Two LIM domain proteins and UNC-96 link UNC-97/pinch to myosin thick filaments in Caenorhabditis elegans muscle.
about
The diversification of the LIM superclass at the base of the metazoa increased subcellular complexity and promoted multicellular specializationILK: a pseudokinase in the center stage of cell-matrix adhesion and signalingPINCH: More than just an adaptor protein in cellular response.The kinase domains of obscurin interact with intercellular adhesion proteinsThe SH3 domain of UNC-89 (obscurin) interacts with paramyosin, a coiled-coil protein, in Caenorhabditis elegans muscle.A LIM-9 (FHL)/SCPL-1 (SCP) complex interacts with the C-terminal protein kinase regions of UNC-89 (obscurin) in Caenorhabditis elegans muscle.Suppressor mutations suggest a surface on PAT-4 (Integrin-linked Kinase) that interacts with UNC-112 (Kindlin).Extensive and modular intrinsically disordered segments in C. elegans TTN-1 and implications in filament binding, elasticity and oblique striation.Molecular structure of sarcomere-to-membrane attachment at M-Lines in C. elegans muscleRegulation of C. elegans presynaptic differentiation and neurite branching via a novel signaling pathway initiated by SAM-10.PKN-1, a homologue of mammalian PKN, is involved in the regulation of muscle contraction and force transmission in C. elegans.The Caenorhabditis elegans paxillin orthologue, PXL-1, is required for pharyngeal muscle contraction and for viabilityMesodermal gene expression during the embryonic and larval development of the articulate brachiopod Terebratalia transversa.Twitchin kinase interacts with MAPKAP kinase 2 in Caenorhabditis elegans striated muscle.Bending amplitude - a new quantitative assay of C. elegans locomotion: identification of phenotypes for mutants in genes encoding muscle focal adhesion componentsZ-line formins promote contractile lattice growth and maintenance in striated muscles of C. elegans.UNC-89 (obscurin) binds to MEL-26, a BTB-domain protein, and affects the function of MEI-1 (katanin) in striated muscle of Caenorhabditis elegans.A crucial role for Ras suppressor-1 (RSU-1) revealed when PINCH and ILK binding is disrupted.A molecular mechanism for the requirement of PAT-4 (integrin-linked kinase (ILK)) for the localization of UNC-112 (Kindlin) to integrin adhesion sites.α-actinin is required for the proper assembly of Z-disk/focal-adhesion-like structures and for efficient locomotion in Caenorhabditis elegans.Dual function of the UNC-45b chaperone with myosin and GATA4 in cardiac developmentUNC-98 and UNC-96 interact with paramyosin to promote its incorporation into thick filaments of Caenorhabditis elegansCPNA-1, a copine domain protein, is located at integrin adhesion sites and is required for myofilament stability in Caenorhabditis elegansA novel protein phosphatase is a binding partner for the protein kinase domains of UNC-89 (Obscurin) in Caenorhabditis elegansZYX-1, the unique zyxin protein of Caenorhabditis elegans, is involved in dystrophin-dependent muscle degenerationThe DH-PH region of the giant protein UNC-89 activates RHO-1 GTPase in Caenorhabditis elegans body wall muscleCSN-5, a component of the COP9 signalosome complex, regulates the levels of UNC-96 and UNC-98, two components of M-lines in Caenorhabditis elegans muscle.Obscurin depletion impairs organization of skeletal muscle in developing zebrafish embryos.High-resolution imaging of muscle attachment structures in Caenorhabditis elegans.Immunofluorescent localization of proteins in Caenorhabditis elegans muscle.Caenorhabditis elegans SORB-1 localizes to integrin adhesion sites and is required for organization of sarcomeres and mitochondria in myocytes.The Role of the UNC-82 Protein Kinase in Organizing Myosin Filaments in Striated Muscle of Caenorhabditis elegans.Ultra-structural time-course study in the C. elegans model for Duchenne muscular dystrophy highlights a crucial role for sarcomere-anchoring structures and sarcolemma integrity in the earliest steps of the muscle degeneration process.
P2860
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P2860
Two LIM domain proteins and UNC-96 link UNC-97/pinch to myosin thick filaments in Caenorhabditis elegans muscle.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Two LIM domain proteins and UN ...... Caenorhabditis elegans muscle.
@ast
Two LIM domain proteins and UN ...... Caenorhabditis elegans muscle.
@en
type
label
Two LIM domain proteins and UN ...... Caenorhabditis elegans muscle.
@ast
Two LIM domain proteins and UN ...... Caenorhabditis elegans muscle.
@en
prefLabel
Two LIM domain proteins and UN ...... Caenorhabditis elegans muscle.
@ast
Two LIM domain proteins and UN ...... Caenorhabditis elegans muscle.
@en
P2093
P2860
P356
P1476
Two LIM domain proteins and UN ...... Caenorhabditis elegans muscle.
@en
P2093
Guy M Benian
Hiroshi Qadota
Kozo Kaibuchi
Kristina B Mercer
Rachel K Miller
P2860
P304
P356
10.1091/MBC.E07-03-0278
P577
2007-08-29T00:00:00Z