Aberrant ORM (yeast)-like protein isoform 3 (ORMDL3) expression dysregulates ceramide homeostasis in cells and ceramide exacerbates allergic asthma in mice
about
Sphingosine-1-Phosphate Signaling in Immune Cells and Inflammation: Roles and Therapeutic Potential1-Deoxysphingolipids Encountered Exogenously and Made de Novo: Dangerous Mysteries inside an EnigmaPulmonary ORMDL3 is critical for induction of Alternaria-induced allergic airways disease.Protein disulfide isomerase-endoplasmic reticulum resident protein 57 regulates allergen-induced airways inflammation, fibrosis, and hyperresponsiveness.ORMDL3 contributes to the risk of atherosclerosis in Chinese Han population and mediates oxidized low-density lipoprotein-induced autophagy in endothelial cells.Airway reactivity and sphingolipids-implications for childhood asthmaA Phosphorylatable Sphingosine Analog Induces Airway Smooth Muscle Cytostasis and Reverses Airway Hyperresponsiveness in Experimental Asthma.Epithelial ER Stress in Crohn's Disease and Ulcerative Colitis.The role of ORMDL proteins, guardians of cellular sphingolipids, in asthma.Intratracheal myriocin enhances allergen-induced Th2 inflammation and airway hyper-responsiveness.Sphingosine 1-Phosphate: A Novel Target for Lung Disorders.Negative regulatory roles of ORMDL3 in the FcεRI-triggered expression of proinflammatory mediators and chemotactic response in murine mast cells.ORMDL proteins regulate ceramide levels during sterile inflammation.Neutrophil elastase increases airway ceramide levels via upregulation of serine palmitoyltransferase.Oroscomucoid like protein 3 (ORMDL3) transgenic mice have reduced levels of sphingolipids including sphingosine-1-phosphate and ceramide.The Role of Sphingosine-1-Phosphate and Ceramide-1-Phosphate in Inflammation and Cancer.Distinct Serum Sphingolipid Profiles among School-aged Children with Exercise-induced Wheeze and Asthma Persistence.Lessons from ten years of genome-wide association studies of asthma.A decade of research on the 17q12-21 asthma locus: Piecing together the puzzle.
P2860
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P2860
Aberrant ORM (yeast)-like protein isoform 3 (ORMDL3) expression dysregulates ceramide homeostasis in cells and ceramide exacerbates allergic asthma in mice
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年学术文章
@wuu
2015年学术文章
@zh-cn
2015年学术文章
@zh-hans
2015年学术文章
@zh-my
2015年学术文章
@zh-sg
2015年學術文章
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name
Aberrant ORM (yeast)-like prot ...... rbates allergic asthma in mice
@ast
Aberrant ORM (yeast)-like prot ...... rbates allergic asthma in mice
@en
type
label
Aberrant ORM (yeast)-like prot ...... rbates allergic asthma in mice
@ast
Aberrant ORM (yeast)-like prot ...... rbates allergic asthma in mice
@en
prefLabel
Aberrant ORM (yeast)-like prot ...... rbates allergic asthma in mice
@ast
Aberrant ORM (yeast)-like prot ...... rbates allergic asthma in mice
@en
P2093
P2860
P1476
Aberrant ORM (yeast)-like prot ...... rbates allergic asthma in mice
@en
P2093
Alison Montpetit
Clement Oyeniran
Daniel H Conrad
Dorit Avni
Jason Newton
Jeremy C Allegood
Michael Maceyka
Nitai C Hait
Sheldon Milstien
Wei-Ching Huang
P2860
P304
1035-46.e6
P356
10.1016/J.JACI.2015.02.031
P407
P577
2015-04-01T00:00:00Z