays anticancer a ...... : targeting DNA and cell cycle
@ast
Prazosin displays anticancer a ...... : targeting DNA and cell cycle
@en
prefLabel
Prazosin displays anticancer a ...... : targeting DNA and cell cycle
@ast
Prazosin displays anticancer a ...... : targeting DNA and cell cycle
@en
P2093
P2860
P356
P1433
P1476
Prazosin displays anticancer a ...... : targeting DNA and cell cycle
@en
P2093
Che-Jen Hsiao
Cho-Hwa Liao
Jih-Hwa Guh
Ping-Chiang Lyu
Shih-Chieh Chueh
Ssu-Chia Lin
Tsia-Kun Li
Tzu-Hsuan Chen
P2860
P304
P356
10.1593/NEO.07475
P577
2007-10-01T00:00:00Z