TRAIL sensitizes for ionizing irradiation-induced apoptosis through an entirely Bax-dependent mitochondrial cell death pathway.
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The mitochondrial protein Bak is pivotal for gliotoxin-induced apoptosis and a critical host factor of Aspergillus fumigatus virulence in miceIs translational research compatible with preclinical publication strategies?Apoptolidin: induction of apoptosis by a natural product.Bak functionally complements for loss of Bax during p14ARF-induced mitochondrial apoptosis in human cancer cells.Efficacy of a triple treatment with irradiation, agonistic TRAIL receptor antibodies and EGFR blockade.Endogenous Bak inhibitors Mcl-1 and Bcl-xL: differential impact on TRAIL resistance in Bax-deficient carcinoma.Pseudomonas exotoxin A-mediated apoptosis is Bak dependent and preceded by the degradation of Mcl-1Involvement of FOXO transcription factors, TRAIL-FasL/Fas, and sirtuin proteins family in canine coronavirus type II-induced apoptosis.p14(ARF)-induced apoptosis in p53 protein-deficient cells is mediated by BH3-only protein-independent derepression of Bak protein through down-regulation of Mcl-1 and Bcl-xL proteins.Artesunate induces apoptosis via a Bak-mediated caspase-independent intrinsic pathway in human lung adenocarcinoma cells.Taxifolin enhances andrographolide-induced mitotic arrest and apoptosis in human prostate cancer cells via spindle assembly checkpoint activation.In vitro study on apoptosis induced by strontium-89 in human breast carcinoma cell linePrazosin displays anticancer activity against human prostate cancers: targeting DNA and cell cycleCandidate protein biodosimeters of human exposure to ionizing radiation.Low-dose valproic acid enhances radiosensitivity of prostate cancer through acetylated p53-dependent modulation of mitochondrial membrane potential and apoptosis.Death receptor-induced activation of the Chk2- and histone H2AX-associated DNA damage response pathways.Fractionated radiation exposure amplifies the radioresistant nature of prostate cancer cells.Combined modality therapy with TRAIL or agonistic death receptor antibodies.Imatinib enhances human melanoma cell susceptibility to TRAIL-induced cell death: Relationship to Bcl-2 family and caspase activation.Triggering of Toll-like receptor 4 on metastatic breast cancer cells promotes αvβ3-mediated adhesion and invasive migration.Co-treatment with ginsenoside Rh2 and betulinic acid synergistically induces apoptosis in human cancer cells in association with enhanced capsase-8 activation, bax translocation, and cytochrome c release.Gibberellin derivative GA-13315 sensitizes multidrug-resistant cancer cells by antagonizing ABCB1 while agonizes ABCC1.Upregulation of DR5 by proteasome inhibitors potently sensitizes glioma cells to TRAIL-induced apoptosis.Downregulation of Bid is associated with PKCepsilon-mediated TRAIL resistance.Resistance of melanoma cells to TRAIL does not result from upregulation of antiapoptotic proteins by NF-kappaB but is related to downregulation of initiator caspases and DR4.Acute apoptosis by cisplatin requires induction of reactive oxygen species but is not associated with damage to nuclear DNA
P2860
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P2860
TRAIL sensitizes for ionizing irradiation-induced apoptosis through an entirely Bax-dependent mitochondrial cell death pathway.
description
2005 nî lūn-bûn
@nan
2005 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
TRAIL sensitizes for ionizing ...... ochondrial cell death pathway.
@ast
TRAIL sensitizes for ionizing ...... ochondrial cell death pathway.
@en
type
label
TRAIL sensitizes for ionizing ...... ochondrial cell death pathway.
@ast
TRAIL sensitizes for ionizing ...... ochondrial cell death pathway.
@en
prefLabel
TRAIL sensitizes for ionizing ...... ochondrial cell death pathway.
@ast
TRAIL sensitizes for ionizing ...... ochondrial cell death pathway.
@en
P2093
P2860
P356
P1433
P1476
TRAIL sensitizes for ionizing ...... ochondrial cell death pathway.
@en
P2093
Bernd Dörken
Claus Belka
Jana Wendt
Peter T Daniel
Philipp Hemmati
P2860
P2888
P304
P356
10.1038/SJ.ONC.1208580
P407
P577
2005-06-01T00:00:00Z
P5875
P6179
1048831468